Can fruit seeds and undigested plant residuals cause acute appendicitis

Engin, Ömer; Yıldırım, Mehmet; Yakan, Savaş; Coskun, Gulnihal Ay

doi:10.1016/s2221-1691(11)60004-x

Cited by 15 publications

(11 citation statements)

References 12 publications

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“…In most cases, no obstruction can be found [13]. In one study, only in 0.4% of 1969 appendectomy specimens was there evidence of luminal obstruction by vegetable fibers [14].…”

Section: Discussionmentioning

confidence: 99%

A Th2 Cytokine Profile in Appendicular Lavage Fluid Suggests Allergy as a Possible Etiology for Acute Appendicitis

Carvalho

Barros

Coelho

et al. 2019

Mediators of Inflammation

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Acute appendicitis is the most frequent surgical abdominal emergency, but its etiology remains poorly understood. Histological examination of the appendix, following its removal due to acute appendicitis, consistently shows features in common with bronchial asthma, suggesting an allergic reaction as a candidate etiologic factor. Here, we propose the concept of appendicular lavage and use it to study the levels of the Th2 cytokines IL-4, IL-5, and IL-9 in patients with a clinical diagnosis of acute appendicitis. The study group included 20 patients with a histological diagnosis of phlegmonous appendicitis, 13 patients with gangrenous appendicitis, and a control group of 8 patients with a clinical diagnosis of appendicitis but with normal histology. Cytokine levels were higher in acute appendicitis. The difference was more pronounced when comparing phlegmonous appendicitis with nonpathological appendicitis (p = 0.01) for IL-4 (48.3 vs. 21.3 pg/mL), IL-5 (29.2 vs. 8.0 pg/mL), and IL-9 (34.1 vs. 16.6 pg/mL). This Th2 cytokine profile is compatible with the hypothesis of allergy as an etiologic factor for acute appendicitis and may have important implications for the diagnosis, prevention, and treatment of this condition.

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“…In most cases, no obstruction can be found [13]. In one study, only in 0.4% of 1969 appendectomy specimens was there evidence of luminal obstruction by vegetable fibers [14].…”

Section: Discussionmentioning

confidence: 99%

A Th2 Cytokine Profile in Appendicular Lavage Fluid Suggests Allergy as a Possible Etiology for Acute Appendicitis

Carvalho

Barros

Coelho

et al. 2019

Mediators of Inflammation

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“…Furthermore, there are also few reports of bezoars obstructing the appendiceal lumen causing appendicitis [12]. …”

Section: Discussionmentioning

confidence: 99%

“…Although clinical presentations of bezoars are unusual, there have been reports of foreign body ingestion mimicking other diseases such as renal stones and irritable bowel syndrome [ 11 ]. Furthermore, there are also few reports of bezoars obstructing the appendiceal lumen causing appendicitis [ 12 ].…”

Section: Discussionmentioning

confidence: 99%

Rare Appendicitis-Like Syndrome: The Case of the Obstructing Broccoli

Jones

Narh-Martey

Patel

et al. 2014

Case Reports in Medicine

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The diagnosis of acute appendicitis can be somewhat obscure in a patient that presents with right lower quadrant abdominal pain. The advancement and ease of imaging have made CT scanning readily available in the emergency department. Management can be challenging when the patient has a high likelihood of appendicitis based on clinical suspicion and negative CT scan. The purpose of this case report is to demonstrate how an obstructing bezoar caused an appendicitis-like syndrome in a patient with negative CT scan and clinical diagnosis of acute appendicitis. This case report will discuss the appendicitis-like syndrome of an obstructing bezoar and an approach at management.

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“…Foreign bodies are known to constitute a cause of appendicitis, and, among the plethora of possible objects, seeds are the third most frequent. Although seeds constitute a potential cause of appendicitis (0.05% of appendectomies), they are rarely found within the lumen. The incidental presence of seeds within the appendix lumen may be challenging to interpret for junior or inexperienced pathologists.…”

mentioning

confidence: 99%