Caffeine-withdrawal headache induced by hemodialysis

Dialysis Headache: A Narrative Review

“…Another study reported on a case of caffeine deprivation headache in association with hemodialysis . It seems unlikely that caffeine withdrawal alone could be the single cause of the headache, but could be contributing.…”

“…There are reports on responses to using chlorpromazine prior to dialysis and angiotensin‐converting enzyme inhibitors (fosinopril and lisinopril), nortriptyline, and magnesium oxide as prophylactic treatments . The recommendations have included volume maintenance, electrolyte and blood pressure control, and avoidance of overuse of caffeine …”

Hemodialysis‐related headache

“…Caffeine‐withdrawal headache is reported in patients consuming excessive amounts of caffeine in daily life. This situation, termed as caffeine‐withdrawal headache, is used for patients consuming more than 200 mg of caffeine per day for more than 2 weeks who experience bilateral and/or pulsatile headache within 24 hours after last caffeine intake and disappear within 1 hour after 100 mg caffeine intake . Caffeine‐withdrawal headache is described in a HD patient as well.…”

“…Caffeine‐withdrawal headache is described in a HD patient as well. Authors that report headache because of acceleration in caffeine elimination, normal half‐life of 2.5–4 hours, during HD mentioned that caffeine‐withdrawal headache has a genetic background as well . It should be kept in mind that headache observed especially in HD patients with excessive caffeine consumption may be related to caffeine withdrawal and the presence of caffeine‐withdrawal headache should be questioned among relatives.…”

“…This situation, termed as caffeine-withdrawal headache, is used for patients consuming more than 200 mg of caffeine per day for more than 2 weeks who experience bilateral and/or pulsatile headache within 24 hours after last caffeine intake and disappear within 1 hour after 100 mg caffeine intake. 24 Caffeine-withdrawal headache is described in a HD patient as well. Authors that report headache because of acceleration in caffeine elimination, normal half-life of 2.5-4 hours, during HD mentioned that caffeine-withdrawal headache has a genetic background as well.…”