Can the inclusion of the dimethylaminohexadecyl methacrylate (DMAHDM) monomer in adhesive systems provide to them an antibacterial effect? A systematic review

Oliveira, Francisca Jennifer Duarte de; Costa, Moan Jéfter Fernandes; Sette‐de‐Souza, Pedro Henrique; Araújo, Diana Ferreira Gadelha de; Borges, Boniek Castillo Dutra

doi:10.1016/j.ijadhadh.2022.103291

Cited by 1 publication

(1 citation statement)

References 64 publications

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“…In recent years, DMADDM and DMAHDM have become the most commonly used quaternary ammonium mono-methacrylate monomers due to their facial synthesis and strong antibacterial activity, as reported in numerous studies [51,[67][68][69][70][71][72][73]. Wang et al evaluated the antibacterial activity of a bioactive dental composite containing 3% DMAHDM against S. mutans, S. sanguinis (Streptococcus sanguinis), and S. gordonii (Streptococcus gordonii) in a biofilm model.…”

Section: Mono-methacrylate Quaternary Ammonium Monomersmentioning

confidence: 99%

Recent Advances in Quaternary Ammonium Monomers for Dental Applications

Liang,

Yu,

et al. 2024

Materials

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Resin-based dental materials have been one of the ideal choices among various materials in the treatment of dental caries. However, resin-based dental materials still have some drawbacks, such as the lack of inherent antibacterial activity. Extensive research has been conducted on the use of novel quaternary ammonium monomers (QAMs) to impart antibacterial activity to dental materials. This review provides a comprehensive overview of the recent advances in quaternary ammonium monomers (QAMs) for dental applications. The current progress and limitations of QAMs are discussed based on the evolution of their structures. The functional diversification and enhancement of QAMs are presented. QAMs have the potential to provide long-term antibacterial activity in dental resin composites, thereby prolonging their service life. However, there is a need to balance antibacterial performance with other material properties and the potential impact on the oral microbiome and general health. Finally, the necessity for further scientific progress in the development of novel quaternary ammonium monomers and the optimization of dental resin formulations is emphasized.

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