Cancer Surgery in the Elderly

Kemeny, Margaret; Busch-Devereaux, Erna; Merriam, Louis T.; O’Hea, Brian

doi:10.1016/s0889-8588(05)70283-5

Cited by 57 publications

(30 citation statements)

References 107 publications

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“…Besides second malignancies, many other factors such as comorbidity, decreased functional status, alterations in mental status and an assumed inability to tolerate treatment are all factors that may influence the selection of therapy and thus may affect survival of the elderly [20].…”

Section: Discussionmentioning

confidence: 99%

“…For the evaluation of elderly patients, cutoffs at 65, 70 or 75 years are common in the literature, [10,12,15,18,19]. The \70 vs. C70 year cutoff was chosen because it is also used for risk assessment in surgery [20,21]. In addition, survival was examined in age groups of 10 years between the 50th and 80th year to provide further detailed information about the effects of age.…”

Section: Munich Cancer Registry 1998-2012mentioning

confidence: 99%

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Outcome of gastric cancer in the elderly: a population-based evaluation of the Munich Cancer Registry

et al. 2015

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Background Gastric cancer accounts for 5 % of cancer deaths. Proportions of older stomach cancer patients are increasing. Despite the still poor prognosis, standardised treatment has achieved improvements; nonetheless it is questionable whether all age groups have benefitted. Age and outcome need to be examined in a population-based setting. Methods Analyses included Munich Cancer Registry (MCR) data from 8601 invasive gastric cancer patients, diagnosed between 1998 and 2012. Tumour and therapy characteristics and outcome were analysed by two age groups (\70 vs. C70 years). Survival was analysed using the Kaplan-Meier method and relative survival was computed as an estimation for cancer-specific survival.Additional landmark analyses were conducted by calculating conditional survival of patients who survived more than 6 months. Results Fifty-nine per cent of the cohort were C70 years old. These patients had tumours with a slightly better prognosis and were treated with less radical surgery and adjuvant therapy than younger patients. The 5-year relative survival was 40 % for the youngest (\50 years) and 23 % for the oldest patients (C80 years). Survival differences were diminished or eliminated after landmark analyses:The 5-year relative survival in age groups 50-59, 60-69 and 70-79 years was comparable (between 48 and 49.6 %) and slightly worse in the youngest and oldest (45 %), which may be explained by more aggressive tumours and effects of cellular senescence, respectively. Conclusion 123Gastric Cancer (2016( ) 19:713-722 DOI 10.1007 resection and chemotherapy, it is conducted and the result is comparable between age groups.

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Section: Discussionmentioning

confidence: 99%

Section: Munich Cancer Registry 1998-2012mentioning

confidence: 99%

Outcome of gastric cancer in the elderly: a population-based evaluation of the Munich Cancer Registry

et al. 2015

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“…A burgeoning literature suggests that surgery in healthy elderly women is safe and without additional risk compared with their younger counterparts. 31 Breast-conserving therapy (lumpectomy, axillary dissection, breast irradiation) has now been shown to be equal in efficacy to more extensive surgical options with no significant differences in overall 20-year survival. 32,33 Data suggest that elderly women are less likely to be offered or receive breast conservation surgery, with 25% of women aged 80 or older receiving breast preservation compared with 42% of women under 50 years of age.…”

Section: Surgical Options and Considerations In The Elderly Patientmentioning

confidence: 99%

Diagnosis and Treatment of Breast Cancer in the Elderly

Holmes

Muss

2003

CA: A Cancer Journal for Clinicians

105

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As the population of the United States ages, women over the age of 65 have become a prominent cohort in the breast cancer population, with approximately 50% of all new breast cancers occurring in women aged 65 years and older. Early studies in breast cancer often excluded women based on age or comorbidity, leaving physicians and patients with a growing number of diagnostic and treatment options, each of which often carry short-term morbidity risks for potential long-term gain. We review the current data available for diagnosis and treatment of elderly women with breast cancer in both the adjuvant and metastatic disease setting. In addition, the role of screening and new concepts in prevention are discussed with emphasis on the older patient. (CA Cancer

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“…Aun cuando se sabe que la morbilidad y la mortalidad de las complicaciones postoperatorias aumentan con la edad (46), sin embargo los riesgos aumentan principalmente en cirugía urgente (31,47), lo que en parte traduce que los pacientes mayores se manifiestan menos clínica-mente (48), o que su diagnóstico se retrasa a estadios más avanzados de la enfermedad (49). En general es admitido que excepto para el cáncer de próstata, la cirugía es el principal arma de tratamiento de los cánceres sólidos (21).…”

Section: Cirugíaunclassified

Prevalencia y tratamiento de la patología oncológica en el anciano: El reto que se avecina

Portilla¹,

Lecea²,

Cendoya³

et al. 2008

Rev. esp. enferm. dig.

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RESUMENLa esperanza media de vida en España se ha más que duplicado a lo largo del siglo XX, llegando en la actualidad a 75 años en el varón y 83 años en la mujer. Las predicciones de la evolución y crecimiento poblacional a nivel mundial y nacional auguran un shock demográfico cuando en España el número de mayores de 65 años alcance el 33,5% de la población en el 2050.Es conocido que el cáncer está intrínseca y directamente relacionado con la edad, siendo una patología de personas mayores, ya que al menos el 60% de ellos aparecen en mayores de 65 años. Los ancianos constituyen el grupo más importante de la práctica oncológica médica. Las predicciones de envejecimiento de la población española, permiten intuir que el cáncer en el anciano y su tratamiento deba ser considerado un problema sanitario de primer orden.El cáncer ya no es sinónimo de muerte para la mayoría de los pacientes. Globalmente el 60% se curan o cronifican. Esta mejora pronóstico tiene un precio tanto en las expectativas de tratamiento como de posterior seguimiento y mantenimiento de las secuelas que pueden generarse.El mayor y mejor conocimiento y comprensión del proceso de envejecimiento, permitirá identificar y seleccionar aquellos pacientes mayores que pueden beneficiarse de medidas de prevención y tratamiento, y lo más importante permitirá identificar aquellos pacientes que no son candidatos de tratamientos con intención curativa por tratarse de población frágil.Los adelantos en el campo de la cirugía, especialmente en la cirugía mínimamente invasiva y su aplicación al campo de la cirugía oncológica, permiten prever que un mayor número de pacientes ancianos podrán beneficiarse de un tratamiento con intención curativa. La edad no prevendrá de tratamientos apropiados en individuos ancianos con cáncer, especialmente aquellos en los que tengan una adecuada expectativa de vida y reserva funcional. Combatir esta discriminación sanitaria constituye una de las principales prioridades en la estrategia para el mantenimiento de la salud del anciano. ABSTRACTLife expectancy in Spain has more than duplicated during the last 20 th Century, and is currently 75 years for men and 83 years for women. Predictions on the evolution of the National and global population anticipate a demographic shock in Spain when individuals older than 65 years eventually make up more than 33.5% of the Spanish population by year 2050.It is known that cancer is directly related with age, and that it is a disease of older people -at least 60% of all cancers are diagnosed in patients older than 65 years. The older people group is the most important group of patients in oncologic practice today. Predictions on the aging of the Spanish population show that cancer in the aging patient and its treatment must be considered a first-line health problem. The diagnosis of cancer is not associated with death in the majority of patients. Sixty percent of cancers are globally cured or chronified. This advanced prognosis has its toll not only in the expectancy of treatment but also in subseque...

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Cancer Surgery in the Elderly

Cited by 57 publications

References 107 publications

Outcome of gastric cancer in the elderly: a population-based evaluation of the Munich Cancer Registry

Outcome of gastric cancer in the elderly: a population-based evaluation of the Munich Cancer Registry

Diagnosis and Treatment of Breast Cancer in the Elderly

Prevalencia y tratamiento de la patología oncológica en el anciano: El reto que se avecina

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