Capillary zone electrophoretic determination of the four vitamin C esters l-ascorbyl-2-phosphate, l-ascorbyl-2-sulfate, l-ascorbyl-2-diphosphate and l-ascorbyl-2-triphosphate in fish feed, plasma and tissue

Pauli, Niklaus; Schüep, Willy

doi:10.1016/s0378-4347(98)00264-3

Cited by 9 publications

(5 citation statements)

References 37 publications

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“…In conclusion, there is no evidence for vitamin C storage in the ester form in fish gametes (see also Pauli & Schuep 1998). Analytical inaccuracy in ascorbate estimation in fish gametes might have contributed to the difficulty of developing criteria for evaluating ascorbate status across fish taxa.…”

Section: Questions On Ascorbate Analysismentioning

confidence: 92%

Ascorbic acid and reproduction in fish: endocrine regulation and gamete quality

Dąbrowski

Ciereszko

2001

Aquaculture Research

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High ascorbic acid concentrations have been associated with gonad and brain tissues in teleost fishes. Although a direct dietary effect on gamete quality has been given some attention recently, the mechanism of action of ascorbate along the cascade of reproductive events in the hypothalamus, pituitary and gonads has not been defined. Data relating to gamete production and quality, as well as a possible protective role for ascorbate against cumulative genetic defects during gametogenesis and congenital malformation during gestation (embryonic development) is reviewed. It is suggested that the gonad growth in response to gonadotropin stimulation involves direct interaction between catecholamines and steroid hormones and their receptor sites. This interaction acts as a regulatory mechanism of ascorbate absorption, transfer and metabolism (degradation and/or renewal) in the reproductive system. We conclude that ascorbic acid is a leading nutrient in reproductive tissue functions and further research is needed on: (1) its antioxidant effect on gametes' (sperm and ova) capacity to prevent DNA damage occurring prior to (endogenous) and after spawning (environmental insults); (2) its dietary requirement to optimize survival and physiological recovery in multiple spawners; (3) the integration mechanism of ascorbic acid action as part of the overall endocrine regulation of neurohormonal–hormonal pathway in fish reproduction; and (4) the possible role for ascorbate in regulating fish maturation and/or infertility in the presence of enhanced UV‐radiation or conditions of intensive aquaculture (hypoxia, oxygen supersaturation, dietary pro–, and antioxidants).

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Section: Questions On Ascorbate Analysismentioning

confidence: 92%

Ascorbic acid and reproduction in fish: endocrine regulation and gamete quality

Dąbrowski

Ciereszko

2001

Aquaculture Research

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“…Analytical methods are available for the analysis of various L‐AA derivatives by HPLC15,350–352 and HPCE 353…”

Section: Analytical Methodologiesmentioning

confidence: 99%

PlantL-ascorbic acid: chemistry, function, metabolism, bioavailability and effects of processing

Davey

Montagu

Inzé

et al. 2000

J. Sci. Food Agric.

1,070

173

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Humans are unable to synthesise L‐ascorbic acid (L‐AA, ascorbate, vitamin C), and are thus entirely dependent upon dietary sources to meet needs. In both plant and animal metabolism, the biological functions of L‐ascorbic acid are centred around the antioxidant properties of this molecule. Considerable evidence has been accruing in the last two decades of the importance of L‐AA in protecting not only the plant from oxidative stress, but also mammals from various chronic diseases that have their origins in oxidative stress. Evidence suggests that the plasma levels of L‐AA in large sections of the population are sub‐optimal for the health protective effects of this vitamin. Until quite recently, little focus has been given to improving the L‐AA content of plant foods, either in terms of the amounts present in commercial crop varieties, or in minimising losses prior to ingestion. Further, while L‐AA biosynthesis in animals was elucidated in the 1960s,1 it is only very recently that a distinct biosynthetic route for plants has been proposed.2 The characterisation of this new pathway will undoubtedly provide the necessary focus and impetus to enable fundamental questions on plant L‐AA metabolism to be resolved. This review focuses on the role of L‐AA in metabolism and the latest studies regarding its biosynthesis, tissue compartmentalisation, turnover and catabolism. These inter‐relationships are considered in relation to the potential to improve the L‐AA content of crops. Methodology for the reliable analysis of L‐AA in plant foods is briefly reviewed. The concentrations found in common food sources and the effects of processing, or storage prior to consumption are discussed. Finally the factors that determine the bioavailability of L‐AA and how it may be improved are considered, as well as the most important future research needs. © 2000 Society of Chemical Industry

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“…Analytical methods are available for the analysis of various L-AA derivatives by HPLC 15,350±352 and HPCE. 353…”

Section: Analysis Of Ascorbate Derivativesmentioning

confidence: 99%

Plant L‐ascorbic acid: chemistry, function, metabolism, bioavailability and effects of processing

Davey

Montagu

Inzé

et al. 2000

J. Sci. Food Agric.

465

612

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Humans are unable to synthesise L-ascorbic acid (L-AA, ascorbate, vitamin C), and are thus entirely dependent upon dietary sources to meet needs. In both plant and animal metabolism, the biological functions of L-ascorbic acid are centred around the antioxidant properties of this molecule. Considerable evidence has been accruing in the last two decades of the importance of L-AA in protecting not only the plant from oxidative stress, but also mammals from various chronic diseases that have their origins in oxidative stress. Evidence suggests that the plasma levels of L-AA in large sections of the population are sub-optimal for the health protective effects of this vitamin.Until quite recently, little focus has been given to improving the L-AA content of plant foods, either in terms of the amounts present in commercial crop varieties, or in minimising losses prior to ingestion. Further, while L-AA biosynthesis in animals was elucidated in the 1960s, 1 it is only very recently that a distinct biosynthetic route for plants has been proposed. 2 The characterisation of this new pathway will undoubtedly provide the necessary focus and impetus to enable fundamental questions on plant L-AA metabolism to be resolved.This review focuses on the role of L-AA in metabolism and the latest studies regarding its biosynthesis, tissue compartmentalisation, turnover and catabolism. These inter-relationships are considered in relation to the potential to improve the L-AA content of crops. Methodology for the reliable analysis of L-AA in plant foods is brie¯y reviewed. The concentrations found in common food sources and the effects of processing, or storage prior to consumption are discussed. Finally the factors that determine the bioavailability of L-AA and how it may be improved are considered, as well as the most important future research needs.

show abstract

Capillary zone electrophoretic determination of the four vitamin C esters l-ascorbyl-2-phosphate, l-ascorbyl-2-sulfate, l-ascorbyl-2-diphosphate and l-ascorbyl-2-triphosphate in fish feed, plasma and tissue

Cited by 9 publications

References 37 publications

Ascorbic acid and reproduction in fish: endocrine regulation and gamete quality

Ascorbic acid and reproduction in fish: endocrine regulation and gamete quality

PlantL-ascorbic acid: chemistry, function, metabolism, bioavailability and effects of processing

Plant L‐ascorbic acid: chemistry, function, metabolism, bioavailability and effects of processing

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