Cancer of the tongue: Selecting appropriate therapy

McQuarrie, Donald G.

doi:10.1016/0011-3840(86)90022-5

Cited by 5 publications

(1 citation statement)

References 239 publications

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“…The tongue tumour may be treated in several different ways depending on the centre where the patient is initially seen. The reason for this multiplicity of treatment programmes is that no one approach has proved its superiority and there are no good randomized controlled trials to help the doctor in his treatment of choice (McQuarrie, 1986). Nowadays a team approach is used in the treatment of head and neck tumours in combined ocology clinics where patients are assessed by several different specialities who decide on optimal management.…”

Section: Discussionmentioning

confidence: 99%

The role of the carbon dioxide laser in treatment of carcinoma of the tongue

Williams¹,

Carruth²

1988

J. Laryngol. Otol.

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This paper presents 35 patients with carcinoma of the tongue who have been treated in Southampton using the Carbon Dioxide laser. The treatment programme for each individual patient was determined by radiotherapists and surgeons in a combined head and neck/oncology clinic. T1 carcinomas were treated by primary laser excision biopsy whereas larger tumours were treated first by conventional radiotherapy unless there was a significant contraindication to this treatment modality. Of 10 patients with T1 lesions nine are alive and well and disease free, but one patient died of other causes with no sign of recurrence. The minimum follow-up period has been two years. Of 25 patients with T2 and T3 lesions treated either before or after radiotherapy, nine are alive and disease-free, eleven died of disease and five patients died of other causes with no evidence of recurrence.

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Section: Discussionmentioning

confidence: 99%

The role of the carbon dioxide laser in treatment of carcinoma of the tongue

Williams¹,

Carruth²

1988

J. Laryngol. Otol.

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Interstitial brachytherapy and early tongue squamous cell carcinoma management

et al. 1990

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The results of treatment of 341 previously untreated patients with early squamous cell carcinoma (SCC) of the anterior two thirds of the tongue using iridium 192 implants (January 1974-December 1983) are presented. Furthermore, 265 patients underwent neck dissection, followed, in 102 cases, by radiotherapy. Incidence of local treatment complications was 19% (66 patients; however, only 3% (11 patients) needed more than a single medical treatment. Two months after completion of overall treatment, 326 patients (96%) were free of disease. Local failures occurred in 18% of cases; however, after successful salvage surgery this rate was reduced to 11%. Neck failures occurred in 18% of cases, but after successful salvage were reduced to 12%. Distant metastases were rare (1.5%), whereas metachronous cancers were frequent (102 patients). Survival rates were 61% (56% to 66%) at 3 years, 46% (41% to 51%) at 5 years, and 26% (23% to 34%) at 10 years. Deaths due to tongue cancer evolution (20%) equalled those due to metachronous cancers (18.5%) and intercurrent diseases (21%).

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Oral Cavity

Ingersoll

Goffinet

1989

Radiation Therapy of Head and Neck Cancer

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Cancer of the tongue: Selecting appropriate therapy

Cited by 5 publications

References 239 publications

The role of the carbon dioxide laser in treatment of carcinoma of the tongue

The role of the carbon dioxide laser in treatment of carcinoma of the tongue

Interstitial brachytherapy and early tongue squamous cell carcinoma management

Oral Cavity

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