Caftaric Acid Isolation from Unripe Grape: A “Green” Alternative for Hydroxycinnamic Acids Recovery

Vendramin, Veronica; Viel, Alessia; Vincenzi, Simone

doi:10.3390/molecules26041148

Cited by 12 publications

(7 citation statements)

References 37 publications

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“…The anti-aging effect of extracts from C.L. is probably the result of the action of the compounds present in these extracts with proven ability to inhibit the activity of collagenase and elastase, such as gallic acid, quercetin 3-glucuronide, quinic acid, ellagic acid and caftaric acid [50][51][52][53].…”

Section: Assessment Of Matrix Metallopeptidase Inhibition Using Elisa...mentioning

confidence: 99%

Evaluation of the Biological Activity of Hydrogel with Cornus mas L. Extract and Its Potential Use in Dermatology and Cosmetology

Zagórska-Dziok,

Ziemlewska,

Mokrzyńska

et al. 2023

Molecules

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Due to the growing popularity of herbal extract-loaded hydrogels, this study assessed the biological activity of extracts and hydrogels containing three types (water (WE), water–ethanol (EE) and water–glycerin (GE)) of Cornus mas L. (dogwood) extracts. The content of biologically active compounds in the extracts was assessed using the UPLC-DAD-MS technique. Antioxidant properties were assessed by using DPPH and ABTS radicals and measuring the intracellular level of reactive oxygen species. Alamar Blue and Neutral Red tests were used to measure the cytotoxicity of the tested samples on skin cells—fibroblasts and keratinocytes. Cell migration and the anti-aging activity of the tested extracts and hydrogels were assessed. Transepidermal water loss and skin hydration after applying the hydrogels to the skin were also determined. A chromatographic analysis revealed that the extracts contained polyphenols, including gallic, caftaric, protocatechuic, chlorogenic, ellagic and p-coumaroylquinic acids, as well as iridoids, with loganic acid as the predominant component. Additionally, they contained cyanidin 3-O-galactoside, pelargonidin 3-O-glucoside and quinic acid. The obtained results show that the tested extracts and hydrogels had strong antioxidant properties and had a positive effect on the viability of skin cells in vitro. Additionally, it was shown that they stimulated the migration of these cells and had the ability to inhibit the activity of collagenase and elastase. Moreover, the tested hydrogels increased skin hydration and prevented transepidermal water loss. The obtained results indicate that the developed hydrogels may be effective delivery systems for phytochemicals contained in dogwood extracts.

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Section: Assessment Of Matrix Metallopeptidase Inhibition Using Elisa...mentioning

confidence: 99%

Evaluation of the Biological Activity of Hydrogel with Cornus mas L. Extract and Its Potential Use in Dermatology and Cosmetology

Zagórska-Dziok,

Ziemlewska,

Mokrzyńska

et al. 2023

Molecules

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“…Hydroxycinnamic acids are mainly found in grape pulp, and also present in skin, seeds and stems in variable amounts. Moreover, their concentration varies a lot between different tissues and different grape varieties [43,45,46]. The lower concentrations of caftaric acid, ferulic acid, and p-coumaric acid in GJ treatment confirm the presence of these compounds in grape pulp in very low concentrations in Pinot noir berries and/or these compounds are oxidised by endogenous tyrosinase when grapes are crushed [46].…”

Section: Monomeric Phenolics Compositionmentioning

confidence: 92%

Characterisation of Tannin and Aroma Profiles of Pinot Noir Wines Made with or without Grape Pomace

2022

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The contribution of grape pomace on tannin concentration, tannin composition and aroma profile of Pinot noir wine was studied using different fermentation media to make up four treatments: GJ-P, grape juice plus pomace; MJ-P, model juice plus pomace; GJ, grape juice; MJ, model juice. The MJ-P treatment showed significantly lower amounts of tannins, mean degree of polymerisation (mDP), similar amounts of anthocyanin, and a similar secondary aroma profile compared to the GJ-P treatment. Grape pomace addition significantly increased the tannin concentration in wines. This study was also revealed the importance of phenolics present in grape juice in tannin polymerisation and final tannin concentration in wines. Grape pomace addition significantly reduced some important aroma compounds such as acetate esters (except ethyl acetate), most of the volatile fatty acids, a few ethyl esters and β-damascenone but increased some primary aromas in wines due to the presence of their aroma precursors in skins. Hence, these results indicate that grape pomace may bind or delay the release of some aroma compounds and/or lose these compounds during cap management in GJ-P and MJ-P treatments compared to the respective juice treatments.

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“…The mass concentration of the polymer forms of phenolic substances was determined utilizing a colorimetric method, employing the Folin-Ciocalteu reagent by slightly modifying the method developed by Vendramin et al [17]. The grape berries were subjected to homogenization, with approximately 20 g diluted in 100 mL of deionized water.…”

Section: Analytical Methods For Phenolic Compoundsmentioning

confidence: 99%

Fine-Tuning Grape Phytochemistry: Examining the Distinct Influence of Oak Ash and Potassium Carbonate Pre-Treatments on Essential Components

Kaya,

Delavar,

Ates

et al. 2024

Horticulturae

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Understanding the impact of pre-treatment methods on the phytochemical composition of grapes is essential for optimizing grape quality and producing raisins with desirable characteristics. Therefore, this study meticulously analyzed the impact of two distinct pre-treatment methods, oak ash and potassium carbonate (K2CO3), on the composition of essential phytochemical components in grapes. This research encompassed phenolic compounds, anthocyanins, phenolic acids, flavonoids, and phytoalexins. This study investigates the impact of pre-treatment methods, oak ash and K2CO3, on the phytochemical composition of grapes. Significant differences were observed in anthocyanins, flavonoids, phytoalexins, and phenolic acids between the treatments. Oak ash exhibited advantages in preserving specific compounds, including higher levels of anthocyanins, flavonols, flavones, flavanones, catechins, resveratrol, pterostilbene, and viniferin, compared to K2CO3. Notably, the delphinidin-3-O-glycoside content was significantly higher in the oak ash treatment. An analysis of phenolic compounds revealed distinctions in hydroxycinnamic acids, hydroxybenzoic acids, benzaldehyde, and phenylacetaldehyde. Additionally, gallic acid, vanillic acid, trans-caffeic acid, trans-p-coumaric acid, and (-)-epicatechin were significantly more prevalent in the K2CO3 treatment, while ferulic acid and quercetin were more prevalent in the oak ash treatment. These findings underscore the pivotal role of pre-treatment methods in shaping the phytochemical content of grapes, thus holding critical implications for grape-derived products’ quality and potential health benefits.

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Caftaric Acid Isolation from Unripe Grape: A “Green” Alternative for Hydroxycinnamic Acids Recovery

Cited by 12 publications

References 37 publications

Evaluation of the Biological Activity of Hydrogel with Cornus mas L. Extract and Its Potential Use in Dermatology and Cosmetology

Evaluation of the Biological Activity of Hydrogel with Cornus mas L. Extract and Its Potential Use in Dermatology and Cosmetology

Characterisation of Tannin and Aroma Profiles of Pinot Noir Wines Made with or without Grape Pomace

Fine-Tuning Grape Phytochemistry: Examining the Distinct Influence of Oak Ash and Potassium Carbonate Pre-Treatments on Essential Components

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