Candida polyarthritis in a renal transplant patient: case report of a patient successfully treated with amphotericin B

Candida parapsilosis Septic Arthritis in a Renal Transplant Patient

“…The prevalence increases during fungal encouraging conditions such as immune-suppressed hosts, granulocytopenia, exposure to broad spectrum antibiotics, hyperalimentation via indwelling central intravascular catheters, multiple abdominal surgery, malnutrition, corticosteroid therapy, and drug abuse. [1][2][3] Two clinical patterns of fungal arthritis are known: an acute-onset type with synovial and systemic symptoms and usually an early diagnosis and a mild chronic course type with little pain and few articular and systemic symptoms, leading to a diagnostic delay that can last for several years. 1 Weight-bearing joints, especially the knees, are the most infected sites during both fungal and bacterial septic arthritis.…”

“…1 Weight-bearing joints, especially the knees, are the most infected sites during both fungal and bacterial septic arthritis. 2 The source of the fungal infection seems to be blood stream based on the assumption that the spreading to 2 separate organs (perinephric and synovial fluids) must be blood borne in the existence of so many predisposing factors.…”