Capacité de la biopsie de la prostate à prédire le score réel du cancer de la prostate?

Dehayni, Y.; Habibi, Hengameh; Balla, Bouzid; Abiad, Yassine El; Ammani, A.; Qarro, A.; Alami, M.

doi:10.1016/j.afju.2016.02.002

Cited by 4 publications

(3 citation statements)

References 15 publications

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“…The mean age of our patients was 72,43 years with extreme values ranging from 56 to 86 years old. These epidemiological findings were similarly reported by various other authors [4][5][6].…”

Section: Discussionsupporting

confidence: 90%

Evaluation of the effectiveness of the prostate biopsy at the Saint Jean De Dieu Hospital of Tanguieta

KF,

et al. 2023

Int J Res Oncol

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Introduction: Prostate cancer is the most common and the second leading cause of cancer death in men in most developed countries. Prostate biopsy remains the gold standard to confirm its diagnosis. Material and Method: This is a prospective study during 6 months, starting from 1st of February to 31st of July 2022. It included all patients who underwent a prostate biopsy that was carried out either following a high tPSA or due to an abnormal digital rectal examination. Results: We performed digitally guided biopsies in 32 patients from whom, average age was 72.43 years and elevation of total PSA was the main reason (71.88%) behind biopsies. The mean total PSA level was 45.69 ng/ml. The tissues removed were essentially prostate tissues, malignant in 28.12% of cases with adenocarcinoma as the only histological type. Conclusion: Prostate biopsy remains the gold standard for the diagnosis of prostate cancer. When indicated in front of an abnormal digital rectal examination, the probabilities of positivity of the samples are high even in the case of digitally guided biopsies in an under-equipped environment.

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Section: Discussionsupporting

confidence: 90%

Evaluation of the effectiveness of the prostate biopsy at the Saint Jean De Dieu Hospital of Tanguieta

KF,

et al. 2023

Int J Res Oncol

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“…The Qarro study finds an average age of 62.8 years [2], the Boccon-Gibod series [3] (63.8 years), the Seong Cheol et al [4] study (64.4 years), the Khiari and al study [5] (67 years) and that of Peko et al [6] (69 years). The average PSA in our study was 11 ng/mL, and it was lower than in the Carolina study (7.83 ng mL) [7] and higher than in the Dehayni study (15.17 ng/ml) [8]. The recommended number of biopsies was 12, and this number can increase in the presence of suspicious foci or can be lower in the case of small prostates.…”

Section: Discussioncontrasting

confidence: 65%

Pathological correlation between prostate biopsies and the radical prostatectomy, about 30 cases

et al. 2021

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Background Since the advent of the massive prostate-specific antigen (PSA) testing, prostate cancer has become a major public health problem. It is currently the most common cancer and the second leading cause of cancer death in men. The diagnosis is based on the histopathological study of prostate biopsies. The aim of our work was to study the correlation of the grade group (GG) using the ISUP 2016 classification between the prostate needle biopsies and radical prostatectomy specimen. Methods This was a retrospective study of 30 patients. We studied the correlation of the grade group (GG) according to the new classification ISUP (2016) between prostate biopsies and radical prostatectomy specimen. Results The average age of our patients was 65 years, the diagnosis was discovered on an individual screening in 15% of the cases, and 65% of our patients were diagnosed with LUTS due to an associated benign prostatic hyperplasia. The average PSA level in our study was 11 ng/ml. In the biopsies group, the grade 1 and 2 groups were in the majority with 40% of the cases each of them. We noted that GG 3 (Gleason 4 + 3) was represented in 16.66% of cases, while GG4 was only present in 3% of cases. On the prostatectomy specimen group, GG1 was represented in 33.33% of cases, GG2 in 40% of cases and GG3 in 20% of cases. GG4 was represented in 6.66% of cases. Among GG1 patients, identical staging was noted in 75% of cases, and under-staging in 25% of cases. For GG2 patients, over-staging in 8.3% of cases, identical staging in 83.3% of cases and under-staging of 8.3%. Among GG 3 patients, there was an 80% identical staging, while an under-staging was present in 20% of cases. The GG 4 is perfectly correlated. Combining all groups in our study, we noted an exact staging in 80% of the cases, an under-staging in 16.33% of the cases, and an over-staging in 3.33% of the cases. The Kappa concordance index was 0.4. Conclusions The correlation of the grade group between the prostate biopsies and the radical prostatectomy specimen was imperfect; the more the cancer increases in the grade group, the better was the correlation.

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“…In 34.3% of the cases, it was an adenocarcinoma of the prostate. Most patients (41.7%) had a moderately diffe- [23] and Kévin in France [24], found respectively 40%, 57.4% and 58% of well-differentiated tumors.…”

Section: Discussionmentioning

confidence: 95%

Epidemiological, Clinical, Paraclinical and Therapeutic Profile of Prostate Tumors at Panzi Hospital, Democratic Republic of the Congo

John,

Cikwanine,

Bafunyembaka

et al. 2023

OJU

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Tumor pathologies of the prostate gland are represented by benign prostate tumor and prostate cancer and are generally seen after 50 years. The objective of this work was to study the epidemiological, clinical, paraclinical and therapeutic aspects of prostate tumors at the General Reference Hospital of Panzi (DRC). Patients and Methods: Retrospective cross-sectional study on 70 patients followed in hospital or on an outpatient basis for prostate tumor in the urology department of the General Reference Hospital of Panzi from January 1, 2013 to December 31, 2017. The epidemiological, clinical and paraclinical parameters (pathology with Gleason score, prostate volume on ultrasound, urinary impact on ultrasound, urea level, creatinine level and PSA level) and therapeutics were studied. Results: Prostate tumors represent 3.84% of surgical pathologies. The average age of the patients was 68.2 years with the extremes of 47 and 90 years old. The patients were transferred in 78.6% of the cases. Acute urine retention was the most common reason for consultation with 42.8%. The PSA rate > 4 ηg in 92.9% of the cases. Benign prostatic hyperplasia was found in 62.8% of patients against 35.7% of prostate adenocarcinoma and 41.7% of prostate cancers were moderately differentiated. The prostate volume was 41 -60 g in 35.7% of the cases. No urinary impact in 71.4% of patients. Surgical treatment was in 85.7% and RTUP was the most used at 40%. A hospital stay between 15 and 21 days in 30% of cases. The cure rate was 81.4% and 14.3% developed urethral stenosis. Conclusion: Prostate tumors are common in people over the age of 50 who see for acute retention of urine. Benign enlarged prostate is the most common.

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Capacité de la biopsie de la prostate à prédire le score réel du cancer de la prostate?

Cited by 4 publications

References 15 publications

Evaluation of the effectiveness of the prostate biopsy at the Saint Jean De Dieu Hospital of Tanguieta

Evaluation of the effectiveness of the prostate biopsy at the Saint Jean De Dieu Hospital of Tanguieta

Pathological correlation between prostate biopsies and the radical prostatectomy, about 30 cases

Epidemiological, Clinical, Paraclinical and Therapeutic Profile of Prostate Tumors at Panzi Hospital, Democratic Republic of the Congo

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