Carbon-Based Nanomaterials for Biomedical Applications: A Recent Study

Maiti, Debabrata; Tong, Xiangmin; Mou, Xiaozhou; Yang, Kai

doi:10.3389/fphar.2018.01401

Cited by 502 publications

(219 citation statements)

References 177 publications

(194 reference statements)

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“…Carbon nanotubes have unique electrical properties, ranging from metallic, semiconducting to superconducting conductivity and even different parts of the same CNT exhibit different electronic conductivity [83,84,85]. Their controllable electronic conductivity depends largely on their alignment, diameter, aspect ratio, and chirality.…”

Section: Advantages For Using Cnt Composite Materials For Bone Tismentioning

confidence: 99%

Applications of Carbon Nanotubes in Bone Tissue Regeneration and Engineering: Superiority, Concerns, Current Advancements, and Prospects

et al. 2019

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With advances in bone tissue regeneration and engineering technology, various biomaterials as artificial bone substitutes have been widely developed and innovated for the treatment of bone defects or diseases. However, there are no available natural and synthetic biomaterials replicating the natural bone structure and properties under physiological conditions. The characteristic properties of carbon nanotubes (CNTs) make them an ideal candidate for developing innovative biomimetic materials in the bone biomedical field. Indeed, CNT-based materials and their composites possess the promising potential to revolutionize the design and integration of bone scaffolds or implants, as well as drug therapeutic systems. This review summarizes the unique physicochemical and biomedical properties of CNTs as structural biomaterials and reinforcing agents for bone repair as well as provides coverage of recent concerns and advancements in CNT-based materials and composites for bone tissue regeneration and engineering. Moreover, this review discusses the research progress in the design and development of novel CNT-based delivery systems in the field of bone tissue engineering.

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Section: Advantages For Using Cnt Composite Materials For Bone Tismentioning

confidence: 99%

Applications of Carbon Nanotubes in Bone Tissue Regeneration and Engineering: Superiority, Concerns, Current Advancements, and Prospects

et al. 2019

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“…Moreover, GO is utilized in osteogenic stem cells to study [ 59 , 60 , 61 ] chondrogenesis, adipogenesis, epithelial genesis, myogenesis, cardiomyogenesis, and neurogenesis [ 62 , 63 , 64 , 65 , 66 , 67 ]. Investigations in the area of CBNs for biomedical applications—like tissue engineering [ 53 ], biosensors, drug delivery, cancer therapy [ 68 ], and orthopedic BCs [ 2 ]—have attracted widespread attention because of their incomparable physical, mechanical, and electrical properties, such as unique shape, large surface specific area, size, thermal, electrical, structural, and optical diversity [ 68 , 69 , 70 ], which are widely investigated and make them (CBNs) appropriate as reinforcement agents as shown in Figure 5 [ 53 , 69 ]. Many investigations have focused on removing the defects of BCs due to the high utilization of them [ 71 , 72 , 73 ].…”

Section: Use Of Carbon Compounds In Pmma-based Bcsmentioning

confidence: 99%

Polymethyl Methacrylate-Based Bone Cements Containing Carbon Nanotubes and Graphene Oxide: An Overview of Physical, Mechanical, and Biological Properties

et al. 2020

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Every year, millions of people in the world get bone diseases and need orthopedic surgery as one of the most important treatments. Owing to their superior properties, such as acceptable biocompatibility and providing great primary bone fixation with the implant, polymethyl methacrylate (PMMA)-based bone cements (BCs) are among the essential materials as fixation implants in different orthopedic and trauma surgeries. On the other hand, these BCs have some disadvantages, including Lack of bone formation and bioactivity, and low mechanical properties, which can lead to bone cement (BC) failure. Hence, plenty of studies have been concentrating on eliminating BC failures by using different kinds of ceramics and polymers for reinforcement and also by producing composite materials. This review article aims to evaluate mechanical properties, self-setting characteristics, biocompatibility, and bioactivity of the PMMA-based BCs composites containing carbon nanotubes (CNTs), graphene oxide (GO), and carbon-based compounds. In the present study, we compared the effects of CNTs and GO as reinforcement agents in the PMMA-based BCs. Upcoming study on the PMMA-based BCs should concentrate on trialing combinations of these carbon-based reinforcing agents as this might improve beneficial characteristics.

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“…The exceptional properties of these materials have embraced the technological developments in various areas, like high tensile strength materials, catalysis, electronics and communications, biomedical applications, and sensing. The biomedical field extensively utilizes CBNs for drug delivery, therapeutics and biosensing due to their inherently favorable properties [26].…”

Section: Introductionmentioning

confidence: 99%

Carbon-Based Nanomaterials for Plasmonic Sensors: A Review

Gupta

Pathak

Semwal

2019

Sensors

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The surface plasmon resonance (SPR) technique is a remarkable tool, with applications in almost every area of science and technology. Sensing is the foremost and majorly explored application of SPR technique. The last few decades have seen a surge in SPR sensor research related to sensitivity enhancement and innovative target materials for specificity. Nanotechnological advances have augmented the SPR sensor research tremendously by employing nanomaterials in the design of SPR-based sensors, owing to their manifold properties. Carbon-based nanomaterials, like graphene and its derivatives (graphene oxide (GO)), (reduced graphene oxide (rGO)), carbon nanotubes (CNTs), and their nanocomposites, have revolutionized the field of sensing due to their extraordinary properties, such as large surface area, easy synthesis, tunable optical properties, and strong compatible adsorption of biomolecules. In SPR based sensors carbon-based nanomaterials have been used to act as a plasmonic layer, as the sensitivity enhancement material, and to provide the large surface area and compatibility for immobilizing various biomolecules, such as enzymes, DNA, antibodies, and antigens, in the design of the sensing layer. In this review, we report the role of carbon-based nanomaterials in SPR-based sensors, their current developments, and challenges.

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Carbon-Based Nanomaterials for Biomedical Applications: A Recent Study

Cited by 502 publications

References 177 publications

Applications of Carbon Nanotubes in Bone Tissue Regeneration and Engineering: Superiority, Concerns, Current Advancements, and Prospects

Applications of Carbon Nanotubes in Bone Tissue Regeneration and Engineering: Superiority, Concerns, Current Advancements, and Prospects

Polymethyl Methacrylate-Based Bone Cements Containing Carbon Nanotubes and Graphene Oxide: An Overview of Physical, Mechanical, and Biological Properties

Carbon-Based Nanomaterials for Plasmonic Sensors: A Review

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