Campylobacteriosis in returning travellers and potential secondary transmission of exotic strains

Mughini‐Gras, Lapo; Smid, Joost; Wagenaar, Jaap A.; Boer, A. De; Havelaar, Arie H.; Friesema, Ingrid; French, Nigel P.; Graziani, Caterina; Busani, Luca; Pelt, Wilfrid van

doi:10.1017/s0950268813002069

Cited by 38 publications

(30 citation statements)

References 42 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Furthermore, a study conducted in New Zealand that combined detailed epidemiological and genotyping data concluded that person-to-person transmission was responsible for 4% of campylobacteriosis cases in that country (74). Other studies, conducted in Australia and the Netherlands, provided similar figures for the contribution of person-to-person transmission to campylobacteriosis (300,379).…”

Section: Other Sourcesmentioning

confidence: 96%

Global Epidemiology of Campylobacter Infection

et al. 2015

View full text Add to dashboard Cite

SUMMARY Campylobacter jejuni infection is one of the most widespread infectious diseases of the last century. The incidence and prevalence of campylobacteriosis have increased in both developed and developing countries over the last 10 years. The dramatic increase in North America, Europe, and Australia is alarming, and data from parts of Africa, Asia, and the Middle East indicate that campylobacteriosis is endemic in these areas, especially in children. In addition to C. jejuni , there is increasing recognition of the clinical importance of emerging Campylobacter species, including Campylobacter concisus and Campylobacter ureolyticus . Poultry is a major reservoir and source of transmission of campylobacteriosis to humans. Other risk factors include consumption of animal products and water, contact with animals, and international travel. Strategic implementation of multifaceted biocontrol measures to reduce the transmission of this group of pathogens is paramount for public health. Overall, campylobacteriosis is still one of the most important infectious diseases that is likely to challenge global health in the years to come. This review provides a comprehensive overview of the global epidemiology, transmission, and clinical relevance of Campylobacter infection.

show abstract

Section: Other Sourcesmentioning

confidence: 96%

Global Epidemiology of Campylobacter Infection

et al. 2015

View full text Add to dashboard Cite

show abstract

“…While genomic signatures of host association can transcend geographical structuring within C. jejuni and C. coli populations, there can be differences in the genotypes that are isolated from different countries (Asakura et al., ; Islam et al., ; Kivisto et al., ; Mohan et al., ; Prachantasena et al., ). This presents challenges, not only for attributing the source of infections among travellers returning from foreign locations (Mughini‐Gras et al., ), but also for understanding disease epidemiology in the context of a global food industry.…”

Section: Discussionmentioning

confidence: 99%

“…The variable outer membrane protein gene porA , which has been used as part of extended MLST schemes (Cody, Maiden, & Dingle, ; Dingle, McCarthy, Cody, Peto, & Maiden, ) was also among those genes with evidence of elevated recombination. This may explain why weak allopatric signals have been associated with sequence variation in the porA gene in addition to source attribution signals (Mughini‐Gras et al., ; Sheppard, Colles et al., ; Smid et al., ).…”

Section: Discussionmentioning

confidence: 99%

Local genes for local bacteria: Evidence of allopatry in the genomes of transatlantic Campylobacter populations

et al. 2017

View full text Add to dashboard Cite

The genetic structure of bacterial populations can be related to geographical locations of isolation. In some species, there is a strong correlation between geographical distance and genetic distance, which can be caused by different evolutionary mechanisms. Patterns of ancient admixture in Helicobacter pylori can be reconstructed in concordance with past human migration, whereas in Mycobacterium tuberculosis it is the lack of recombination that causes allopatric clusters. In Campylobacter, analyses of genomic data and molecular typing have been successful in determining the reservoir host species, but not geographical origin. We investigated biogeographical variation in highly recombining genes to determine the extent of clustering between genomes from geographically distinct Campylobacter populations. Whole‐genome sequences from 294 Campylobacter isolates from North America and the UK were analysed. Isolates from within the same country shared more recently recombined DNA than isolates from different countries. Using 15 UK/American closely matched pairs of isolates that shared ancestors, we identify regions that have frequently and recently recombined to test their correlation with geographical origin. The seven genes that demonstrated the greatest clustering by geography were used in an attribution model to infer geographical origin which was tested using a further 383 UK clinical isolates to detect signatures of recent foreign travel. Patient records indicated that in 46 cases, travel abroad had occurred <2 weeks prior to sampling, and genomic analysis identified that 34 (74%) of these isolates were of a non‐UK origin. Identification of biogeographical markers in Campylobacter genomes will contribute to improved source attribution of clinical Campylobacter infection and inform intervention strategies to reduce campylobacteriosis.

show abstract

“…The variable outer membrane protein gene porA, which has been used as part of extended MLST schemes , Cody et al, 2009 was also among those genes with evidence of elevated recombination. This may explain why weak allopatric signals have been associated with sequence variation in the porA gene in addition to source attribution signals (Sheppard et al, 2010a, Smid et al, 2013, Mughini-Gras et al, 2014.…”

Section: (A) (B)mentioning

confidence: 99%

Local genes for local bacteria: evidence of allopatry in the genomes of transatlantic Campylobacter populations

Pascoe

Méric

Yahara

et al. 2016

Preprint

View full text Add to dashboard Cite

35The genetic structure of bacterial populations can be related to geographical locations of 36 isolation. In some species, there is a strong correlation between geographical distance and 37 genetic distance, which can be caused by different evolutionary mechanisms. Patterns of 38 ancient admixture in Helicobacter pylori can be reconstructed in concordance with past 39 human migration, whereas in Mycobacterium tuberculosis it is the lack of recombination that 40 causes allopatric clusters. In Campylobacter, analyses of genomic data and molecular typing 41 have been successful in determining the reservoir host species, but not geographical origin. 42We investigated biogeographical variation in highly recombining genes to determine the

show abstract

Campylobacteriosis in returning travellers and potential secondary transmission of exotic strains

Cited by 38 publications

References 42 publications

Global Epidemiology of Campylobacter Infection

Global Epidemiology of Campylobacter Infection

Local genes for local bacteria: Evidence of allopatry in the genomes of transatlantic Campylobacter populations

Local genes for local bacteria: evidence of allopatry in the genomes of transatlantic Campylobacter populations

Contact Info

Product

Resources

About