Cancer of the External Auditory Canal

Nyrop, Mette; Grøntved, Ågot Møller

doi:10.1001/archotol.128.7.834

Cited by 119 publications

(103 citation statements)

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“…Clearly, surgery combined with or without radiotherapy is widely accepted as the standard of treatment and previous reports found that radiotherapy alone or salvage surgery after radiotherapy had depressingly poor prognoses. [1,4,5] However, the results of these previous studies are limited by the small number of patients involved and too long periods of time required to collect these cases. Long periods of surveillance resulted in different qualities in imaging studies used for staging and different surgical techniques.…”

Section: Discussionmentioning

confidence: 99%

“…Many publications have tried to evaluate survival in this aggressive disease, but patient numbers are limited (ranging from 10 to 39 patients, with most <30 patients), and surveillance periods are too long (ranging from 10 to 37 years, with most >15 years), possibly due to the rarity of this disease. [1][2][3][4][5][6][7][8][9] The quality of imaging studies (Computed tomography (CT) and magnetic resonance imaging (MRI)) has improved dramatically over time, and the accuracy of diagnosis of this disease is influenced by the quality of imaging. Similar reports contain many patients, but they are multi-institutional retrospective studies, with the surgical procedure and the surgeon different at each institution and surveillance periods are too long (>20 years).…”

Section: Introductionmentioning

confidence: 99%

“…Although many previous reports conclude that long-term prognosis of temporal bone SCC depends mainly on staging and primary treatment [1,4,5], there is no universally accepted staging system for temporal bone SCC. Due to the limited database for this tumor type, it has been difficult to determine any correlation between the clinical conditions, clinical symptoms and the extent of the lesion, and prognosis.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Prognostic factors for squamous cell carcinoma of the temporal bone: extensive bone involvement or extensive soft tissue involvement?

Ito

Hatano

Yoshizaki

2009

Acta Oto-Laryngologica

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Conclusion:Extensive bone erosion correlated with a worse prognosis of the squamous cell carcinoma (SCC) of the temporal bone but extensive soft tissue involvement did not correlate with prognosis in this study. Resectability of the tumor seems to be major prognostic factors of temporal bone SCC.Objective: Prognostic factors for SCC of the temporal bone were evaluated regarding initial clinical symptoms and radiographic imaging. Methods:Clinical symptoms of the patients with primary SCC of the external auditory canal (EAC) or middle ear (ME) were reviewed based on medical records. Correlation of clinical symptoms and cancer severity staging using the modified Pittsburgh classification was analyzed, along with disease-specific survival (DSS). Results:Sixteen patients with primary SCC of the EAC (n=13) or ME (n=3) were included in the study population. Disease-specific survival was not influenced by whether a hearing disturbance or otalgia was noted at the first medical examination.Extended bone involvement identified with imaging studies significantly correlated with worse prognosis (p<0.05). Prognoses of patients without extensive bone erosion were well and extensive (≥0.5 cm) soft tissue involvement did not correlate with prognosis in this study. Prognoses of patients with insufficient bone resection or no surgery were significantly poor (p<0.01).

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Prognostic factors for squamous cell carcinoma of the temporal bone: extensive bone involvement or extensive soft tissue involvement?

Ito

Hatano

Yoshizaki

2009

Acta Oto-Laryngologica

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“…The prognosis for patients suffering from an auditory canal carcinoma is rather poor as described in the literature [14,15]. The total survival time (T1, T2 and T4) of our patients was 28.2 ± 6.4 (CI: 15.6-40.9) months.…”

Section: Discussionmentioning

confidence: 46%

Cancer of the external auditory canal-diagnostic and treatment

Fleiner

Jumah

Göktas

2009

Indian J Otolaryngol Head Neck Surg

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“…All patients in the reconstruction of the EAC with STSG group showed preserved conformation of the new EAC for more than 12 months after surgery ( b ). apy alone or salvage surgery after radiotherapy [Kunst et al, 2008;Moody et al, 2000;Nyrop and Grøntved, 2002]. Sleeve resection, local canal resection (LCR) and LTBR are the most frequently applied surgical procedures in the management of patients with early-stage EAC carcinoma [Kunst et al, 2008;Yin et al, 2006;Zhang et al, 2013].…”

Section: Discussionmentioning

confidence: 99%

Hearing Preservation after Lateral Temporal Bone Resection for Early-Stage External Auditory Canal Carcinoma

Morita

Nakamaru²,

Homma³

et al. 2014

Audiol Neurotol

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Objective: To evaluate postoperative hearing outcomes after lateral temporal bone resection (LTBR) with reconstruction of the external auditory canal (EAC) and conductive function for early-stage EAC carcinoma. Methods: We retrospectively examined patients diagnosed with early-stage EAC carcinoma treated with surgery alone between January 2006 and December 2012. Patients who had postoperative adjuvant chemotherapy and/or radiotherapy were excluded. Patients receiving LTBR in combination with tympanoplasty were divided into two groups based on the reconstruction of the EAC with and without (w/o) split-thickness skin grafts (STSGs). Audiological data included the preoperative hearing thresholds and the most recent postoperative hearing thresholds obtained at least 12 months after surgery. The hearing outcome was evaluated based on pure-tone audiograms using the Committee on Hearing and Equilibrium guidelines of the American Academy of Otolaryngology-Head and Neck Surgery for the evaluation of the results of treatment of conductive hearing loss. The postoperative quality of life (QOL) for patients was evaluated using the Glasgow Benefit Inventory (GBI). Results: All patients (n = 15) achieved disease-free survival without significant morbidity or mortality. When we compared the mean air-bone gaps after surgery, those in the STSG group (n = 8) were found to be significantly lower than those in the w/o STSG group (n = 7; p < 0.001). The success rate for postoperative hearing was 75.0% in the STSG group, which was significantly higher than that in the w/o STSG group (p = 0.014). All patients in the w/o STSG group showed stenosis and closure of the EAC at fewer than 10 months after surgery. In contrast, all patients in the STSG group showed preserved conformation of the new EAC for more than 12 months after surgery. When we compared the mean GBI score between the two groups of patients, the overall and general health scores in the STSG group were found to be significantly higher than those in the w/o STSG group (p = 0.021, p = 0.001). Conclusions: Reconstruction of the EAC using a rolled-up STSG technique in combination with tympanoplasty after LTBR is useful for hearing preservation and the observation of locoregional lesions after surgery, resulting in improved QOL for patients. i 2014 S. Karger AG, Basel

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Cancer of the External Auditory Canal

Cited by 119 publications

References 10 publications

Prognostic factors for squamous cell carcinoma of the temporal bone: extensive bone involvement or extensive soft tissue involvement?

Prognostic factors for squamous cell carcinoma of the temporal bone: extensive bone involvement or extensive soft tissue involvement?

Cancer of the external auditory canal-diagnostic and treatment

Hearing Preservation after Lateral Temporal Bone Resection for Early-Stage External Auditory Canal Carcinoma

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