Carbon nanotube-based coatings on titanium

Długoń, E.; Simka, Wojciech; Frączek-Szczypta, Aneta; Niemiec, Wiktor; Markowski, Jarosław; Szymańska, Marzena; Błażewicz, M.

doi:10.1007/s12034-015-1019-4

Cited by 22 publications

(9 citation statements)

References 26 publications

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“…Several results confirm the hypothesis that the carbon component may act as chondrogenic material [51,52]. Carbon materials, including carbon fibres and carbon nanotubes, have been successfully used in the treatment of cartilage defects.…”

Section: Resultssupporting

confidence: 70%

PLA-Based Hybrid and Composite Electrospun Fibrous Scaffolds as Potential Materials for Tissue Engineering

Magiera

Markowski

Menaszek

et al. 2017

Journal of Nanomaterials

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The aim of the study was to manufacture poly(lactic acid)-(PLA-) based nanofibrous nonwovens that were modified using two types of modifiers, namely, gelatin-(GEL-) based nanofibres and carbon nanotubes (CNT). Hybrid nonwovens consisting of PLA and GEL nanofibres (PLA/GEL), as well as CNT-modified PLA nanofibres with GEL nanofibres (PLA + CNT/GEL), in the form of mats, were manufactured using concurrent-electrospinning technique (co-ES). The ability of such hybrid structures as potential scaffolds for tissue engineering was studied. Both types of hybrid samples and one-component PLA and CNTs-modified PLA mats were investigated using scanning electron microscopy (SEM), water contact angle measurements, and biological and mechanical tests. The morphology, microstructure, and selected properties of the materials were analyzed. Biocompatibility and bioactivity in contact with normal human osteoblasts (NHOst) were studied. The coelectrospun PLA and GEL nanofibres retained their structures in hybrid samples. Both types of hybrid nonwovens were not cytotoxic and showed better osteoinductivity in comparison to scaffolds made from pure PLA. These samples also showed significantly reduced hydrophobicity compared to one-component PLA nonwovens. The CNT-contained PLA nanofibres improved mechanical properties of hybrid samples and such a 3D system appears to be interesting for potential application as a tissue engineering scaffold.

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Section: Resultssupporting

confidence: 70%

PLA-Based Hybrid and Composite Electrospun Fibrous Scaffolds as Potential Materials for Tissue Engineering

Magiera

Markowski

Menaszek

et al. 2017

Journal of Nanomaterials

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“…Thanks to this, they are increasingly applied in medicine and diagnostics, including tissue engineering [1,2]. These two-dimensional carbon structures are used, among others, to functionalize materials designed for implants, where CNTs can support osseointegration [3,4].…”

Section: Introductionmentioning

confidence: 99%

“…The biocompatibility of CNTs in orthopedic applications was established by in vitro studies, which showed accelerated bone growth and increased proliferation and differentiation of osteoblasts [5][6][7][8][9][10]. The most popular kind of metal substrate for CNTs is titanium [3,[11][12][13][14][15][16][17][18], which combines some beneficial mechanical properties and biocompatibility with a chemical in vivo susceptibility [11]. Several studies evaluated the body's reaction in the presence of carbon nanotubes, demonstrating a high vitality of osteoblasts compared to the pure titanium substrate [14][15][16]19].…”

Section: Introductionmentioning

confidence: 99%

Comparison of Properties of the Hybrid and Bilayer MWCNTs—Hydroxyapatite Coatings on Ti Alloy

et al. 2019

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Carbon nanotubes are proposed for reinforcement of the hydroxyapatite coatings to improve their adhesion, resistance to mechanical loads, biocompatibility, bioactivity, corrosion resistance, and antibacterial protection. So far, research has shown that all these properties are highly susceptible to the composition and microstructure of coatings. The present research is aimed at studies of multi-wall carbon nanotubes in three different combinations: multi-wall carbon nanotubes layer, bilayer coating composed of multi-wall carbon nanotubes deposited on nanohydroxyapatite deposit, and hybrid coating comprised of simultaneously deposited nanohydroxyapatite, multi-wall carbon nanotubes, nanosilver, and nanocopper. The electrophoretic deposition method was applied for the fabrication of the coatings. Atomic force microscopy, scanning electron microscopy and X-ray electron diffraction spectroscopy, and measurements of water contact angle were applied to study the chemical and phase composition, roughness, adhesion strength and wettability of the coatings. The results show that the pure multi-wall carbon nanotubes layer possesses the best adhesion strength, mechanical properties, and biocompatibility. Such behavior may be attributed to the applied deposition method, resulting in the high hardness of the coating and high adhesion of carbon nanotubes to the substrate. On the other hand, bilayer coating, and hybrid coating demonstrated insufficient properties, which could be the reason for the presence of soft porous hydroxyapatite and some agglomerates of nanometals in prepared coatings.

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“…Carbon micro-and nanofibrous materials obtained by heat treatment of the polymer precursor (carbonization) at low temperatures (about 1000°C) integrate well with tissues and can undergo a slow oxidation in the biological environment, turning into organic forms that do not pose a threat to the body [23,24]. Our research shows that both the micro and carbon nanofibers have a potential in the treatment and regeneration of the cartilage [25,26].…”

Section: Introductionmentioning

confidence: 74%

“…One of the objectives of the surface modification of carbon nanofibers is to develop an active material that could be used to regenerate osteochondral tissue, e.g., for laryngology. The previous literature reports indicate that carbon materials, including carbon fibers and carbon nanotubes, may act as substrates with chondrogenic properties [25,26]. Thus, the modified carbon nanofibers with a Si/Ca sol may be suitable substrates for osteochondral tissue.…”

Section: Resultsmentioning

confidence: 99%

Carbon Nanofibers Coated with Silicon/Calcium-Based Compounds for Medical Application

Smółka

Długoń

Jeleń

et al. 2019

Journal of Nanomaterials

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The aim of this work was to develop a method for the manufacture of carbon nanofibers in the form of mats containing silicon and calcium compounds with potential biomedical application. Carbon nanofibers (ECNF) were prepared from the electrospun polyacrylonitrile (PAN) nanofibers. The electrospun polymer nanofibers were heat treated up to 1000°C to obtain carbon nanofibers. The surface of ECNF was covered with a silica-calcium sol (ECNF+Si/Ca) by dip-coating technique followed by the stabilization process. Both types of carbon nanofibers, i.e., the as-received and covered with the sol, were tested to confirm their osteoconductive properties. Biological tests were performed, including genotoxicity, cytotoxicity, and alkaline phosphatase (ALP) activity. Morphology of adhering cells to nanofiber surface was described. The nanofibers were subjected to a bioactivity test in contact with SBF artificial plasma. Biological tests have revealed that the nanofiber-modified ECNF+Si/Ca in contact with osteoblast cells were biocompatible, and the level of cytotoxicity was lower compared to the control. The ALP activity of the modified nanofibers was higher than nonmodified nanofibers and indicates potential applications of such carbon materials in the form of mats as a substrate for bone tissue regeneration.

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Carbon nanotube-based coatings on titanium

Cited by 22 publications

References 26 publications

PLA-Based Hybrid and Composite Electrospun Fibrous Scaffolds as Potential Materials for Tissue Engineering

PLA-Based Hybrid and Composite Electrospun Fibrous Scaffolds as Potential Materials for Tissue Engineering

Comparison of Properties of the Hybrid and Bilayer MWCNTs—Hydroxyapatite Coatings on Ti Alloy

Carbon Nanofibers Coated with Silicon/Calcium-Based Compounds for Medical Application

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