Calcium phosphate thin films synthesized by pulsed laser deposition: Physico-chemical characterization and in vitro cell response

Mihăilescu, I. N.; Torricelli, Paola; Bigi, Adriana; Mayer, I.; Iliescu, M.; Werckmann, J.; Socol, G.; Miroiu, F.; Cuisinier, Frédéric; Elkaïm, R.; Hildebrand, Gerhard

doi:10.1016/j.apsusc.2005.03.111

Cited by 36 publications

(22 citation statements)

References 16 publications

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“…Comparison of the materials composed of OCP, HA and Mn-HA showed positive in vitro results. In addition, the experiments also showed potential application of OCP as a biomimetic material for implant coating [9].…”

Section: Introductionmentioning

confidence: 85%

Comparative study of hydroxyapatite and octacalcium phosphate coatings deposited on metallic implants by PLD method

et al. 2010

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The aim of the presented study was an analysis of two apatite coatings: hydroxyapatite (HA) and octacalcium phosphate (OCP) as coatings materials for metallic implants. Both layers were deposited by means of the PLD method. As a target material, synthetic, powdered and pressed hydroxyapatite was used. HA was deposited on 316L steel substrate in two temperature ranges for obtaining different coatings: 150 ± 30°C and 430 ± 30°C for OCP and HA, respectively. As an intermediate layer, the nanocrystalline diamond layer (NCD) was deposited. Examined calcium phosphate layers were tested for adhesion of osteoblast cell culture (MG-63). Analytical methods (AFM, FTIR) showed the usefulness of the PLD method for deposition of the apatite layers on metallic implants. Both examined layers showed biocompatibility with human osteoblast

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Section: Introductionmentioning

confidence: 85%

Comparative study of hydroxyapatite and octacalcium phosphate coatings deposited on metallic implants by PLD method

et al. 2010

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“…We will only focus on some of these techniques, based on laser, that present a strong potential for future application on bone implants. Laser-based coating methods can be used as well for depositing inorganic materials as organic materials like polymers but also biological molecules or cells [20][21][22][23]. The most used coatings on bone implants are the calcium phosphate-based (CaP) coatings.…”

Section: Physical Coatingsmentioning

confidence: 99%

Biomaterials and interface with bone

Anselme

2011

Osteoporos Int

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“…Hydroxyapatite coatings containing biologically relevant dopants may also be prepared using pulsed laser deposition. For example, Mihailescu et al used krypton fluoride excimer pulsed laser deposition to deposit crystalline manganese-doped carbonated hydroxyapatite coatings on titanium surfaces [39]. In vitro studies involving fibroblasts and osteoblasts indicated excellent adherence and biocompatibility of this material.…”

Section: Laser Processing Of Biomaterialsmentioning

confidence: 99%

Laser Engineering of Surface Structures

Narayan

Goering

Balani³

et al. 2014

Biosurfaces

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Over the past half century, rapid progress has been made in laser-based medical diagnosis and treatment, as well as in laser-based medical device fabrication. Lasers have unique capabilities for coating, machining, melting, polymerizing, sintering, and welding materials that are used in implantable and transdermal medical devices. In this review, academic and industrial developments involving laser processing of materials for dental, orthopedic, neural, ophthalmic, cardiovascular and transdermal applications are described. In addition, laser processing of nanoscale materials for medical applications is discussed. Finally, the challenges associated with commercialization of laser biomaterials are considered. Due to the unique capabilities provided by laser-based processes, it is anticipated that the use of laser biomaterials in implantable and transdermal medical devices will markedly increase over the coming years.

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Calcium phosphate thin films synthesized by pulsed laser deposition: Physico-chemical characterization and in vitro cell response

Cited by 36 publications

References 16 publications

Comparative study of hydroxyapatite and octacalcium phosphate coatings deposited on metallic implants by PLD method

Comparative study of hydroxyapatite and octacalcium phosphate coatings deposited on metallic implants by PLD method

Biomaterials and interface with bone

Laser Engineering of Surface Structures

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