Cancer mortality predictions for 2021 in Latin America

Carioli, Greta; Vecchia, Carlo La; Bertuccio, Paola; Rodrı́guez, Teresa; Levi, Fabio; Boffetta, Paolo; Negri, Eva; Malvezzi, Matteo

doi:10.1097/cej.0000000000000702

Cited by 7 publications

(7 citation statements)

References 54 publications

(95 reference statements)

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“…In Russian, Ukrainian, Japanese, and Korean, men colorectal cancer mortality rates have surpassed those of stomach cancer only recently, and in Israeli, Hong Kong, and Australian women colorectal cancer ranks third after lung and breast cancer. The predicted mortality rates for this cancer in Russia, Ukraine, Hong Kong, and Japan are higher than or comparable with those in the EU (Dalmartello et al , 2022), whereas those in Israel, Korea, and Australia are lower and closer to the USA (Araghi et al , 2019), but not as low as seen in some countries of Latin America (Carioli et al , 2022). Trends for colorectal cancer in the studied countries showed favorable trends, both registered and projected.…”

Section: Discussionmentioning

confidence: 76%

Cancer mortality and predictions for 2022 in selected Australasian countries, Russia, and Ukraine with a focus on colorectal cancer

Pizzato

Vecchia

Malvezzi

et al. 2022

European Journal of Cancer Prevention

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Objective We aimed at predicting cancer mortality rates for the current year for the Russian Federation, Ukraine, Israel, Hong Kong SAR, Japan, Korea, and Australia, with a focus on colorectal cancer. Methods We retrieved official death certification and population data from the WHO and the United Nations Population Division databases. We analyzed mortality for all cancers combined and for 10 major cancer sites from 1970 to 2019, or the latest available year. We predicted numbers of deaths and age-standardized mortality rates for 2022 using Poisson joinpoint regression models. We estimated the number of averted deaths over the period 1994–2022 because of the decline in mortality rates. Results Total cancer mortality declined in all countries and both sexes. Russia had the highest total cancer predicted rates for 2022: 156.4/100 000 (world standard) in men and 81.4 in women; the lowest rates were reported in Israeli men (90.6/100 000) and Korean women (44.5/100 000). Between 1994 and 2022, a total of 1 487 000 deaths were estimated to be avoided in Russia, 502 000 in Ukraine, 58 000 in Israel, 102 000 in Hong Kong SAR, 1 020 000 in Japan, 533 000 in the Republic of Korea, and 263 000 in Australia. Colorectal cancer mortality trends were downward for the last decades with favorable predictions for 2022 in both sexes. Conclusion In the countries considered, predicted downward trends started later and were less marked than those in the European Union and the USA. Despite overall favorable predictions, colorectal cancer remains one of the major causes of cancer mortality.

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Section: Discussionmentioning

confidence: 76%

Cancer mortality and predictions for 2022 in selected Australasian countries, Russia, and Ukraine with a focus on colorectal cancer

Pizzato

Vecchia

Malvezzi

et al. 2022

European Journal of Cancer Prevention

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“…Among female malignancies, breast cancer ranks first and has become one of the major public health problems in the world (89,90). With the increasing improvement of breast cancer treatment methods, in addition to traditional surgery, adjuvant chemoradiotherapy and hormone therapy, targeted gene therapy and immunotherapy have also been used in clinical practice.…”

Section: Nlr Inflammasomes and Breast Cancermentioning

confidence: 99%

Mechanism of inflammasomes in cancer and targeted therapies

Zou

Zhou

et al. 2023

Front. Oncol.

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Inflammasomes, composed of the nucleotide-binding oligomerization domain(NOD)-like receptors (NLRs), are immune-functional protein multimers that are closely linked to the host defense mechanism. When NLRs sense pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs), they assemble into inflammasomes. Inflammasomes can activate various inflammatory signaling pathways, including nuclear factor kappa B (NF-κB) and mitogen-activated protein kinase (MAPK) signaling pathways, and produce a large number of proinflammatory cytokines, which are closely associated with multiple cancers. They can also accelerate the occurrence and development of cancer by providing suitable tumor microenvironments, promoting tumor cell proliferation, and inhibiting tumor cell apoptosis. Therefore, the exploitation of novel targeted drugs against various inflammasomes and proinflammatory cytokines is a new idea for the treatment of cancer. In recent years, more than 50 natural extracts and synthetic small molecule targeted drugs have been reported to be in the research stage or have been applied to the clinic. Herein, we will overview the mechanisms of inflammasomes in common cancers and discuss the therapeutic prospects of natural extracts and synthetic targeted agents.

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“…The age of its onset is mainly 40 years and above of age, and the incidence rate increases with respect to age [28,29]. The mortality rate is second only to lungs cancer [30]. Prostate cancer has become one of the most common cancers among men in the world especially in Europe and the United States [21,22] with the incidence rate occurring more in African American men than any other racial group [31].…”

Section: Figure 1 Sectional View Of Prostate Glandmentioning

confidence: 99%

An Online Doctor's and Patient help Desk Assistant for Early Diagnoses of Prostate Cancer in the Rural Areas of Bayelsa State

Omote

Fawei

Dienagha³

2022

IJSRCSEIT

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The shortage and unavailability of medical practitioners particularly medical doctors in the world has created deficiency in the health sector, which is even more prevalent in the developing countries. This has made rural dwellers in developing countries to experience chronic diseases like prostate cancer, lung cancer, breast cancer and so on which leads to mortality and disabilities. Prostate cancer is a male disease that occurs in the malignant tumors of the prostate epithelium. In this paper, we present an online doctor’s and patient help desk assistant for the diagnoses of prostate cancer at its early stage in the rural areas where there are no health professionals. The system offers medical assistance to patients by providing diagnostic information of their status based on a set of questions answered with respect to prostate cancer. The system is developed with Java Expert System Shell (JESS) alongside other web programming tools. The result from the system evaluation with 50 participants show greater than 95 percent accuracy on expert confirmation.

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Cancer mortality predictions for 2021 in Latin America

Cited by 7 publications

References 54 publications

Cancer mortality and predictions for 2022 in selected Australasian countries, Russia, and Ukraine with a focus on colorectal cancer

Cancer mortality and predictions for 2022 in selected Australasian countries, Russia, and Ukraine with a focus on colorectal cancer

Mechanism of inflammasomes in cancer and targeted therapies

An Online Doctor's and Patient help Desk Assistant for Early Diagnoses of Prostate Cancer in the Rural Areas of Bayelsa State

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