Can vitamin D supplementation improve grip strength in elderly nursing home residents? A double-blinded controlled trial

Smedshaug, Guro Berge; Pedersen, Jan I.; Meyer, Haakon E

doi:10.1080/03461230701422528

Cited by 17 publications

(14 citation statements)

References 28 publications

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“…Targeting these subjects with an intervention aimed at preserving muscle strength and mobility thus appears sensible. However, in concordance with our findings, studies on vitamin D supplementation in hospitalised older subjects (57,58) or residents in nursing homes (3,7) showed mixed results for the effects of vitamin D supplementation on muscle strength and mobility. Thus, convincing evidence that vitamin D supplementation may be a useful measure is lacking (14,28,59) .…”

Section: Study Populationsupporting

confidence: 90%

“…] and preserving both muscle mass and strength. A number of dietary measures (supplementation with protein, energy, or n-3 polyunsaturated fatty acids, micronutrient supplementations) (3)(4)(5)(6)(7)(8) and exercise interventions (9,10) or their combinations have been tested (11)(12)(13)(14) . Among these interventions, supplementation with vitamin D has been promoted as having positive effects in older persons with respect to the risk of falls and fractures (15,16) .…”

Section: Introductionmentioning

confidence: 99%

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Vitamin D supplementation and its influence on muscle strength and mobility in community‐dwelling older persons: a systematic review and meta‐analysis

Rosendahl-Riise

Spielau

Ranhoff

et al. 2016

J Human Nutrition Diet

112

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BackgroundIt has been suggested that vitamin D status or supplementation is important for maintaining or improving muscle strength and mobility in older adults. The study results, however, do not provide consistent results. We therefore aimed to summarise the available evidence systematically, including only studies conducted in community‐dwelling older persons.MethodsA systematic search of the literature was performed in April of 2016. The systematic review includes studies that used vitamin D with or without calcium supplementation as the exposure variable and various measurements of muscle strength and mobility. The meta‐analysis was limited to studies using hand grip strength (HGS) and timed‐up‐and‐go test as the outcome variables.ResultsA total of 15 studies out of 2408 articles from the literature search were included in the systematic review, providing 2866 participants above the age of 65 years. In the majority of studies, no improvement in muscle strength and mobility was observed after administration of vitamin D with or without calcium supplements. In the meta‐analysis, we observed a nonsignificant change in HGS [+0.2 kg (95% confidence interval = −0.25 to 0.7 kg; seven studies)] and a small, significant increase in the timed‐up‐and‐go test [0.3 s (95% confidence interval = 0.1 to 0.5 s; five studies)] after vitamin D supplementation. The meta‐analyses showed a high degree of heterogeneity between the studies.ConclusionsIn conclusion, we observed no improvement in muscle strength after the administration of vitamin D with or without calcium supplements. We did find a small but significant deterioration of mobility. However, this is based on a limited number of studies and participants.

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Section: Study Populationsupporting

confidence: 90%

Section: Introductionmentioning

confidence: 99%

Vitamin D supplementation and its influence on muscle strength and mobility in community‐dwelling older persons: a systematic review and meta‐analysis

Rosendahl-Riise

Spielau

Ranhoff

et al. 2016

J Human Nutrition Diet

112

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“…We did not locate any articles regarding the effect of cheese, ice cream, yoghurt, buttermilk, kefir, cultured milk products, selenium, iodine, vitamin B2, vitamin B12, phosphorus, potassium, magnesium, vitamin K, Vitamin B3, or zinc. Eighteen trials provided vitamin D supplementation [39,42,43,[45][46][47][48][49][50][51][52][53][54][55][56][57][58][59] of which one provided the intervention group with an extremely low amount of vitamin D of 0.5 µg/day [46]. For this reason, the trial was excluded from all analyses.…”

Section: Resultsmentioning

confidence: 99%

Supplemental protein from dairy products increases body weight and vitamin D improves physical performance in older adults: a systematic review and meta-analysis

et al. 2018

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The purpose of these systematic review and meta-analysis was to assess the effectiveness of dairy components on nutritional status and physical fitness in older adults, as evidence for efficacy of the supplementation of these components is inconclusive. Scopus and MEDLINE were searched. Main inclusion criteria for articles were as follows: double-blind, randomized, placebo-controlled trials including participants aged ≥55 years who received dairy components or a placebo. Outcome measures were nutrient status (body weight and body mass index) and physical fitness (body composition, muscle strength, and physical performance). Thirty-six trials with 4947participants were included. Most trials investigated protein and vitamin D supplementation and showed no effect on the outcomes. Meta-analysis on the effect of protein on body weight showed a significant increase in mean difference of 1.13 kg (95% confidence interval, 0.59-1.67). This effect increased by selecting trials with study a duration of 6 months in which less nourished and physically fit participants were included. Trials where the participants were (pre-)frail, inactive older adults or when supplementing ≥20 g of protein per day tended to increase lean body mass. Only small significant effects of vitamin D supplementation on Timed Up and Go (mean difference -0.75 seconds; 95% confidence interval -1.44 to -0.07) were determined. This effect increased when vitamin D doses ranged between 400 and 1000 IU. Additional large randomized controlled trials of ≥6 months are needed regarding the effect of dairy components containing an adequate amount of vitamin D (400-1000 IU) and/or protein (≥20 g) on nutritional status and physical fitness in malnourished or frail older adults.

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“…Even though vitamin D supplementation resulted in increased grip strength and isokinetic strength in our study, it had no effect on chair stand test performance. However, McCarthy et al (21) stated that isokinetic knee extensor strength was an important but moderate predictor of chair stand test performance and additional independent variables such as leg power, leg endurance, posture, and psychological variables may have contributed to the variance in chair stand test performance.…”

Section: Discussionmentioning

confidence: 99%

Do the effects of vitamin D supplementation on muscle strength differ according to age

Sonuparlak¹

2018

tjgeri

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Introduction: Vitamin D plays an important role in musculoskeletal health and its use improves muscle strength. However, the effect of vitamin D use on muscle strength in women of different ages is yet to be investigated. Therefore, in this study, we aimed to evaluate the effect of vitamin D use on muscle strength in women of different age groups and determine the differences of muscle strength gain between age groups.Materials and Method: Sixty-three women with calcidiol levels<30 ng/mL were randomly assigned and stratified by their age group as follows: Group I (aged 40-49 years), Group II (aged 50-59 years) and Group III (aged 60-69 years). Calcidiol levels, body mass index, fat free mass, percent fat, grip strength, arm curl, chair stand and isokinetic concentric flexor and extensor peak torque and power at 60°•s−1 and 180°•s−1 were assessed at baseline and six months after oral cholecalciferol supplementation.Results: Vitamin D supplementation caused significant improvement in body mass index, arm curl, grip strength and knee flexor and extensor peak torque and power at 60°•s−1 and 180°•s−1 in all groups (p<0.05). Knee flexor power at 60°•s−1 and extensor power at 180°•s−1 were significantly higher in group I than in group III (p<0.025).Conclusion: Muscle strength in response to vitamin D supplementation increased in all age groups, and isokinetic muscle power was the highest in the youngest age group studied.Giriş: D vitamininin muskuloskeletal sağlık için önemli olduğu ve D vitamin kullanımının kas kuvvetini arttırdığı bilinmektedir. Ancak, farklı yaşlardaki kadınlarda, D vitamin kullanımının kas kuvvetine etki farklılığını araştıran çalışma yoktur. Bu nedenle bu çalışmada, farklı yaş gruplarındaki kadınlarda D vitamin kullanımının kas kuvvetine etkisini değerlendirmek ve yaş grupları arasındaki kuvvet değişim farkını belirlemek amaçlanmıştır.Gereç ve Yöntem: Kalsidiol düzeyi <30ng/ml olan altmış üç kadın rasgele olarak yaş gruplarına göre sınıflandırıldı ve tabakalandı: Grup I (40-49 yaş arasında), Grup II (50-59 yaş arasında), ve Group III (60-69 yaş arasında). Kalsidiol düzeyi, beden kütle indeksi, yağsız kütle, yüzde yağ, kavrama kuvveti, kol bükme, otur kalk testleri ile 600.s-1 and 1800.s-1 hızlarda izokinetik konsantrik fleksör ve ekstensör zirve tork ve güç başlangıçta ve oral kolekalsifereol verildikten altı ay sonra değerlendirildi.Bulgular: D vitamin kullanımı tüm yaş gruplarında beden kütle indeksi, kol bükme, kavrama kuvveti, 600.s-1 and 1800.s-1 hızlarda diz fleksör ve ekstensör zirve tork ve güçte artışa neden oldu (p<0.05). Grup I'de, Grup III'e kıyasla 600.s-1 hızda fleksör güç ve 1800.s-1 hızda ekstensör güç daha büyüktü (p<0.025).Sonuç: D vitamin kullanımı sonucu tüm yaş gruplarında kas kuvveti arttı ve izokinetik kas gücü artışının genç yaş grubunda daha fazla olduğu belirlendi.

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Can vitamin D supplementation improve grip strength in elderly nursing home residents? A double-blinded controlled trial

Cited by 17 publications

References 28 publications

Vitamin D supplementation and its influence on muscle strength and mobility in community‐dwelling older persons: a systematic review and meta‐analysis

Vitamin D supplementation and its influence on muscle strength and mobility in community‐dwelling older persons: a systematic review and meta‐analysis

Supplemental protein from dairy products increases body weight and vitamin D improves physical performance in older adults: a systematic review and meta-analysis

Do the effects of vitamin D supplementation on muscle strength differ according to age

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