Can Hepatitis A Vaccine Provide Protection Against COVID-19?

Sarıalıoğlu, Faık; Belen, Fatma Burcu; Haberal, Mehmet

doi:10.6002/ect.2020.0109

Cited by 17 publications

(15 citation statements)

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“…However, the less susceptible, and milder nature of COVID-19 infections in young children remains unclear. Several reports suggest that the heterologous immunity, induced by active immunization of children from birth to 5 years of age, could be the possible reason for the less susceptible and milder nature of COVID-19 infection [19,20,21]. Furthermore, we found that the ICU admission rate was higher in COVID-19 patients with underlying medical conditions, showing that although the clinical presentation of COVID-19 in pediatric patients may be milder, clinical course can be more severe [4,6,9].…”

Section: A C C E P T E D a R T I C L Ementioning

confidence: 51%

Comparison of clinical features and laboratory findings of coronavirus disease 2019 and influenza A and B infections in children: a single-center study

Siddiqui

Gultekingil²,

Bakırcı³

et al. 2021

Clin Exp Pediatr

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Section: A C C E P T E D a R T I C L Ementioning

confidence: 51%

Comparison of clinical features and laboratory findings of coronavirus disease 2019 and influenza A and B infections in children: a single-center study

Siddiqui

Gultekingil²,

Bakırcı³

et al. 2021

Clin Exp Pediatr

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“…The social distancing measure thus prevents infection. [11]. "Live vaccines have the very broad benefit of going much further than protecting just against the targeted disease" as per Medical Journal publications.…”

Section: C19-svt : Architecture and Componentsmentioning

confidence: 99%

COVID-19 Social Vaccine Toolkit(C19-SVT)

kumar¹

2020

Preprint

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COVID-19 Social Vaccine Toolkit(C19-SVT) addresses social and behavioral modalities which help beat the corona virus. The users become aware of various measures such as social distancing, use of masks, Sanitisation etc. The C19-SVT brings awareness of various prophylactic tasks to combat the COVID-19 Infection. Unlike a biological vaccine, the C19-SVT prevents the spread of COVID-19 infection through knowledge dissemination and training skill sets that are essential. A person who has better understanding of how the corona virus spreads, symptoms of the disease, social distancing measures, washing hands, Biological vaccination and other dos and don'ts will be better prepared to prevent this highly infectious disease. Good understanding of fundamentals of COVID-19 preventive measures is the necessity at this critical moment. The C19-SVT is informative, timely, interactive, state of the art tool for the masses. It is educative and knowledge dissemination tool with relevant content. The C19-SVT is continuously updated and reviewed by Medical experts. It is accessible for general public free of cost and has global acceptance. The number of users are growing and the usefulness of the C19-SVT is evident from the feedback received. The clinical trials are being initiated to study the effectiveness of C19-SVT. The robust, fault tolerant architecture of C19-SVT incorporating best practices and protocols with solid scientific basis is the way forward for multi-pronged approach in global fight against COVID-19 infection.

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“…Recently, limited ecological studies have sparked controversy among researchers about the protective impact of the non-specific effect of routinely used BCG vaccines against COVID-19 (4,5). A similar claim has been made about the protective impact of hepatitis A and influenza vaccines (12,13). However, several trials are running to investigate the potential influence of BCG vaccination and Anti-HAV presence on COVID-19 morbidity and mortality.…”

Section: Introductionmentioning

confidence: 99%

COVID-19 Disease and Interferon-γ: Has it a Protective Impact on Mortality?

Husseini¹

2020

Erciyes Med J

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The complex coincidence of several immunopathological, socio-cultural, and health infrastructure factors may affect the COVID-19 related mortality among different populations. The impact of the age on disease progression has been confirmed in several studies. Recently limited ecological and clinical studies have sparked controversy among researchers about the protective impact of the non-specific effect of routinely used Bacille Calmette-Guerin (BCG), Hepatitis A virus (HAV), and influenza (Flu) vaccines or their natural infections against COVID-19. In the present study, variables, including BCG vaccination coverage, HAV prevalence, and population age distributions, from 59 countries were analyzed to examine their potential association with COVID-19 infection and related mortality rate. Concerning COVID-19 cases/million population (1MP) and mortality, there are significant differences between countries with and without BCG vaccination programs (p-value <0.001). A significant negative correlation between both BCG coverage and HAV prevalence with COVID-19 related mortality was also found (r (59)=-0.4, p-value <0.05), (r (59) =-0.3, p-value <0.01). Based on the results of the present study, previous ecological analyses and available epidemiological evidence, along with knowledge of the immune response to BCG, HAV and influenza vaccination, as well as COVID-19 infection progression, the current study suggest a hypothesis that IFN-γ induced immune response which could be triggered by BCG, HAV, and flu vaccination or natural infections may have a protective effect against COVID-19 related mortality.

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Can Hepatitis A Vaccine Provide Protection Against COVID-19?

Cited by 17 publications

References 0 publications

Comparison of clinical features and laboratory findings of coronavirus disease 2019 and influenza A and B infections in children: a single-center study

Comparison of clinical features and laboratory findings of coronavirus disease 2019 and influenza A and B infections in children: a single-center study

COVID-19 Social Vaccine Toolkit(C19-SVT)

COVID-19 Disease and Interferon-γ: Has it a Protective Impact on Mortality?

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