Carbon Black-Carbon Nanotube Co-Doped Polyimide Sensors for Simultaneous Determination of Ascorbic Acid, Uric Acid, and Dopamine

Wang, Yue; Tian, Yang; Hasebe, Yasushi; Zhang, Zhiqiang; Tao, D.

doi:10.3390/ma11091691

Cited by 21 publications

(13 citation statements)

References 40 publications

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“…The application of carbon-based nanomaterials to develop biosensors received huge attention because of their advantages, such as a large surface-to-volume ratio and good chemical stability and biocompatibility [51,52]. For instance, carbon nanotubes (CNTs), carbon nanodots (CNDs), and graphene are the most widely known and used carbon-based nanomaterials [53][54][55], which are suitable for biological application due to their biocompatibility and high conductivity. In particular, CNDs are considered to be candidates for developing fluorescence and electrochemical biosensors due to their unique optical and electrochemical properties [56,57].…”

Section: Carbon-based Nanomaterials In Biosensorsmentioning

confidence: 99%

Highly Sensitive Biosensors Based on Biomolecules and Functional Nanomaterials Depending on the Types of Nanomaterials: A Perspective Review

et al. 2020

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Biosensors are very important for detecting target molecules with high accuracy, selectivity, and signal-to-noise ratio. Biosensors developed using biomolecules such as enzymes or nucleic acids which were used as the probes for detecting the target molecules were studied widely due to their advantages. For example, enzymes can react with certain molecules rapidly and selectively, and nucleic acids can bind to their complementary sequences delicately in nanoscale. In addition, biomolecules can be immobilized and conjugated with other materials by surface modification through the recombination or introduction of chemical linkers. However, these biosensors have some essential limitations because of instability and low signal strength derived from the detector biomolecules. Functional nanomaterials offer a solution to overcome these limitations of biomolecules by hybridization with or replacing the biomolecules. Functional nanomaterials can give advantages for developing biosensors including the increment of electrochemical signals, retention of activity of biomolecules for a long-term period, and extension of investigating tools by using its unique plasmonic and optical properties. Up to now, various nanomaterials were synthesized and reported, from widely used gold nanoparticles to novel nanomaterials that are either carbon-based or transition-metal dichalcogenide (TMD)-based. These nanomaterials were utilized either by themselves or by hybridization with other nanomaterials to develop highly sensitive biosensors. In this review, highly sensitive biosensors developed from excellent novel nanomaterials are discussed through a selective overview of recently reported researches. We also suggest creative breakthroughs for the development of next-generation biosensors using the novel nanomaterials for detecting harmful target molecules with high sensitivity.

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Section: Carbon-based Nanomaterials In Biosensorsmentioning

confidence: 99%

Highly Sensitive Biosensors Based on Biomolecules and Functional Nanomaterials Depending on the Types of Nanomaterials: A Perspective Review

et al. 2020

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“…This fabricated sensor showed the enhanced sensitivity to only two of the analyte's DA and UA, with lowest detection limit of 1.9 µM and 3 µM respectively. Applicability of the sensor was tested in human urine samples with good recovery values [81]. Another sensor with a simplified interface comprising carbon black-chitosan mixture was tuned as a water soluble homogenous ink deposited on a GCE for concurrent detection of AA, UA and DA as shown in Figure 3A with a lower detection limit of 0.1 µM achieved for all the three analytes.…”

Section: Electrochemical Detection Strategies For Multi-analyte Detecmentioning

confidence: 99%

Metabolic Syndrome—An Emerging Constellation of Risk Factors: Electrochemical Detection Strategies

Madhurantakam

Devi

Babu

et al. 2019

Sensors

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Metabolic syndrome is a condition that results from dysfunction of different metabolic pathways leading to increased risk of disorders such as hyperglycemia, atherosclerosis, cardiovascular diseases, cancer, neurodegenerative disorders etc. As this condition cannot be diagnosed based on a single marker, multiple markers need to be detected and quantified to assess the risk facing an individual of metabolic syndrome. In this context, chemical- and bio-sensors capable of detecting multiple analytes may provide an appropriate diagnostic strategy. Research in this field has resulted in the evolution of sensors from the first generation to a fourth generation of ‘smart’ sensors. A shift in the sensing paradigm involving the sensing element and transduction strategy has also resulted in remarkable advancements in biomedical diagnostics particularly in terms of higher sensitivity and selectivity towards analyte molecule and rapid response time. This review encapsulates the significant advancements reported so far in the field of sensors developed for biomarkers of metabolic syndrome.

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“…These sensors have relative operational simplicity, miniaturization and automation potential, low cost and high sensitivity [12,13]. Among the various materials available for the manufacture of new sensors, carbon black (CB) has stood out [14][15][16][17]. This material is made up of over 90 % carbon, its production occurs through thermal decomposition or partial burning of organic compounds from petroleum, the first being carried out under very controlled and optimized conditions in order to obtain a material with well-defined properties such as conductivity, specific surface and particle size [18].…”

Section: Introductionmentioning

confidence: 99%

A New Electrochemical Sensor Based on Carbon Black Modified With Palladium Nanoparticles for Direct Determination of 17α‐Ethinylestradiol in Real Samples

Fernandes

Bernardino

et al. 2022

Electroanalysis

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Electrochemical sensors to quantify concentrations of emerging pollutants have attracted great attention from the industry and scientific community. Nanomaterials such as carbon black have been applied in sensors to identify substances that are toxic to the environment and human health due to their excellent electroanalytical properties. The aim of the study was to develop a novel electrochemical sensor for the endocrine disruptor hormone determination. To our knowledge, for the first time the synthesis of material based on carbon black containing immobilized palladium nanoparticles, with the application for the hormone ethinylestradiol, is reported in the literature. The material was synthesized, characterized, and applied to the determination in tap water and human urine of the synthetic hormone 17α-ethinylestradiol (EE2), which is currently considered an emerging pollutant. The morphology, structure and electrochemical performance of the sensors were characterized by scanning electron microscopy (SEM) and cyclic voltammetry (CV). Differential pulse voltammetry (DPV) in sodium phosphate buffer solution at pH 5.0 allowed the generation of a method to quantify the concentration of 17αethinylestradiol in a linear range of 0.5-119.0 μmol L À 1 , obtaining 81.0 nmol L À 1 of calculated limit of detection (LOD). The system was efficient in detecting 17αethinylestradiol in real urine samples and showed no interferences for ascorbic acid, uric acid, progesterone, and dopamine. It is noteworthy that the results obtained showed good recovery values, considering that the urine samples were not previously treated or pre-concentrated, which suggests the development of an electrochemical sensor that works in situ and in real time to monitor relevant substances in the control clinical and environmental, with the possibility of point-of-care analyses.

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Carbon Black-Carbon Nanotube Co-Doped Polyimide Sensors for Simultaneous Determination of Ascorbic Acid, Uric Acid, and Dopamine

Cited by 21 publications

References 40 publications

Highly Sensitive Biosensors Based on Biomolecules and Functional Nanomaterials Depending on the Types of Nanomaterials: A Perspective Review

Highly Sensitive Biosensors Based on Biomolecules and Functional Nanomaterials Depending on the Types of Nanomaterials: A Perspective Review

Metabolic Syndrome—An Emerging Constellation of Risk Factors: Electrochemical Detection Strategies

A New Electrochemical Sensor Based on Carbon Black Modified With Palladium Nanoparticles for Direct Determination of 17α‐Ethinylestradiol in Real Samples

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