Can adjusting BMI for age and sex provide for a better predictor of colonic neoplasia?

Abstract

The association between BMI and adenoma differs by age and sex. If BMI is utilized to refine screening practices for colorectal cancer, its influence on sex and age should be taken into account.

Colonoscopy Findings in HIV-Infected Men and Women from an Urban U.S. Cohort Compared with Non-HIV-Infected Men and Women

“…In fact, the earliest study had only 45.5% of HIV-infected individuals with suppressed viral load while the present study had 83% with an HIV-1 RNA of less than 500 copies/mm 3 (17). Furthermore, the median CD4 cell count in earlier studies was 346 cells/mm 3 developing due to weight loss associated with uncontrolled HIV infection (25)(26)(27)(28). Likewise, the lower prevalence of diabetes mellitus in the HIV-infected patients did not account for the lower prevalence of colorectal neoplasms in HIV-infected patients because even when diabetes was controlled for there was still a lower risk in HIV-infected patients.…”

Single nucleotide polymorphism rs4648298 in miRNAs hsa-miR21 and hsa-miR590 binding site of COX gene is a strong colorectal cancer determinant

“…Single nucleotide polymorphism rs4648298 in miRNAs hsa-miR21 and hsa-miR590 binding site of COX gene is a strong colorectal cancer determinant lifestyle factors such as high body mass index (BMI), smoking, low activity and alcohol drinking increase the risk of CRC (5,6). Albeit, from all people who are exposed to same risk factors just some of them developed CRC.…”