Carbon nanotube-enhanced electrochemical aptasensor for the detection of thrombin

Liu, Xiaorong; Li, Yan; Zheng, Jianbin; Zhang, Juncai; Sheng, Qinglin

doi:10.1016/j.talanta.2010.03.013

Cited by 54 publications

(22 citation statements)

References 49 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…(44) Nowadays, there are a countless number of devices available to perform that function. In this way, we can find electrochemical biosensors, based on CNTs (58) or gold electrodes (59) for the sensitive and robust determination of human α-thrombin with anti-thrombin aptamer, lysozime, (60) several small molecules, (61) or even whole cells in human blood. (62) Another versatile alternative is the light-based biosensors that include chemiluminescence, (63) fluorescence, (64) and colorimetric sensors.…”

Section: Aptamersmentioning

confidence: 99%

Selective Nanoparticles in Microextraction

Ríos-Gómez

Lasarte‐Aragonés

Cárdenas

et al. 2016

Encyclopedia of Analytical Chemistry

View full text Add to dashboard Cite

Sorption capacity is a critical issue in microextraction techniques where the amount of sorbent is reduced to the low milligram range and even lower. In this context, the use of sorbents with a high superficial area is really desirable. Nanoparticles (NPs) fulfill this main requirement while, at the same time, provide the analyst with a wide variety of interaction chemistries that can be easily selected depending on the analytical problem under study. In addition, certain NPs present especial properties (e.g. superparamagnetism) that make them so attractive in the microextraction context. Focusing on sorption capacity is meaningless when complex samples, the usual situation in Bioanalysis, are processed as matrix components may overload the sorbent avoiding the extraction of the target analytes. In this scenario, selectivity then becomes a critical variable of concern. This article discusses the role of selectivity in microextraction and provides a general overview of the main coatings used to boost the selectivity of NPs. In particular, this article describes the use of two groups of coatings as selectivity enhancers. On the one hand, the use of synthetic polymers including molecularly imprinted polymers (MIPs) and restricted access materials (RAMs) is a well‐established alternative in analytical sciences. On the other hand, biopolymers, such as antibodies and aptamers, exploit biorecognition that is by far the most selective interaction. Both alternatives are described in detail in this article.

show abstract

Section: Aptamersmentioning

confidence: 99%

Selective Nanoparticles in Microextraction

Ríos-Gómez

Lasarte‐Aragonés

Cárdenas

et al. 2016

Encyclopedia of Analytical Chemistry

View full text Add to dashboard Cite

show abstract

“…Many different procedures have been used to improve the sensitivity of the G-quadruplex electrochemical aptasensors using amplification strategies based on redox labels, such as ferrocene [72][73][74][75][76][77][78][79][80] A c c e p t e d M a n u s c r i p t 13 transducers have been employed, such as modified platinum [89] or carbon electrodes [64,76,[89][90][91][92].…”

Section: Structure-switching G-quadruplex Electrochemical Aptasensorsmentioning

confidence: 99%

Redox behaviour of G-quadruplexes

Chiorcea-Paquim

Oliveira-Brett

2014

Electrochimica Acta

View full text Add to dashboard Cite

Please cite this article as: A.-M. Chiorcea-Paquim, A.M. OliveiraBrett, Redox behaviour of G-quadruplexes, Electrochimica Acta (2013), http://dx.doi.org/10.1016/j.electacta. 2013.07.150 This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain. Page 1 of 45A c c e p t e d M a n u s c r i p t Redox behaviour of G-quadruplexes

show abstract

“…Moreover, as in the case of metal nanoparticles, CNTs have been used to increase the surface area of working electrodes and to incorporate specific redox probes [98][99][100]. A selective potentiometric sensor using CNTs was developed in the work discussed in Ref.…”

Section: Graphene and Carbon Nanotubesmentioning

confidence: 99%

Electrochemical nanomaterial-based nucleic acid aptasensors

Palchetti

Mascini

2012

Anal Bioanal Chem

View full text Add to dashboard Cite

Recent progress in the development of electrochemical nanomaterial-aptamer-based biosensors is summarized. Aptamers are nucleic acid ligands that can be generated against amino acids, drugs, proteins, and other molecules. They are isolated from a large random library of synthetic nucleic acids by an iterative process of binding, separation, and amplification, called systematic evolution of ligands by exponential enrichment (SELEX). In this review, different methods of integrating aptamers with different nanomaterials and nanoparticles for electrochemical biosensing application are described.

show abstract

Carbon nanotube-enhanced electrochemical aptasensor for the detection of thrombin

Cited by 54 publications

References 49 publications

Selective Nanoparticles in Microextraction

Selective Nanoparticles in Microextraction

Redox behaviour of G-quadruplexes

Electrochemical nanomaterial-based nucleic acid aptasensors

Contact Info

Product

Resources

About