Can misoprostol reduce blood loss in laparoscopy-assisted vaginal hysterectomy?

Abstract

These data do not support the use of rectal misoprostol to reduce blood loss during LAVH. The pharmacoclinical effects of misoprostol in the uterus should be clarified.

Rectal misoprostol for myomectomy: A randomised placebo‐controlled study

“…Other studies have assessed the effects of using misoprostol pre‐operatively to reduce intra‐operative bleeding during hysterectomy performed as a method of treatment for symptomatic leiomyomas. Park et al . compared 49 women who received 400 μg of rectal misoprostol 1 h before having laparoscopic‐assisted vaginal hysterectomy (LAVH) for leiomyoma with 68 women who did not.…”