Características fisicoquímicas de los gases y partículas contaminantes del aire. Su impacto en el asma

Allergy�Rhinol (Providence)

Sánchez²

2018

BackgroundEpidemiological and experimental studies suggest that air pollution has a negative impact on human health and modifies the environment. However, the clinical implications of changes in environmental allergens secondary to air pollution have been little studied.ObjectivesTo explore if the growth conditions of the Cynodon dactylon (rural vs urban area) modify the inflammatory response among patients with allergic rhinitis.Methodology: Two extracts were prepared for diagnostic test with Cyn d proteins obtained from rural and urban environment. Skin prick test (SPT), nasal challenge test (NCT), and eosinophil count in nasal mucus were performed in 3 groups: healthy subjects without rhinitis, rhinitis with (+) Cyn d, and rhinitis with (−) Cyn d.ResultsThere was a 97% concordance in the positive and negative results of the SPT with the 2 extracts. However, Cyn d-urban extract generated larger wheals (P = .03) and a higher number of patients with rhinitis presented a positive NCT to this extract (n = 7 vs 14, P = .04). Patients with positive NCT had a significant increase in eosinophils in mucus, but there was no difference between the extracts. The healthy controls did not react to the extracts tested in the skin or nasal test.ConclusionThe findings suggest that the growth conditions in urban area of Cynodon dactylon can generate changes in the protein extract and have clinical implications in patients with allergic rhinitis.

Differences in the Nasal Inflammatory Response toCynodon dactylonFrom Rural and Urban Areas in Patients With Allergic Rhinitis

Allergy�Rhinol (Providence)

Sánchez²

2018

Guía de dermatitis atópica. Consenso de la Sociedad Latinoamericana de Alergia, Asma e Inmunología

Páez

Macías

et al. 2014

RAM

As in other regions, the incidence of atopic dermatitis in Latin America has been increasing in recent years. Although there are several clinical guidelines, many of their recommendations cannot be universal since they depend on the characteristics of each region. Thus, we decided to create a consensus guideline on atopic dermatitis applicable in Latin America and other tropical regions, taking into account socio-economic, geographical, cultural and health care system characteristics. The Latin American Society of Allergy Asthma and Immunology (SLAAI) conducted a systematic search for articles related to the pathophysiology, diagnosis and treatment of dermatitis using various electronic resources such as Google, Pubmed, EMBASE (Ovid) and Cochrane data base. We have also looked for all published articles in Latin America on the subject using LILACS (Latin American and Caribbean Literature on Health Sciences) database. Each section was reviewed by at least two members of the committee, and the final version was subsequently approved by all of them, using the Delphi methodology for consensus building. Afterward, the final document was shared for external evaluation with physicians, specialists (allergists, dermatologists and pediatricians), patients and academic institutions such as universities and scientific societies related to the topic. All recommendations made by these groups were taken into account for the final drafting of the document. There are few original studies conducted in Latin America about dermatitis; however, we were able to create a practical guideline for Latin America taking into account the particularities of the region. Moreover, the integral management was highlighted including many of the recommendations from different participants in the health care of this disease (patients, families, primary care physicians and specialists). This practical guide presents a concise approach to the diagnosis and management of atopic dermatitis that can be helpful for medical staff, patients and their families in Latin America.

Puntos clave en el tratamiento de la dermatitis en Latinoamérica. El consenso SLAAI

Páez

Macías-Weinmann

et al. 2015

RAM

La incidencia de la dermatitis atópica en Latinoamérica, al igual que en otras regiones del mundo, se incrementó en los últimos años. El Consenso SLAAI se basa en una búsqueda sistemática de artículos relacionados con la dermatitis, en cuanto a su fisiopatología, tratamiento y repercusión en Latinoamérica; en el consenso se revisó la metodología Delphi (Revista Alergia México 2014;61:178-211). En este artículo resaltamos los puntos clave del consenso y las consideraciones particulares en Latinoamérica.