Caractérisation biomécanique des ligaments utérins. Implication en statique, en pelvienne

Rivaux, G.; Rubod, Chrystèle; Dedet, B.; Brieu, Mathias; Gabriel, Boris; Landscheere, L. De; Devos, Patrick; Delmas, V.; Cosson, Michel

doi:10.1007/s11608-010-0348-4

Cited by 4 publications

(1 citation statement)

References 23 publications

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“…The contacts between the bodies are considered without friction. The laws of behaviour of organs and ligaments, which are based on our recent studies on the biomechanical behaviour of pelvic tissues, are considered to be a first approximation, as in large elastic transformations (Clay et al 2010;Rivaux et al 2010). …”

Section: Numerical Modelmentioning

confidence: 99%

Simulation of pelvic mobility: topology optimisation of ligamentous system

Vallet

Rubod²,

Witz

et al. 2011

Computer Methods in Biomechanics and Biomedical Engineering

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Section: Numerical Modelmentioning

confidence: 99%

Simulation of pelvic mobility: topology optimisation of ligamentous system

Vallet

Rubod²,

Witz

et al. 2011

Computer Methods in Biomechanics and Biomedical Engineering

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Modélisation biomécanique des mobilités des organes pelviens : vers une médecine personnalisée

Cosson

Rubod

Vallet

et al. 2011

Bulletin de l'Académie Nationale de Médecine

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Effects of Elastase Digestion on the Murine Vaginal Wall Biaxial Mechanical Response

Akintunde

Robison

Capone

et al. 2018

Journal of Biomechanical Engineering

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Although the underlying mechanisms of pelvic organ prolapse (POP) remain unknown, disruption of elastic fiber metabolism within the vaginal wall extracellular matrix (ECM) has been highly implicated. It has been hypothesized that elastic fiber fragmentation correlates to decreased structural integrity and increased risk of prolapse; however, the mechanisms by which elastic fiber damage may contribute to prolapse are poorly understood. Furthermore, the role of elastic fibers in normal vaginal wall mechanics has not been fully ascertained. Therefore, the objective of this study is to investigate the contribution of elastic fibers to murine vaginal wall mechanics. Vaginal tissue from C57BL/6 female mice was mechanically tested using biaxial extension–inflation protocols before and after intraluminal exposure to elastase. Elastase digestion induced marked changes in the vaginal geometry, and biaxial mechanical properties, suggesting that elastic fibers may play an important role in vaginal wall mechanical function. Additionally, a constitutive model that considered two diagonal families of collagen fibers with a slight preference toward the circumferential direction described the data reasonably well before and after digestion. The present findings may be important to determine the underlying structural and mechanical mechanisms of POP, and aid in the development of growth and remodeling models for improved assessment and prediction of changes in structure–function relationships with prolapse development.

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Caractérisation biomécanique des ligaments utérins. Implication en statique, en pelvienne

Cited by 4 publications

References 23 publications

Simulation of pelvic mobility: topology optimisation of ligamentous system

Simulation of pelvic mobility: topology optimisation of ligamentous system

Modélisation biomécanique des mobilités des organes pelviens : vers une médecine personnalisée

Effects of Elastase Digestion on the Murine Vaginal Wall Biaxial Mechanical Response

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