Canine ehrlichiosis in the Ivory Coast and Gabon: alteration of biochemical blood parameters based on Ehrlichia canis serology

Correlation between canine biochemical analytes and TRP36 ELISA seropositivity for Ehrlichia canis in Brazil

“…Dogs infected with the subclinical disease or asymptomatic chronic stage of CME may be considered reservoirs for the pathogen, and protein alterations such as hyperproteinemia, hyperglobulinemia, and hypoalbuminemia are important indicators of the infection, regardless of the stage in which the dog is occurring. 7,8 Mild increases in alanine aminotransferase (ALT) and alkaline phosphatase (ALP) are more frequent in dogs during the acute phase than during the chronic phase of the infection. [9][10][11] On the other hand, increases in urea and creatinine enzyme levels are observed during the chronic phase due to the deposition of immune complexes in the glomeruli, which can cause kidney damage.…”