Cancer Incidence Among Adults With HIV in a Population-Based Cohort in Korea

Park, Boyoung; Ahn, Kyoung Hwan; Choi, Yunsu; Kim, Jung Ho; Seong, Hye; Kim, Youn Jeong; Choi, Jun Young; Song, Joon Young; Lee, Eunjung; Jun, Yoon Hee; Yoon, Young Kyung; Choi, Won Suk; Lee, Myungsun; Seong, Jaehyun; Kim, Shin‐Woo

doi:10.1001/jamanetworkopen.2022.24897

Cited by 16 publications

(13 citation statements)

References 38 publications

(107 reference statements)

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“…HIV can lead to acquired immune deficiency syndrome (AIDS) and susceptibility to opportunistic infections and certain malignant tumors [ 60 ]. Chronic diseases, including cancer, have emerged as health problems in HIV-infected people in middle-income and high-income countries [ 61 ]. HIV-induced immune deficiency was the most common risk factor for developing malignancies [ 62 ].…”

Section: Hiv and Tcmentioning

confidence: 99%

The Potential Role of Virus Infection in the Progression of Thyroid Cancer

Wu,

Jiang,

et al. 2024

World J Oncol

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Multiple factors have engaged in the progression of thyroid cancer (TC). Recent studies have shown that viral infection can be a critical factor in the pathogenesis of TC. Viruses, such as Epstein-Barr virus (EBV), hepatitis C virus (HCV), human immunodeficiency virus (HIV), and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), may play an essential role in the occurrence, development, and even prognosis in TC. This review mainly explored the potential role of viral infection in the progress of TC. The possible mechanisms could be recognizing the host cell, binding to the receptors, affecting oncogenes levels, releasing viral products to shape a beneficial environment, interacting with immune cells to induce immune evasion, and altering the pituitary-thyroid axis. Thus, comprehensive knowledge may provide insights into finding molecular targets for diagnosing and treating virus-related TC.

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Section: Hiv and Tcmentioning

confidence: 99%

The Potential Role of Virus Infection in the Progression of Thyroid Cancer

Wu,

Jiang,

et al. 2024

World J Oncol

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“…Recent estimates also suggest its incidence has now surpassed Kaposi sarcoma and non-Hodgkin lymphoma [108 && ]. PLWH are approximately 1.5-3 times more likely to develop lung cancer compared to HIV-uninfected individuals [94,103,105,107,[109][110][111][112][113][114][115][116][117][118][119]. Fortunately, though, over the last two decades, incidence rates of lung cancer have significantly declined and the standardized incidence ratios with the general population have also started to normalize [ Nonetheless, the prognosis of PLWH diagnosed with lung cancer remains especially grim, particularly when compared to HIV-uninfected patients.…”

Section: Human Immunodeficiency Virus and Lung Cancermentioning

confidence: 99%

HIV and chronic lung disease

Leung

2022

Current Opinion in HIV and AIDS

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Purpose of reviewAs people living with human immunodeficiency virus (HIV, PLWH) age, aging-related comorbidities have come into focus as major challenges to their overall health. In this review, an in-depth overview of the two most commonly encountered chronic lung diseases in PLWH, chronic obstructive pulmonary disease (COPD) and lung cancer, is provided. Recent findingsThe risk for both COPD and lung cancer remains significantly higher in PLWH compared to the HIVuninfected population, although fortunately rates of lung cancer appear to be declining over the last two decades. Outcomes for PLWH with these conditions, though, continue to be poor with worse survival rates in comparison to the general population. PLWH still face major barriers in accessing care for these conditions, including a higher likelihood of being underdiagnosed with COPD and a lower likelihood of being referred for lung cancer screening or treatment. A lack of evidence for optimal treatment strategies for both COPD and lung cancer still hampers the care of PLWH with these conditions. SummaryCOPD and lung cancer represent substantial burdens of disease in PLWH. Improved access to standard-ofcare screening and treatment and greater investigation into therapeutic responses specifically in this population are recommended.

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“…Several theoretical frameworks have been proposed to explain this potential link, including immune surveillance impairment, chronic inflammation, and the role of oncogenic viruses, which are more prevalent in individuals with HIV [ 7 ]. However, studies exploring the incidence of BC in HIV-infected populations have yielded mixed results, underscoring the need for a comprehensive review of the literature to understand the nuances of this relationship [ 8 ].…”

Section: Introductionmentioning

confidence: 99%

Navigating the Nexus: HIV and Breast Cancer—A Critical Review

Marino,

Pavone,

Martorana

et al. 2024

IJMS

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Despite significant advances in the management of antiretroviral therapy (ART), leading to improved life expectancy for people living with HIV (PLWH), the incidence of non-AIDS-defining cancers, including breast cancer, has emerged as a critical concern. This review synthesizes current evidence on the epidemiology of breast cancer among HIV-infected individuals, highlighting the potential for an altered risk profile, earlier onset, and more advanced disease at diagnosis. It delves into the molecular considerations underpinning the relationship between HIV and breast cancer, including the role of immunosuppression, chronic inflammation, and gene expression alterations. Additionally, it examines the complexities of managing breast cancer in the context of HIV, particularly the challenges posed by ART and anticancer agents’ cross-toxicities and drug–drug interactions. The review also addresses survival disparities, underscoring the need for improved cancer care in this population. By identifying gaps in knowledge and areas requiring further research, this review aims to illuminate the complexities of HIV-associated breast cancer, fostering a deeper understanding of its epidemiology, molecular basis, and clinical management challenges, thereby contributing to better outcomes for individuals at the intersection of these two conditions. This narrative review systematically explores the intersection of HIV infection and breast cancer, focusing on the impact of HIV on breast cancer risk, outcomes, and treatment challenges.

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Cancer Incidence Among Adults With HIV in a Population-Based Cohort in Korea

Cited by 16 publications

References 38 publications

The Potential Role of Virus Infection in the Progression of Thyroid Cancer

The Potential Role of Virus Infection in the Progression of Thyroid Cancer

HIV and chronic lung disease

Navigating the Nexus: HIV and Breast Cancer—A Critical Review

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