“…One of the potential underlying mechanisms of ADEM in association with SARS-CoV-2 is the cytokine pathway activation, which is known to be involved in the pathology of ADEM. It has been stated to result from T cells affected by SARS-CoV-2 inducing a storm of cytokines, especially IL-6 [ [16] , [17] , [18] ]. This results in sequences of immune responses that may play an important role in the pathogenesis of ADEM [ 19 ].…”