Cancer Pain: Part 2: Physical, Interventional and Complimentary Therapies; Management in the Community; Acute, Treatment-Related and Complex Cancer Pain: A Perspective from the British Pain Society Endorsed by the UK Association of Palliative Medicine and the Royal College of General Practitioners: Table 1

Raphael, Jacob; Hester, Joan; Ahmedzai, Sam H; Barrie, Janette; Farqhuar-Smith, Paul; Williams, John E.; Urch, Catherine; Bennett, Mike; Robb, Karen; Simpson, Brian; Pittler, Max H; Wider, Barbara; Ewer-Smith, Charlie; DeCourcy, James; Young, Ann; Liossi, Christina; McCullough, Renee; Rajapakse, Dilini; Johnson, Martin; Duarte, Rui; Sparkes, Elizabeth

doi:10.1111/j.1526-4637.2010.00841.x

Cited by 86 publications

(53 citation statements)

References 149 publications

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“…One third needed help by caregivers. Patients’ perception of QOL and caregivers’ perception may disagree because proxies tend to report more dysfunction in multiple aspects of QOL than stroke patients themselves [22]. Therefore, the QOL in our patients might be better than assessed.…”

Section: Discussionmentioning

confidence: 99%

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Quality of Life in Stroke Survivors after Local Intra-Arterial Thrombolysis

et al. 2008

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Background: We aimed to assess quality of life (QOL) and its predictors in stroke survivors after local intra-arterial thrombolysis (IAT) as well as to measure QOL according to the site of pretreatment vessel occlusion. Methods: From January 2000 to April 2004, 175 consecutive patients underwent IAT for acute ischemic stroke. Clinical and radiological data were collected prospectively. We contacted 135 stroke survivors after a mean of 923 (±431) days, 132 responded. QOL, assessed with EuroQol (EQ-5D), and functional abilities, measured with the modified Rankin Scale (mRS) and the Barthel Index, were compared, and predictors of QOL were analyzed. Results: Measured with EQ-5D, 56% of the patients reported a good QOL (EQ-5D Index ≥70). Low mRS and high Barthel Index scores at follow-up were associated with better overall QOL (Kendall’s tau >0.5). Nevertheless, 25% of the functionally independent patients (mRS 0–2) indicated a markedly impaired QOL (EQ-5D Index <70) and 10% of disabled patients indicated good QOL. QOL was significantly lower in patients with occlusion of the internal carotid artery compared to patients with occlusion of the basilar artery or the M1, M2 or M3/4 segment of the middle cerebral artery (EQ-5D Index: p = 0.005). A high National Institute of Health Stroke Scale score on admission and occlusion of the internal carotid artery were independent predictors of impaired QOL (p < 0.05). Conclusion: More than half of the stroke survivors treated with IAT reported a good QOL, mostly survivors with mild disabilities. QOL assessment gives information that is not provided by traditional outcome scores. Our results support guidelines to measure QOL in stroke research.

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Section: Discussionmentioning

confidence: 99%

“…An EQ-5D Index score ≥70 and an EQ VAS score ≥70 were considered to indicate good QOL, <70 as an impaired QOL. The validity of EuroQol for stroke patients and proxies and for postal follow-up has been shown previously [21, 22]. EuroQol has also been used in randomized controlled trials to assess the impact of a new drug on QOL [23].…”

Section: Methodsmentioning

confidence: 99%

Quality of Life in Stroke Survivors after Local Intra-Arterial Thrombolysis

et al. 2008

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“…‘Potential strategies’ to improve pain control were suggested through improving education for health care professionals as well as pain assessments. According to the British pain society ‘a more comprehensive model of managing cancer pain is needed’ that is ‘tailored to the needs of an individual’ [26]. The treatment of psychological problems was similarly deficient.…”

Section: Discussionmentioning

confidence: 99%

Quality of Life and Symptom Evaluation in Daily Oncology Practice: A Survey of 150 Patients with Advanced Gastrointestinal Tumours Receiving Palliative Chemotherapy

Schultheis¹,

Hofheinz²,

Gencer³

et al. 2013

Oncol Res Treat

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Background: Quality of life (QoL) is frequently investigated as a secondary endpoint in clinical trials but is rarely evaluated in clinical practice. The present survey sought to assess the QoL of patients with advanced gastrointestinal tumours receiving palliative chemotherapy. Furthermore, we wanted to compare the results of subscales of the generic EORTC QLQ-C30 (European Organization for Research and Treatment of Cancer, Quality of Life Questionnaire, version 3.0) using assessment tools with an emphasis on pain and depression. Patients and Methods: 150 patients with gastrointestinal tumours undergoing palliative chemotherapy completed 3 questionnaires. QoL was assessed using the EORTC QLQ-C30, Beck depression inventory (BDI) was utilised to measure the severity of patients’ depression and a visual analogue scale (VAS) was applied to measure patient’s pain intensity. Correlations between these assessments were calculated. Results: The survey revealed that treatment of pain and depression appeared to be inadequate in the present cohort of patients with metastatic gastrointestinal cancer. Good correlations between EORTC QLQ-C30 subscales and the VAS (r = 0.86), as well as the BDI (r = 0.63) were found. Conclusion: The present analysis indicates the need for better symptom control regarding the examples ‘pain’ and ‘depression’. In view of the good correlation between the EORTC QLQ-C30 and the BDI and VAS, further studies on the implementation of the EORTC QLQ-C30 as a screening tool, or for follow-up measurements in daily practice are warranted.

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“…In this regard, a rational treatment strategy should incorporate analgesic and causal measures. With this in mind, anti-neoplastic agents and radiotherapy, orthopedic devices and skeletal-stabilizing surgical procedures, physiotherapy and antibiotics to treat underlying infections should be applied whenever possible and as required to control pain [64,65] alongside analgesic and adjuvant agents [19,66,67].…”

Section: Pain Management In Malignant Hematologymentioning

confidence: 99%

Pain in malignant hematology

Niscola

Tendas

Scaramucci

et al. 2011

Expert Review of Hematology

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Pain is frequently experienced by patients with hematological malignancies, although it often receives little attention. Different underlying causes and mechanisms may sustain several pain syndromes in hematological malignant patients. Pain may be due to disease itself, to disease-related complications, to iatrogenic causes or may be associated with unrelated medical conditions. The management of pain in this setting requires a multidisciplinary approach, integrating analgesics and causal interventions. An accurate diagnostic assessment and the identification of the underlying causes and pathogenetic mechanisms may dictate the treatment approach. For most pain patients, the WHO's three-step analgesic scale for cancer pain relief can provide adequate relief with oral options, although difficult-to-treat pain syndromes, requiring a more complex treatment approach, may also be observed.

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Cited by 86 publications

References 149 publications

Quality of Life in Stroke Survivors after Local Intra-Arterial Thrombolysis

Quality of Life in Stroke Survivors after Local Intra-Arterial Thrombolysis

Quality of Life and Symptom Evaluation in Daily Oncology Practice: A Survey of 150 Patients with Advanced Gastrointestinal Tumours Receiving Palliative Chemotherapy

Pain in malignant hematology

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