Carbohydrate Metabolism and the Skin

Urbach, Erich

doi:10.1001/archderm.1945.01510290006001

Cited by 39 publications

(9 citation statements)

References 27 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Urbach [4] showed that skin sugar levels run parallel to the blood sugar levels. Cutaneous signs of diabetes mellitus are extremely valuable to the clinician as some of them can alert the physician to the diagnosis of diabetes and also reflect the status of glycemic control and lipid metabolism [5]. It has been observed that without control of diabetes, the treatment response is poor in cutaneous complications [6].…”

Section: Introductionmentioning

confidence: 99%

Prevalence of Cutaneous Manifestations of Diabetes Mellitus

Verma¹

2013

IOSR-JDMS

View full text Add to dashboard Cite

show abstract

Section: Introductionmentioning

confidence: 99%

Prevalence of Cutaneous Manifestations of Diabetes Mellitus

Verma¹

2013

IOSR-JDMS

View full text Add to dashboard Cite

show abstract

“…3 Cutaneous signs of diabetes mellitus are extremely valuable to the clinician as some of them can alert the physician to the diagnosis of diabetes and also reflect the status of glycemic control and lipid metabolism. 4 It has been observed that without control of diabetes, the treatment response is poor in cutaneous complications. 5 Thus, the present study was done to analyse the pattern of diabetic dermatitis in view of increasing prevalence of diabetes in the present scenario of sedentary life style in the general population.…”

Section: Introductionmentioning

confidence: 99%

Study on cutaneous manifestation among type II diabetes mellitus in rural Pondicherry, India

Kandaswamy

Kanagarajan

Suganthi

et al. 2016

Int J Community Med Public Health

View full text Add to dashboard Cite

INTRODUCTIONDiabetes has emerged as a major public health problem in India. According to diabetes atlas published by the international diabetes federation (IDF), there was an estimated 40.9 million people with diabetes in India and this number is predicted to rise to almost 69.9 million people by 2025.1 The organs affected by diabetes include the cardiovascular, renal and nervous systems, eyes and the skin.2 The skin is affected by both the acute metabolic derangements and the chronic degenerative complications of diabetes. Although the mechanism for many diabetes associated skin conditions remains unknown, the pathogenesis of others is linked to abnormal carbohydrate ABSTRACT Background: Diabetes has emerged as a major public health care problem in India. According to Diabetes atlas published by the International Diabetes Federation (IDF), there was on 2007 an estimated 40.9 million people with diabetes in India and this number is predicted to rise to almost 69.9 million people by 2025. The skin is affected by both the acute metabolic derangements and the chronic degenerative complications of diabetes. Cutaneous signs of diabetes mellitus are extremely valuable to the clinician as some of them can alert the physician to the diagnosis of diabetes and also reflect the status of glycemic control and lipid metabolism. The objective was to study the cutaneous manifestations in patient with type II diabetes mellitus. Method: The present cross sectional study was conducted at field based area of Mahatma Gandhi Medical College and Research Institute, Puducherry, India from January 2013 to June 2013. Data collection was done using pretested proforma and information regarding age, sex, duration of diabetes, treatment, blood glucose (Fasting, Post prandial), urine examination, specific investigations and skin lesions were taken. A complete physical and dermatological examinations of the patients was done. Statistical analysis was done. Results: Among the total number of 166 patients studied, there were 44 (26.50%) women and 122 (73.49%) men; the male: female ratio was 3:1, of the total diabetic patients, majority 85 (51.2%) had <5 years of duration of diabetes. Among the cutaneous disorders found in patients with diabetes, majority of the patients had cruralcandidal intertrigo and patients each had acquired ichthyosis and tineacruris. Trophic ulcer and xerosis were found in 8% patients followed by furunclosis and psoriasis vulgaris seven percent (7%). Conclusion: The failure to give adequate skin care in patients with diabetes may be attributed to lack of patient's knowledge of the disease.

show abstract

“…Soon after that, in 1945, Urbach and Lentz revealed the fact that a high sugar diet was associated with elevated serum and skin sugar levels and that a hypoglycemic diet lowered the skin's sugar level (14).…”

Section: Introductionmentioning

confidence: 99%

Glycation: Implication in Perceived Age and Dermatology

2014

RoJCED

View full text Add to dashboard Cite

Perceived age comprises different facial features and it is associated with multiple external factors, one of which is high levels of serum glucose. Modern Western diet is associated with systemic elevated sugar levels. Excess sugars react with proteins, forming protein-bounded sugars involved in the process named glycation and resulting in the formation of advanced glycation end products or AGEs. This article reviews the pathophysiological mechanisms involved in glycation and AGEs' impact on tissues and organs of both healthy and diabetic individuals. Dietary advice must be an important part of medical consultation, emphasizing the benefi ts of a hypoglycemic diet. Future research aimed at discovering universal molecules that could interfere with AGE's will be a major breakthrough in the management of diabetes and aging related conditions.

show abstract

Carbohydrate Metabolism and the Skin

Cited by 39 publications

References 27 publications

Prevalence of Cutaneous Manifestations of Diabetes Mellitus

Prevalence of Cutaneous Manifestations of Diabetes Mellitus

Study on cutaneous manifestation among type II diabetes mellitus in rural Pondicherry, India

Glycation: Implication in Perceived Age and Dermatology

Contact Info

Product

Resources

About