volume 31, issue 3, P168-175 2016
DOI: 10.1590/s0102-865020160030000004
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Abstract: ABSTRACT PURPOSE:To investigate the effects of thiamine pyrophosphate (TPP) against desflurane induced hepatotoxicity. METHODS:Thirty experimental animals were divided into groups as healthy (HG), desflurane control (DCG) , TPP and desflurane group (TDG). 20 mg/kg TPP was injected to intraperitoneally TDG. After one hour of TPP administration, desflurane was applied for two hours. After 24 hours, liver tissues of the animals killed with decapitation were removed. The oxidant/antioxidant levels and ALT, AST an…

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