Cannabis et syndromes coronariens aigus avec sus-décalage de ST

Ghannem, M.; Belhadj, I.; Tritar, A.; Moukala, T.; Amri, N. El; Noury, A.; Zaghdoudi, M.

doi:10.1016/j.ancard.2013.09.002

Cited by 13 publications

(2 citation statements)

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“…Additionally, review articles refer to the first hour after cannabis smoking as the riskiest hour, with the risk falling rapidly thereafter . Several authors have reported cases of CVD in proximity to cannabis use, sometimes supported by a positive urinalysis, as reported in Table . However, a positive cannabis finding is common up to 5 days after smoking and, in heavy smokers, positivity may be present for weeks or months .…”

Section: Introductionmentioning

confidence: 99%

Coronary thrombosis and marijuana smoking: a case report and narrative review of the literature

Marchetti

Matteis

et al. 2015

Drug Testing and Analysis

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We encountered evidence of myocardial infarction due to coronary thrombosis in an autopsy of an occasional marijuana smoker. These findings prompted us to perform a narrative review of the literature to determine when post-mortem toxicological tests may support a temporal relationship between marijuana smoking and cardiovascular disease. Toxicological examination showed the presence of Δ-9-tetrahydrocannabinol, its main metabolite and cannabinol in blood and urine. Quali-quantitative analysis revealed that Δ-9-tetrahydrocannabinol was taken within 2 h of the onset of cardiovascular symptoms, according to circumstantial data. Post-mortem toxicological results must take into account the degradation and post-mortem redistribution of analytes. However, for any inference about the specific cardiovascular triggering effect of Δ-9-tetrahydrocannabinol intake, we maintain that cannabinoid analysis in blood samples must be considered an essential requirement to estimate the time of last intake and avoid incomplete documentation. The literature, combined with the present case report, highlights an association between marijuana use and negative cardiovascular events, although few authors have supported their conclusions with toxicological results. Thus, additional research is needed.

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Section: Introductionmentioning

confidence: 99%

Coronary thrombosis and marijuana smoking: a case report and narrative review of the literature

Marchetti

Matteis

et al. 2015

Drug Testing and Analysis

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“…Casier et al [3] reported that cannabis abuse was associated with severe coronary syndrome due to coronary spasm and MI with a total artery occlusion. Deharo et al [10], Ghannem et al [11], and Yurtdaş et al [12] reported cases of excessive cannabis use induced MI after an exercise in healthy young men with a thrombotic occlusion. Finally it is still obscure, if cannabis contributes to coronary diseases in the same way as smoking [13], but these case studies indicate that cannabis can be a risk factor for MI in addicted persons.…”

Section: Discussionmentioning

confidence: 99%