Canalicular adenoma immunoprofile: a case report

Abstract

The histological diagnosis of benign salivary tumors such as CA can be confirmed by immunohistochemistry.

Canalicular adenoma of the upper lip: a short case study

“…Differential diagnosis is made with a mucoid cyst, vascular tumor, phleboliths, lipoma, or another salivary gland tumor, including basal cell adenoma, low-grade adenocarcinoma, and cystic adenoid carcinoma. The distinction between these salivary gland tumors and multifocal CA can be difficult, the immunohistochemistry is useful for the diagnosis [4,5]. The treatment is always surgical in nature.…”

Clinical, morphological and immunohistochemical findings in canalicular adenoma

“…The peak incidence of CAd is in the seventh decade of life and the tumor is uncommon in patients younger than 50 years. There are no reports of CAd in pediatric patients 1,3,5 . The age of the patients shown in Table 2 ranged from 26 to 85 years, with a mean age of 68 years.…”

“…This tumor is believed to arise from duct reserve cells, especially those of the minor salivary glands, and commonly affects the upper lip. Canalicular adenoma accounts for 1-3% of all salivary gland tumors and is more common in female patients older than 50 years [1][2][3] .…”

“…Conservative surgical excision is the most indicated treatment. Recurrences are rare, but multifocal tumors have a strong tendency to recur [1][2][3] . The objective of this study was to describe the clinical, morphological and immunohistochemical findings of two cases of CAd in the minor salivary glands and to compare the findings with case reports published in the literature over the last 10 years.…”

Adenoma canalicular multifocal del labio superior: reporte de un caso y revisión de la literatura

“…En la histopatología, se observan cordones de doble fila de células columnares o cúbicas con patrón alternante descrito como "collar de perlas" (beading): los cordones se disponen paralelamente en contacto estrecho y posteriormente se separan formando estructuras similares a ductos que dan origen al término "canalicular" de este tumor (1,3,4,(5)(6)(7)(8)(9)(11)(12)(13)(14). Estas estructuras similares a ductos, pueden dilatarse y llegar a conformar quistes con formaciones papilares (1,5,11).…”