Capacity differences in working memory based on resting state brain networks

Osaka, Mariko; Kaneda, Mizuki; Azuma, Miyuki; Yaoi, Ken; Shimokawa, Tetsuya; Osaka, Naoyuki

doi:10.1038/s41598-021-98848-2

Cited by 5 publications

(2 citation statements)

References 55 publications

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“…The importance of the frontal cortex was also suggested in our previous study (Osaka et al, 2021), which investigated individual differences in WM capacity based on brain RSN. Additionally, our investigation revealed that capacity differences in working memory, assessed through a reading span test, which is one of the complex span tests, are linked to differences in the strength of RSN connectivity in the brain.…”

Section: Discussionmentioning

confidence: 68%

The arousal level of consciousness required for working memory performance: An anaesthesia study

Osaka,

Minamoto,

Ikeda

et al. 2024

Eur J of Neuroscience

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Regarding the stage of arousal level required for working memory to function properly, limited studies have been conducted on changes in working memory performance when the arousal level of consciousness decreases. This study aimed to experimentally clarify the stages of consciousness necessary for optimal working memory function. In this experiment, the sedation levels were changed step‐by‐step using anaesthesia, and the performance accuracy during the execution of working memory was assessed using a dual‐task paradigm. Participants were required to categorize and remember words in a specific target category. Categorization performance was measured across four different sedative phases: before anaesthesia (baseline), and deep, moderate and light stages of sedation. Short‐delay recognition tasks were performed under these four sedative stages, followed by long‐delay recognition tasks after participants recovered from sedation. The results of the short‐delay recognition task showed that the performance was lowest at the deep stage. The performance of the moderate stage was lower than the baseline. In the long‐delay recognition task, the performance under moderate sedation was lower than that under baseline and light sedation. In addition, the performance under light sedation was lower than that under baseline. These results suggest that task performance becomes difficult under half sedation and that transferring information to long‐term memory is difficult even under one‐quarter sedation.

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Section: Discussionmentioning

confidence: 68%

The arousal level of consciousness required for working memory performance: An anaesthesia study

Osaka,

Minamoto,

Ikeda

et al. 2024

Eur J of Neuroscience

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“…Therefore, this part of the brain is probably important for ASD pathophysiology. As we know that the dorsolateral prefrontal cortex plays an important role in executive function by connecting the frontal and parietal cortices via frontoparietal networks ( Haber et al, 2021 ), enhancing working memory capacity ( Osaka et al, 2021 ), and is related to human intelligence ( Hearne et al, 2016 ). An irregular arrangement of neural connections is one of the proposed pathologies of ASD.…”

Section: Discussionmentioning

confidence: 99%

Brain laterality evaluated by F-18 fluorodeoxyglucose positron emission computed tomography in autism spectrum disorders

Keeratitanont

Theerakulpisut

Auvichayapat

et al. 2022

Front. Mol. Neurosci.

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Background and rationaleAutism spectrum disorder (ASD) is a neuropsychiatric disorder that has no curative treatment. Little is known about the brain laterality in patients with ASD. F-18 fluorodeoxyglucose positron emission computed tomography (F-18 FDG PET/CT) is a neuroimaging technique that is suitable for ASD owing to its ability to detect whole brain functional abnormalities in a short time and is feasible in ASD patients. The purpose of this study was to evaluate brain laterality using F-18 FDG PET/CT in patients with high-functioning ASD.Materials and methodsThis case-control study recruited eight ASD patients who met the DSM-5 criteria, the recorded data of eight controls matched for age, sex, and handedness were also enrolled. The resting state of brain glucose metabolism in the regions of interest (ROIs) was analyzed using the Q.Brain software. Brain glucose metabolism and laterality index in each ROI of ASD patients were compared with those of the controls. The pattern of brain metabolism was analyzed using visual analysis and is reported in the data description.ResultsThe ASD group’s overall brain glucose metabolism was lower than that of the control group in both the left and right hemispheres, with mean differences of 1.54 and 1.21, respectively. We found statistically lower mean glucose metabolism for ASD patients than controls in the left prefrontal lateral (Z = 1.96, p = 0.049). The left laterality index was found in nine ROIs for ASD and 11 ROIs for the control. The left laterality index in the ASD group was significantly lower than that in the control group in the prefrontal lateral (Z = 2.52, p = 0.012), precuneus (Z = 2.10, p = 0.036), and parietal inferior (Z = 1.96, p = 0.049) regions.ConclusionIndividuals with ASD have lower brain glucose metabolism than control. In addition, the number of ROIs for left laterality index in the ASD group was lower than control. Left laterality defects may be one of the causes of ASD. This knowledge can be useful in the treatment of ASD by increasing the left-brain metabolism. This trial was registered in the Thai Clinical Trials Registry (TCTR20210705005).

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Greater interruption of visual processing and memory encoding by visceral than somatic pain in healthy volunteers – An fMRI study

Schmidt¹,

Kleine-Borgmann²,

Scharmach³

et al. 2022

NeuroImage

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Capacity differences in working memory based on resting state brain networks

Cited by 5 publications

References 55 publications

The arousal level of consciousness required for working memory performance: An anaesthesia study

The arousal level of consciousness required for working memory performance: An anaesthesia study

Brain laterality evaluated by F-18 fluorodeoxyglucose positron emission computed tomography in autism spectrum disorders

Greater interruption of visual processing and memory encoding by visceral than somatic pain in healthy volunteers – An fMRI study

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