2018
DOI: 10.1186/s40169-018-0193-6
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Cancer; an induced disease of twentieth century! Induction of tolerance, increased entropy and ‘Dark Energy’: loss of biorhythms (Anabolism v. Catabolism)

Abstract: Maintenance of health involves a synchronized network of catabolic and anabolic signals among organs/tissues/cells that requires differential bioenergetics from mitochondria and glycolysis (biological laws or biorhythms). We defined biological circadian rhythms as Yin (tumoricidal) and Yang (tumorigenic) arms of acute inflammation (effective immunity) involving immune and non-immune systems. Role of pathogens in altering immunity and inducing diseases and cancer has been documented for over a century. However,… Show more

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Cited by 17 publications
(109 citation statements)
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References 259 publications
(571 reference statements)
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“…1,5 We also presented evidence that, unlike popularized notions that cancer is 100, 200, or 1000 diseases, cancer is only one disease; the severely disrupted loss of highly regulated biorhythms of effective immunity, provided through tumoricidal (Yin) and tumorigenic (Yang) arms (autonomic sympathetic and parasympathetic) of acute inflammation. 5 In this multidisciplinary perspective, we further provide evidence that nearly all clinically and pathologically established disease categories (neonatal, hereditary, congenital, and induced) that occasionally occurred at the rates of 1-5% in the past century, have been shifted to increase the population of induced diseases in young and old. To achieve maximum disease status, particularly in America medical establishment employed combined methods of (a) heavy advertisements for the consumption of numerous drugs; (b) frequent vaccination of young and old with pathogenspecific vaccines; and (c) cumulative exposures of public to environmental hazards.…”
Section: From Rockefeller Medicine To Gates Vaccines: Reductionist Anmentioning
confidence: 96%
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“…1,5 We also presented evidence that, unlike popularized notions that cancer is 100, 200, or 1000 diseases, cancer is only one disease; the severely disrupted loss of highly regulated biorhythms of effective immunity, provided through tumoricidal (Yin) and tumorigenic (Yang) arms (autonomic sympathetic and parasympathetic) of acute inflammation. 5 In this multidisciplinary perspective, we further provide evidence that nearly all clinically and pathologically established disease categories (neonatal, hereditary, congenital, and induced) that occasionally occurred at the rates of 1-5% in the past century, have been shifted to increase the population of induced diseases in young and old. To achieve maximum disease status, particularly in America medical establishment employed combined methods of (a) heavy advertisements for the consumption of numerous drugs; (b) frequent vaccination of young and old with pathogenspecific vaccines; and (c) cumulative exposures of public to environmental hazards.…”
Section: From Rockefeller Medicine To Gates Vaccines: Reductionist Anmentioning
confidence: 96%
“…It should be noted that prior to vaccination of public with viruscontaminated polio vaccines, decision makers minimized, downplayed, ignored, and harassed a highly competent and concerned microbiologist (Bernice Eddy) at NIH who discovered that the polio vaccines had live and filterable viruses (eg, Simian virus, SV-40) and predicted that contaminated polio vaccines could cause cancer epidemic. 1,5,8,17 The loss of too many lives and numerous polio vaccine injuries resulted in lawsuits against NIH and DHHS and resignation of directors of NIH and DHHS, constituting little more than a slap on the hand!. 1 Despite this record, the power of the medical establishment over exclusive decision-making and over public health in general increased to its current scary level.…”
Section: Initiators Of Cancer (Tumor) Growth and Theory Of Immune Surmentioning
confidence: 99%
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“…When the child is born and with contact to the oxygen in the atmosphere, many challenges of the environment and its adaptation to it, the developmental program adjustments, and the terminal differentiation of these developmental programs; shaping of the lymphoid system, maturation of the cells of the immune system and their thymus and bone marrow settlement are necessary for mitochondrial efficiency and strong immunity. Therefore, there is a need for bioenergetic health and strongly working cell-mediated and humoral immunity to give protection to external threads after birth and throughout life (187,188).…”
Section: Therapeutic Implications Of the Metabolic Flexibility Of Thementioning
confidence: 99%
“…A fine tuning in the cell, where flavonoids may exert an apparently contradictory action, does exist. Moreover, the hypothesis that cancer might be closely associated with an imbalance in the energy homeostass, therefore including also ROS signaling and mitochondria oscillation, has been recently addressed [ 17 , 97 ].…”
Section: Insights On the Role Of Flavonoids In Cancermentioning
confidence: 99%