Cancerous tissues analyzed by SRIXE

Trace elements in human cancerous and healthy tissues: A comparative study by EDXRF, TXRF, synchrotron radiation and PIXE

“…SRIXE was also used to prove the implication of trace elements in the carcinogenesis of the prostate. Higher concentration for the elements Mn, Fe, Co and Ni, was detected in the cancerous regions of the tissues in comparison with healthy ones [10]. This study connected the development of the prostate cancer with the amount of Fe, Cu and Zn.…”

“…W.M. Kwiatek et al [10] report an increase of Mn, Ni and Co levels in cancerous tissues. A steady ratio of Zn/Cu was also observed which leads to an association of both elements on the advance of prostate cancer (see Table 5).…”

Distribution of selected elements in atherosclerotic plaques of apoE/LDLR‐double knockout mice assessed by synchrotron radiation‐induced micro‐XRF spectrometry

“…Synchrotron radiation-induced x-ray fluorescence (XRF) was successfully applied to examine histological sections derived from neoplasms, degenerative lesions of the central nervous system and others. 6,7 The use of this technique in atherosclerosis research was limited to 3-D imaging of vessels involved in the pathological processes. 8 In the present study, we have combined synchrotron radiation micro-XRF spectrometry with a complete set of histological stainings to determine localization and concentration of selected elements in histologically defined areas of atherosclerotic lesions in aortic roots of apoE/LDLR / mice.…”

Near‐field laser ablation inductively coupled plasma mass spectrometry: a novel elemental analytical technique at the nanometer scale

“…Synchrotron radiation‐induced X‐ray emission (SRIXE)18 that utilizes far‐field diffraction imaging with coherent illumination (allowing the resolution limit to be overcome by reconstructing the electron density of the object using phase retrieval techniques) has been established as a powerful imaging method. Recently, Kwiatek et al 19. used a highly coherent X‐ray source (at HASYLAB/DESY, Hamburg, Germany) to determine elemental concentrations (Mn, Fe, Co, Ni) in tumor tissues.…”