Campylobacter jejuni: A brief overview on pathogenicity-associated factors and disease-mediating mechanisms

Dasti, Javid Iqbal; Tareen, Abdul Malik; Lugert, Raimond; Zautner, Andreas E.; Groß, Uwe

doi:10.1016/j.ijmm.2009.07.002

Cited by 350 publications

(297 citation statements)

References 76 publications

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“…Campylobacteriosis is assumed to be mainly a food-borne disease (Dasti et al, 2010;Doorduyn et al, 2010;Man, 2011). In the present study from the data presented in Table 2, it is clear that the incidence of C. jejuni identified by traditional method within three year from 2012-2014 was highest in case of samples collected from chicken farms water (14.8%) followed by chicken intestine (12.8%) then raw chicken meat (9.6%).…”

Section: Discussionmentioning

confidence: 49%

“…Furthermore differences in weather between Governorates; warm weather may have triggered recreational activities with enhanced exposure to possible risk factors, for example consumption of undercooked chicken meat (Doorduyn et al, 2010) or swimming in contaminated water (Dasti et al, 2010). In Germany, Campylobacter incidence peaks both in rural as well as urban areas in the summer (Schielke et al, 2014).…”

Section: Discussionmentioning

confidence: 99%

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Public Health Hazard of Zoonotic Campylobacter jejuni Reference to Egyptian Regional and Seasonal Variations

Omara¹,

Fadaly²,

Barakat³

2015

Research J. of Microbiology

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Several Campylobacter species are known to be pathogenic to humans, with Campylobacter jejuni being the main leading cause of campylobacteriosis worldwide. The present investigation aimed to detect C. jejuni from chicken, water, milk and milk products and humans among 4 Egyptian Governorates (Cairo, Fayoum, Minya and Qalubiya) using conventional method and PCR 146 C. jejuni isolates with an incidence of 6.2% were confirmed to species level by polymerase chain reaction through detection of MapA gene. high incidence of C. jejuni was recorded in chicken intestine (12.8%) followed by Chicken farms water (12%), raw chicken meat (9.6%), occupational human workers stool samples (8.4%) then raw milk (2%), Quraish cheese (1.7%) and finally it was 1.2% in yoghourt. The PCR was definitive, reliable method that facilitated rapid identification of C. jejuni to the species level. It concluded that poor hygiene and sanitation in poultry farms could explain this high level of prevalence of C. jejuni among the examined samples.

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Section: Discussionmentioning

confidence: 49%

Section: Discussionmentioning

confidence: 99%

Public Health Hazard of Zoonotic Campylobacter jejuni Reference to Egyptian Regional and Seasonal Variations

Omara¹,

Fadaly²,

Barakat³

2015

Research J. of Microbiology

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“…Campylobacter jejuni is the leading cause of bacterial gastroenteritis and food-borne disease in the Western world and accounts for 5% of food-related deaths (1,2). In addition, C. jejuni infection is strongly associated with Guillain-Barré syndrome, a rapidly ascending paralysis, as well as inflammatory bowel disease and reactive arthritis (3,4).…”

mentioning

confidence: 99%

“…1 H NMR spectra were collected using a 2-s presaturation pulse for products P5 and P6, or WET sequence (36) for P3, centered on the residual HDO resonance.…”

mentioning

confidence: 99%

Complete 6-Deoxy-d-altro-heptose Biosynthesis Pathway from Campylobacter jejuni

McCallum

Shaw

et al. 2012

Journal of Biological Chemistry

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“…Putative pathogenicity associated factors of C. jejuni include genes for motility and chemotaxis, binding and adhesion, as well as invasion and toxins [53]. The C. jejuni NCTC 11168 luxS mutant showed no differences in adherence to and invasion of cultured Caco-2 cells as compared to the wild type strain [32].…”

Section: Virulence Factors and Pathogenicitymentioning

confidence: 95%

Quorum sensing dependent phenotypes and their molecular mechanisms inCampylobacterales

Gölz¹,

Sharbati²,

Backert³

et al. 2012

European Journal of Microbiology and Immunology

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Quorum sensing comprises the mechanism of communication between numerous bacteria via small signalling molecules, termed autoinducers (AI). Using quorum sensing, bacteria can regulate the expression of multiple genes involved in virulence, toxin production, motility, chemotaxis and biofilm formation, thus contributing to adaptation as well as colonisation. The current understanding of the role of quorum sensing in the lifecycle of Campylobacterales is still incomplete. Campylobacterales belong to the class of Epsilonproteobacteria representing a physiologically and ecologically diverse group of bacteria that are rather distinct from the more commonly studied Proteobacteria, such as Escherichia and Salmonella. This review summarises the recent knowledge on distribution and production of AI molecules, as well as possible quorum sensing dependent regulation in the mostly investigated species within the Campylobacterales group: Campylobacter jejuni and Helicobacter pylori.

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Campylobacter jejuni: A brief overview on pathogenicity-associated factors and disease-mediating mechanisms

Cited by 350 publications

References 76 publications

Public Health Hazard of Zoonotic Campylobacter jejuni Reference to Egyptian Regional and Seasonal Variations

Public Health Hazard of Zoonotic Campylobacter jejuni Reference to Egyptian Regional and Seasonal Variations

Complete 6-Deoxy-d-altro-heptose Biosynthesis Pathway from Campylobacter jejuni

Quorum sensing dependent phenotypes and their molecular mechanisms inCampylobacterales

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