Camel trypanosomosis in the Canary Islands: assessment of seroprevalence and infection rates using the card agglutination test (CATT/T. evansi) and parasite detection tests

Gutiérrez, Carlos; Juste, M.C.; Corbera, Juan Alberto; Magnus, E; Verloo, Didier; Montoya, J. A.

doi:10.1016/s0304-4017(00)00225-9

Cited by 58 publications

(35 citation statements)

References 3 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…All RoTat 1.2 VSG‐based diagnostic tests seem to have a good analytical sensitivity since all T. evansi strains tested positive consistently in all tests. Diagnostic sensitivity from the tests mentioned above was evaluated for T. evansi infections in water buffaloes7 and camels 8,9. Judging from the data obtained and from practical use in the field, the RoTat 1.2 VSG seemed to be a useful antigen in screening tests.…”

Section: Discussionmentioning

confidence: 99%

Expression of RoTat 1.2 Cross‐reactive Variable Antigen Type in Trypanosoma evansi and T. equiperdum

Claes¹,

Verloo²,

Waal³

et al. 2002

Annals of the New York Academy of Sciences

View full text Add to dashboard Cite

The variable antigen type (VAT) RoTat 1.2 has been cloned from a T. evansi strain, isolated in 1982 from a water buffalo in Indonesia. All T. evansi isolates hitherto tested express this VAT. In a study on the differential diagnosis of T. equiperdum and T. evansi in horses, we investigated serological evidence for the expression of RoTat 1.2 in 11 T. evansi and six T. equiperdum populations originating from Asia, Europe, Africa, and the Americas. Preinfection sera and sera of days 7, 14, 25, and 35 post-infection (p.i.) were analyzed for the presence of antibodies reactive with RoTat 1.2 in immune trypanolysis, ELISA/T. evansi and CATT/T. evansi. Within the duration of the experiment, all rabbits infected with T. evansi became positive in the three serological tests. Five out of six rabbits infected with T. equiperdum also became positive in the three tests. Only one T. equiperdum strain (the OVI strain from South Africa) did not induce the production of antibodies reactive with RoTat 1.2 and thus might not contain or express a VSG that shares epitopes similar to those on the RoTat 1.2 VSG. The data lead to the conclusion that T. equiperdum can express VSGs containing epitopes serologically similar to those in the T. evansi RoTat 1.2 VAT. This explains, in part, why the antibody detection tests based on Ro Tat 1.2 VSG cannot reliably distinguish between the infections caused by T. evansi and those caused by T. equiperdum. There are no data that contradict the possibility that the putative T. equiperdum strains, which express VSGs with epitopes similar to those on RoTat 1.2, are actually T. evansi.

show abstract

Section: Discussionmentioning

confidence: 99%

Expression of RoTat 1.2 Cross‐reactive Variable Antigen Type in Trypanosoma evansi and T. equiperdum

Claes¹,

Verloo²,

Waal³

et al. 2002

Annals of the New York Academy of Sciences

View full text Add to dashboard Cite

show abstract

“…The CATT/T. evansi, a direct agglutination test, is the most widely applied test and has a proven record of reliability for different host species, such as buffaloes and camels (6,7). An indirect latex agglutination test for T. evansi also has been used successfully with several host species but is less widely used (22).…”

Section: Discussionmentioning

confidence: 99%

Towards a New Reference Test for Surra in Camels

Tran

Claes

Verloo

et al. 2009

Clin Vaccine Immunol

View full text Add to dashboard Cite

show abstract

“…In all cases, the potential for T. evansi to invade and establish as enzootic disease in Australia, Japan, or even Europe is a true and real threat. Trypanosoma evansi was introduced into the Canary Islands, most probably from Mauritania or Mali, in camels, and has yet to be eradicated [37, 100, 101]; from there it was introduced into continental Spain and France [40, 41]. In France it was controlled early and eradicated, but in Spain the situation remains unclear since camels, and also horses, were involved in the Alicante province [39, 102].…”

Section: The Large Host Range Of T Evansimentioning

confidence: 99%

Trypanosoma evansiand Surra: A Review and Perspectives on Origin, History, Distribution, Taxonomy, Morphology, Hosts, and Pathogenic Effects

Desquesnes

Holzmüller

Lai

et al. 2013

BioMed Research International

339

327

View full text Add to dashboard Cite

Trypanosoma evansi, the agent of “surra,” is a salivarian trypanosome, originating from Africa. It is thought to derive from Trypanosoma brucei by deletion of the maxicircle kinetoplastic DNA (genetic material required for cyclical development in tsetse flies). It is mostly mechanically transmitted by tabanids and stomoxes, initially to camels, in sub-Saharan area. The disease spread from North Africa towards the Middle East, Turkey, India, up to 53° North in Russia, across all South-East Asia, down to Indonesia and the Philippines, and it was also introduced by the conquistadores into Latin America. It can affect a very large range of domestic and wild hosts including camelids, equines, cattle, buffaloes, sheep, goats, pigs, dogs and other carnivores, deer, gazelles, and elephants. It found a new large range of wild and domestic hosts in Latin America, including reservoirs (capybaras) and biological vectors (vampire bats). Surra is a major disease in camels, equines, and dogs, in which it can often be fatal in the absence of treatment, and exhibits nonspecific clinical signs (anaemia, loss of weight, abortion, and death), which are variable from one host and one place to another; however, its immunosuppressive effects interfering with intercurrent diseases or vaccination campaigns might be its most significant and questionable aspect.

show abstract

Camel trypanosomosis in the Canary Islands: assessment of seroprevalence and infection rates using the card agglutination test (CATT/T. evansi) and parasite detection tests

Cited by 58 publications

References 3 publications

Expression of RoTat 1.2 Cross‐reactive Variable Antigen Type in Trypanosoma evansi and T. equiperdum

Expression of RoTat 1.2 Cross‐reactive Variable Antigen Type in Trypanosoma evansi and T. equiperdum

Towards a New Reference Test for Surra in Camels

Trypanosoma evansiand Surra: A Review and Perspectives on Origin, History, Distribution, Taxonomy, Morphology, Hosts, and Pathogenic Effects

Contact Info

Product

Resources

About