Capsule Endoscopy versus Push Enteroscopy in Patients with Occult Gastrointestinal Bleeding

Hartmann, Dirk; Schilling, Dieter; Bolz, Georg; Hahne, M; Jakobs, Ralf; Siegel, Emily; Weickert, U.; Adamek, Henning E.; Riemann, J F

doi:10.1055/s-2003-39330

Cited by 99 publications

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References 5 publications

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“…However, WCE has limitations: other endoscopic treatments such as biopsy or hemostasis are not possible, and the false negative rate remains high [ 15 ]. Complications including closure or massive hemorrhage require a clear diagnosis and treatment via surgery [ 16 ].…”

Section: Discussionmentioning

confidence: 99%

Congenital Jejunal Diverticular Bleeding in a Young Adult

et al. 2017

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Diverticular bleeding of the small bowel is rare and occurs primarily in adults aged more than 60 years. In younger adults, Meckel’s diverticulum, a true diverticulum that congenitally occurs in the distal ileum, is the most common cause of diverticular bleeding of the small bowel. Unlike Meckel’s diverticula, other kinds of small bowel diverticula are not congenital and their incidence is related to age. Furthermore, congenital true diverticular bleeding of the jejunum in adults is very rare. We report the case of a 24-year-old man with subepithelial tumor-like lesion accompanied with obscure overt gastrointestinal bleeding. This lesion was initially suspected to be a subepithelial tumor based on radiologic tests and capsule endoscopy. He was finally diagnosed with a congenital true diverticulum in the jejunum with the appearance of a Meckel’s diverticulum after surgical resection.

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Section: Discussionmentioning

confidence: 99%

Congenital Jejunal Diverticular Bleeding in a Young Adult

et al. 2017

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“…CE provides a higher diagnostic yield than barium contrast radiography of the small bowel or enteroscopy 1 2 3 4 . It is safe, painless, and well-tolerated 5 .…”

Section: Introductionmentioning

confidence: 99%

Lubiprostone improves visualization of small bowel for capsule endoscopy: a double-blind, placebo-controlled 2-way crossover study

et al. 2017

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Background and study aims Lubiprostone has been reported to be an anti-constipation drug. The aim of the study was to investigate the usefulness of lubiprostone both for bowel preparation and as a propulsive agent in small bowel endoscopy. Patients and methods This was a double-blind, placebo-controlled, 2-way crossover study of subjects who volunteered to undergo capsule endoscopy (CE). A total of 20 subjects (16 male and 4 female volunteers) were randomly assigned to receive a 24-μg tablet of lubiprostone 120 minutes prior to capsule ingestion for CE (L regimen), or a placebo tablet 120 minutes prior to capsule ingestion for CE (P regimen). Main outcome was gastric transit time (GTT) and small-bowel transit time (SBTT). Secondary outcome was adequacy of small-bowel cleansing and the fluid score in the small bowel. The quality of the capsule endoscopic images and fluid in the small bowel were assessed on 5-point scale. Results The capsule passed into the small bowel in all cases. Median GTT was 57.3 (3 – 221) minutes for the P regimen and 61.3 (10 – 218) minutes for the L regimen ( P = 0.836). Median SBTT was 245.0 (164 – 353) minutes for the P regimen and 228.05 (116 – 502) minutes for the L regimen ( P = 0.501). The image quality score in the small bowel was 3.05 ± 1.08 for the P regimen and 3.80 ± 0.49 for the L regimen ( P < 0.001). The fluid score in the small bowel was 2.04 ± 1.58 for the P regimen and 2.72 ± 1.43 for the L regimen ( P < 0.001). There was a significant difference between the 2 regimens with regard to image quality. The fluid score was more plentiful for the L regimen than for the P regimen. There were no cases of capsule retention or serious adverse events in this study. Conclusion Our study showed that use of lubiprostone prior to CE significantly improved visualization of the small bowel during CE as a result of inducing fluid secretion into the small bowel.

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Capsule and Small Bowel Endoscopy

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2015

Yamada' S Textbook of Gastroenterology

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Capsule Endoscopy versus Push Enteroscopy in Patients with Occult Gastrointestinal Bleeding

Cited by 99 publications

References 5 publications

Congenital Jejunal Diverticular Bleeding in a Young Adult

Congenital Jejunal Diverticular Bleeding in a Young Adult

Lubiprostone improves visualization of small bowel for capsule endoscopy: a double-blind, placebo-controlled 2-way crossover study

Capsule and Small Bowel Endoscopy

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