“…interleukin (IL)-4, IL-10) [190,191,23] and inhibit production of pro-inflammatory cytokines (e.g. IL-1β, IL-6, IL-8, tumour necrosis factor (TNF)-α) [10,50,55,62,63,113,130,149,154,186] and reactive oxygen species [62,130,186]. Models demonstrating such effects have included lung injury induced by chemical treatment [149] and hypoxic-ischemia (HI) [10]; liver injury induced by ischemia-reperfusion [63,130] and alcohol feeding [186]; myocardial [55] and renal [62] ischemia-reperfusion injuries; surgically induced oral lesions [102]; chemically induced osteoarthritis [145]; spinal cord contusion injury [113], and colitis [23,50,154] (see Burstein [24] for review).…”