Calcium carbonate biomineralization utilizing a multifunctional β-sheet peptide template

Abstract

We designed a novel multifunctional β-sheet peptide template for calcium carbonate mineralization. The template self-supplies the mineral source, a carbonate ion, by hydrolysis of urea, and regulates the crystal phase and morphology of the obtained calcium carbonate.

Hydroxyapatite Formation on Self-Assembling Peptides with Differing Secondary Structures and Their Selective Adsorption for Proteins

“…Xu et al revealed that control of morphology and size of nanostructures were observed by using a self-assembling peptide template. In addition, our group previously showed that the morphologies of inorganic materials are controlled on a self-assembling peptide template [30,31,32,33] and elucidated that the secondary structures of peptides have a great impact on the resulting particles.…”

Efficient enzyme encapsulation inside sol-gel silica sheets prepared by poly-L-lysine as a catalyst

“…One extensively study is the biomineralization of highly ordered biosilica from alkoxysilane such as tetramethoxysilane (TMOS) and tetraethoxysilane (TEOS) using biomolecules (e.g., peptides, proteins, and nucleic acids); this system offers precise control the nanostructure of the obtained inorganic material [26][27][28][29][30]. In addition, polyamines and polypeptides (like poly-L -lysine) can catalyze silicic acid deposition [31][32][33][34][35]. Interestingly, Tomczak et al [36] determined that poly-L -lysine with an α-helix conformation precipitated to form hexagonal silica platelets.…”

Regulated Drug Release Abilities of Calcium Carbonate–Gelatin Hybrid Nanocarriers Fabricated via a Self‐Organizational Process

“…However, this involves many steps in the process of their fabrication. With this in mind, in our previous study, we focused on biomineralization, which involves the fabrication of functional materials via a single process . Biomineralization controls the morphology, crystal phase, and functionality of mineralized inorganic matters (e.g., calcium carbonate, calcium phosphate, and silica) via the nanostructure of the organic template surface (e.g., protein or polysaccharide) .…”

“…With this in mind, in our previous study,w ef ocused on biomineralization, which involves the fabrication of functional materials via as ingle process. [13][14][15][16][17][18][19][20][21] Biomineralization controlst he morphology,c rystal phase, and functionality of mineralized inorganic matters( e.g.,c alcium carbonate, calcium phosphate, and silica) via the nanostructure of the organic template surface (e.g.,p rotein or polysaccharide). [22] Collagen is at ypical organic template that has gained interesti ns everal fields of research asafunctional material with aw ide variety of functions.…”