Calculations of cardiovascular shunts and regurgitation using magnetic resonance ventricular volume and aortic and pulmonary flow measurements

Devos, Daniël; Kilner, Philip J.

doi:10.1007/s00330-009-1568-2

Cited by 54 publications

(38 citation statements)

References 26 publications

(24 reference statements)

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“…Quantitative flow measurements are an important element of cardiovascular MRI studies that are performed in patients with congenital heart disease (2)(3)(4)13,14). Therefore, the validation of novel 4D VEC MRI techniques is crucial for their successful introduction into clinical practice.…”

Section: Discussionmentioning

confidence: 99%

“…Quantitative flow assessment is an important element of cardiovascular MRI studies in patients with congenital heart disease and, in many cases, information about blood flow is required in multiple arterial and venous vessels (2)(3)(4). However, repeat planning and acquisition of 2D VEC MRI can be time-consuming.…”

Section: Two-dimensional (2d) Velocity Encoded Cine Magnetic Resonancmentioning

confidence: 99%

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Flow‐sensitive four‐dimensional cine magnetic resonance imaging for offline blood flow quantification in multiple vessels: A validation study

Nordmeyer

Riesenkampff

Crelier

et al. 2010

Magnetic Resonance Imaging

101

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Purpose:To further validate the quantitative use of flowsensitive four-dimensional velocity encoded cine magnetic resonance imaging (4D VEC MRI) for simultaneously acquired venous and arterial blood flow in healthy volunteers and for abnormal flow in patients with congenital heart disease.Materials and Methods: Stroke volumes (SV) obtained in arterial and venous thoracic vessels were compared between standard two-dimensional (2D), 4D VEC MRI with and without respiratory navigator gating (gated/nongated) in volunteers (n ¼ 7). In addition, SV and regurgitation fractions (RF) measured in aorta or pulmonary trunk of patients with malformed and/or insufficient valves (n ¼ 10) were compared between 2D and nongated 4D VEC MRI methods. Results:In volunteers and patients, Bland-Altman tests showed excellent agreement between 2D, gated, and nongated 4D VEC MRI obtained quantitative blood flow measurements. The bias between 2D and gated 4D VEC MRI was <0.5 mL for SV; between 2D and nongated 4D VEC MRI the bias was <0.7 mL for SV and <1% for RF.Conclusion: Blood flow can be quantified accurately in arterial, venous, and pathological flow conditions using 4D VEC MRI. Nongated 4D VEC MRI has the potential to be suited for clinical use in patients with congenital heart disease who require flow acquisitions in multiple vessels.

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Section: Discussionmentioning

confidence: 99%

Section: Two-dimensional (2d) Velocity Encoded Cine Magnetic Resonancmentioning

confidence: 99%

Flow‐sensitive four‐dimensional cine magnetic resonance imaging for offline blood flow quantification in multiple vessels: A validation study

Nordmeyer

Riesenkampff

Crelier

et al. 2010

Magnetic Resonance Imaging

101

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“…MRI can also help to clarify the nature of the lesion, the amount of shunting [55], and biventricular size and function, and can detect associated anomalies, notably the possibility of anomalous pulmonary venous drainage [56][57][58]. Ascending aortic flow measured by MRI represents systemic flow (Q s ) when there is an intracardiac left-toright shunt.…”

Section: Shunts: Asd Vsd or Pdamentioning

confidence: 99%

Imaging congenital heart disease in adults

Kilner¹

2011

BJR

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ABSTRACT. Transthoracic echocardiography is the first-line modality for cardiovascular imaging in adults with congenital heart disease (ACHD). The windows of access that are possible with transthoracic echocardiography are, however, rarely adequate for all regions of interest. The choice of further imaging depends on the clinical questions that remain to be addressed. The strengths of MRI include comprehensive access and coverage, providing imaging of all parts of the right ventricle, the pulmonary arteries, pulmonary veins and aorta. Cine images and velocity maps are acquired in specifically aligned planes, with stacks of cines or dynamic contrast angiography providing more comprehensive coverage. Tissues can be characterised if necessary, and MRI provides relatively accurate measurements of biventricular function and volume flow. These parameters are important in the assessment and follow-up of adults after repairs for tetralogy of Fallot or transposition of the great arteries and after Fontan operations. The superior spatial resolution and rapid acquisition of CT are invaluable in selected situations, including the visualisation of anomalous coronary or aortopulmonary collateral arteries, the assessment of luminal patency after stenting and imaging in patients with pacemakers. Ionising radiation is, however, a concern in younger patients who may need repeated investigation. Adults with relatively complex conditions should ideally be imaged in a specialist ACHD centre, where dedicated echocardiographic and cardiovascular MRI services are a necessary facility. General radiologists should be aware of the nature and pathophysiology of congenital heart disease, and should be alert for previously undiagnosed cases presenting in adulthood, including cases of atrial septal defect, aortic coarctation, patent ductus arteriosus, double-chambered right ventricle and congenitally corrected transposition.

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“…For in vivo studies peak velocity, stroke volume (net forward volume) and regurgitant fraction were quantified as described in the literature [25]. For real-time measurements, variables were averaged over all evaluated heart cycles (at least ten) to account for the inherent averaging of conventional segmented acquisition.…”

Section: In Patients With Afib We Performed Rt Measurementsmentioning

confidence: 99%

Real-time phase contrast magnetic resonance imaging for assessment of haemodynamics: from phantom to patients

et al. 2015

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Calculations of cardiovascular shunts and regurgitation using magnetic resonance ventricular volume and aortic and pulmonary flow measurements

Abstract: This article aims to explain and illustrate the technical and theoretical basis for calculations using volumetric and flow measurements, providing formulae and diagrams to facilitate the interpretation of results.

Cited by 54 publications

References 26 publications

Flow‐sensitive four‐dimensional cine magnetic resonance imaging for offline blood flow quantification in multiple vessels: A validation study

Flow‐sensitive four‐dimensional cine magnetic resonance imaging for offline blood flow quantification in multiple vessels: A validation study

Imaging congenital heart disease in adults

Real-time phase contrast magnetic resonance imaging for assessment of haemodynamics: from phantom to patients

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