Canine and feline parasitic zoonoses in China

Chen, Jia; Xu, Min-Jun; Zhou, Dong‐Hui; Song, Hui-Qun; Wang, Chun-Ren; Zhu, Xing‐Quan

doi:10.1186/1756-3305-5-152

Cited by 93 publications

(71 citation statements)

References 68 publications

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“…As described by Zewdu et al [25], 50% of the necrosed dogs in Ambo, Ethiopia, were found to be positive for A. caninum. According to Chen et al [26], although A. caninum and A. tubaeforme have been documented to be the most common species occurring in the warmer ranges of China, A. caninum is also prevalent in the cold regions of the country. Szabova et al [4] also demonstrate a high prevalence of nematodes from the Ancylostomatidae family in dog populations from 2 shelters located in the Slovak Republic, the exact values being 25.6% and 26.8%.…”

Section: Discussionmentioning

confidence: 99%

Stray dogs and cats as potential sources of soil contamination with zoonotic parasites

Szwabe¹,

Błaszkowska²

2017

Ann Agric Environ Med.

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Szwabe K, Błaszkowska J. Stray dogs and cats as potential sources of soil contamination with zoonotic parasites. Ann Agric Environ Med. 2017; 24(1): 39-43. doi: 10.5604/12321966.1234003 Abstract Introduction and objective. The main source of many zoonoses is soil contaminated with feline and canine faeces. Thus, the aim of this study was to estimate the prevalence of intestinal parasites in stray dogs and cats adopted in Lodz shelter (Poland). Materials and methods. In total, 163 faecal samples were collected from 95 dogs and 68 cats from 2011 to 2012. The samples were processed by sedimentation techniques using Mini Parasep®SF. Results. Six parasite genera belonging to protozoa, cestoda, and nematoda, were found in dogs, while eight were found in cats. Out of the 163 fecal samples, 37.4% were positive for the presence at least one species of intestinal parasites. The majority of positive dog samples contained eggs from Toxocara and Trichuris genera, and the family Ancylostomatidae, while Toxocara and Taenia eggs, as well as Cystoisospora oocysts, predominated in cat faeces. A significantly higher prevalence of parasites was noted in cats (48.5%) than in dogs (29.5%) (χ 2 =6.15, P=0.013). The Toxocara genus was the most prevalent parasite in both populations; eggs were found in 27.9% and 16.8% of cats and dogs, respectively. Animals younger than 12 months of age showed higher infection rates with Toxocara, but differences were not statistically significant. The average numbers of Toxocara eggs/gram of faeces in positive puppy and kitten samples were over 5 and 7 times higher than in older dogs and cats, respectively. Mixed infection were found in dogs (5.3%) and cats (8.8%). Conclusions. Cat faeces represent a more important potential source of environmental contamination with zoonotic parasites than dog faeces. Among the detected parasites of stray dogs and cats, Toxocara present an important zoonotic risk for the local human population, especially children.

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Section: Discussionmentioning

confidence: 99%

Stray dogs and cats as potential sources of soil contamination with zoonotic parasites

Szwabe¹,

Błaszkowska²

2017

Ann Agric Environ Med.

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“…As an obligate intracellular protozoan pathogen, Toxoplasma gondii has worldwide distribution and can invade virtually all warm-blooded animals and humans, leading to toxoplamosis, an important zoonotic parasitic disease, and thus causes serious public safety issues (Montoya and Liesenfeld, 2004;Chen et al, 2012a;Tian et al, 2012;Zhang et al, 2013). Although T. gondii infections in immunocompetent individuals are subclinical or usually asymptomatic, the infection can cause severe clinical problem or death in immunosuppressed and immunodeficient individuals, such as Toxoplasma encephalitis (TE) or neurological lesions (Montoya and Liesenfeld, 2004;Weiss and Dubey, 2009;Dubey, 2010).…”

Section: Introductionmentioning

confidence: 99%

Characterization of the Toxoplasma gondii hsp60 gene sequences from different hosts and geographical locations

et al. 2014

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ABSTRACT. The intracellular protozoan Toxoplasma gondii is one of the most successful parasites, with the ability to invade all warmblooded animals, including humans. T. gondii heat shock protein 60 (TgHSP60) plays an important role in intracellular survival and in the differentiation of the parasite, and is also recognized as being associated with its virulence. In the present study, we examined sequence variation in the hsp60 coding region among five T. gondii isolates from different hosts and geographical regions, which were compared with the corresponding sequences of strains ME49, 76K, and GT1 available in the ToxoDB databases. The length of the T. gondii hsp60 sequence was 1728 bp for all strains, and the A+T content ranged from 41.96 to 42.13%. The sequence alignment of the 8 T. gondii strains identified 20 variable positions (0-1.44%) and showed 1.16% overall sequence 6907 ©FUNPEC-RP www.funpecrp.com.br Genetics and Molecular Research 13 (3): 6906-6911 (2014) Sequence variation in the T. gondii hsp60 gene variation, suggesting a relatively considerable sequence diversity. Phylogenetic analysis of hsp60 sequences using Bayesian inference and maximum parsimony differentiated the two major clonal lineage types into their respective clusters, and thus separated atypical strains from classical genotypes. The results of the present study suggested that the coding region of the hsp60 gene may represent a novel genetic marker for intraspecies phylogenetic analyses of T. gondii.

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“…It has been claimed that about 85% of these people are in China [1][2][3]. Such disease is characterized by cholangitis with remarkable recruiting inflammatory cells in the early stage of infection, followed by hyperplasia of the intrahepatic bile ducts, cholangiofibrosis, and cholelithiasis in the host liver during the chronic stage [4].…”

Section: Introductionmentioning

confidence: 99%

Expression of Toll-like receptor (TLR) 2 and TLR4 in the livers of mice infected by Clonorchis sinensis

Yan

et al. 2015

J Infect Dev Ctries

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Introduction: Clonorchis sinensis is one of the most important foodborne pathogens in humans, and can cause biliary diseases such as gallstones, cholecystitis, cholangitis, and cholangiocarcinoma. Toll-like receptors (TLRs) as sensors are crucial to initiating both innate and adaptive immune defenses against pathogens. However, little is known about the hepatic expression of TLRs of hosts induced by C. sinensis infection. Methodology: In the present study, the expression and distribution of TLR2 and TLR4 were investigated in a mouse model of clonorchiasis on days 28, 56, 84, and 112 post-infection (PI) using real-time quantitative reverse transcription polymerase chain reaction (PCR) and immunohistochemically staining, respectively. The levels of cytokines that are mediated by TLR2 and TLR4 were also evaluated using a cytometric bead array. Results: Results showed that the transcripts of TLR2 and TLR4 were upregulated on day 28 PI in C. sinensis-infected mice compared with non-infected ones (p < 0.01). In addition, their proteins were strongly immunohistochemically positive in the cytoplasm and membrane of endothelial cells, fibroblasts, and biliary epithelium cells of C. sinensis-infected mice. The levels of interleukin (IL)-4, IL-10, tumor necrosis factor alpha (TNF-α) and interferon gamma (IFN-γ) were increased with activation of TLR2 and TLR4. Conclusions: The expression of TLR2 and TLR4 is upregulated against C. sinensis infection, which suggests that TLR2 and TLR4 might be involved in immune responses during C. sinensis infection.

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Canine and feline parasitic zoonoses in China

Cited by 93 publications

References 68 publications

Stray dogs and cats as potential sources of soil contamination with zoonotic parasites

Stray dogs and cats as potential sources of soil contamination with zoonotic parasites

Characterization of the Toxoplasma gondii hsp60 gene sequences from different hosts and geographical locations

Expression of Toll-like receptor (TLR) 2 and TLR4 in the livers of mice infected by Clonorchis sinensis

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