“…Several cross-sectional studies have investigated the association of energy intake with the incidence of frailty and cognitive impairment in older individuals. Lower total energy intake was associated with higher prevalence of sarcopenia [118] and cognitive impairment [119]. In the Rotterdam study, the risk of frailty decreased approximately by 5% with each 418.4 kJ (100 kcal) increase in total energy intake [120].…”
The increasing prevalence of older adults with diabetes has become a major social burden. Diabetes, frailty, and cognitive dysfunction are closely related to the mechanisms of aging. Insulin resistance, arteriosclerosis, chronic inflammation, oxidative stress, and mitochondrial dysfunction may be common mechanisms shared by frailty and cognitive impairment. Hyperglycemia, hypoglycemia, obesity, vascular factors, physical inactivity, and malnutrition are important risk factors for cognitive impairment and frailty in older adults with diabetes. The impact of nutrients on health outcomes varies with age; thus, shifting diet therapy strategies from the treatment of obesity/metabolic syndrome to frailty prevention may be necessary in patients with diabetes who are over 75 years of age, have frailty or sarcopenia, and experience malnutrition. For the prevention of frailty, optimal energy intake, sufficient protein and vitamin intake, and healthy dietary patterns should be recommended. The treatment of diabetes after middle age should include the awareness of proper glycemic control aimed at extending healthy life expectancy with proper nutrition, exercise, and social connectivity. Nutritional therapy in combination with exercise, optimal glycemic and metabolic control, and social participation/support for frailty prevention can extend healthy life expectancy and maintain quality of life in older adults with diabetes mellitus.
“…Several cross-sectional studies have investigated the association of energy intake with the incidence of frailty and cognitive impairment in older individuals. Lower total energy intake was associated with higher prevalence of sarcopenia [118] and cognitive impairment [119]. In the Rotterdam study, the risk of frailty decreased approximately by 5% with each 418.4 kJ (100 kcal) increase in total energy intake [120].…”
The increasing prevalence of older adults with diabetes has become a major social burden. Diabetes, frailty, and cognitive dysfunction are closely related to the mechanisms of aging. Insulin resistance, arteriosclerosis, chronic inflammation, oxidative stress, and mitochondrial dysfunction may be common mechanisms shared by frailty and cognitive impairment. Hyperglycemia, hypoglycemia, obesity, vascular factors, physical inactivity, and malnutrition are important risk factors for cognitive impairment and frailty in older adults with diabetes. The impact of nutrients on health outcomes varies with age; thus, shifting diet therapy strategies from the treatment of obesity/metabolic syndrome to frailty prevention may be necessary in patients with diabetes who are over 75 years of age, have frailty or sarcopenia, and experience malnutrition. For the prevention of frailty, optimal energy intake, sufficient protein and vitamin intake, and healthy dietary patterns should be recommended. The treatment of diabetes after middle age should include the awareness of proper glycemic control aimed at extending healthy life expectancy with proper nutrition, exercise, and social connectivity. Nutritional therapy in combination with exercise, optimal glycemic and metabolic control, and social participation/support for frailty prevention can extend healthy life expectancy and maintain quality of life in older adults with diabetes mellitus.
“…The CERAD-K initially consisted of eight tests (Verbal Fluency, Modified Boston Naming, Mini-Mental State Examination (MMSE-KC), Word List Memory, Constructional Praxis, Word List Recall, Word List Recognition, and Constructional Praxis Recall). However, Word List Memory/Recall/Recognition, 7-Digit Span (forward, backward), Trail Making Test A(TMT-A), and MMSE-KC are included in this study [ 18 ].…”
This study aimed to analyze the effect of the COVID-19 pandemic on cognitive function of community-dwelling elderly individuals. Five-year (2016 to 2020) longitudinal data of the Korea Frailty and Aging Cohort Study (KFACS) were used. There were 1559 participants in 2016 and 1455 in 2017 aged 72–84 years. Follow-up was conducted at two-year intervals. We selected participants from the database of the 2017 and 2018 surveys for intergroup comparison over 2-year follow-ups. The number of study patients in the 2017-Group was 1027 and that of the 2018-Group was 879. In the intergroup comparison, the mean difference of word list memory score from 2018 to 2020 was −0.14, while that from 2017 to 2019 was 0.53. The mean difference of word list recall score from 2018 to 2020 was −0.25, while that from 2017 to 2019 was 0.03. These were significant even after adjusting confounding variables. In the intragroup comparison, the word list memory and recall scores from 2018 to 2020 were more decreased than those from 2016 to 2018. Conclusively, cognitive function of the Korean elderly cohort declined much more during the COVID-19 pandemic than before the pandemic, particularly in terms of memory and recall function.
“…The CERAD-K is a standardized clinical and neuropsychological assessment battery for the evaluation of patients with Alzheimer's disease. The CERAD-K consists of eight tests (verbal fluency, modified Boston naming, MMSE, word list memory, constructional praxis, word list recall, word list recognition, and constructional praxis recall); however, in this study, word list memory/recall/recognition, digit span (forward and backward), the trail-making test (TMT) A, and the MMSE were included [22].…”
Section: Depressionmentioning
confidence: 99%
“…The participants are given digits at a rate of one digit per sec and had to repeat numbers in the reverse order. The score is the total number of correct items [22]; •…”
mentioning
confidence: 99%
“…The Trail-Making Test: evaluates attention, ordering, executive function, time-space search, and mental motion velocity. The participants were asked to draw a line connecting the numbers from 1 to 25 in ascending order, and the time (s) was recorded [22]; • Time-orientation test: as a test that constitutes the MMSE, it evaluates the participants' temporal orientation by asking five questions; "What year is it? ", "What month is it?…”
Mild cognitive impairment (MCI) and depression are common and frequently misdiagnosed in older adults in primary care. In particular, depression combined with cognitive dysfunction is associated with a higher risk of dementia. We tried to find the usefulness of orientation to time as an easy case-finding tool for suspecting MCI or depression. This cross-sectional study included 2668 community-dwelling adults aged 70–84 years from the Korean Frailty and Aging Cohort Study (mean age of 76.0 ± 3.9 years). MCI was defined based on the criteria from the National Institute on Aging and the Alzheimer’s Association; depression was defined as a score of ≥ 6 on the Geriatric Depression Scale—Short Form (GDS-SF). Time orientation to year, month, day of the week, date, and season were tested. The sensitivity for the diagnosis of each of MCI and depression was the highest for the orientation to year (MCI, 17.7%; depression, 16.0%). For the diagnosis of MCI or depression, orientation to the year had the highest sensitivity (15.5%), and the specificity, PPV, NPV was 95.5%, 67.0%, 65.5%. In conclusion, asking “what year is it?” can be helpful as an aid to case finding to suspect MCI or depression in community and primary care settings.
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