Caffeic acid-grafted chitosan/sodium alginate/nanoclay-based multifunctional 3D-printed hybrid scaffolds for local drug release therapy after breast cancer surgery

Degradable biomedical elastomers: paving the future of tissue repair and regenerative medicine

“…Alginate, a linear homopolymer composed of β- d -mannuronic acid and α- l -guluronic acid, is easily functionalized and crosslinked, demonstrating potential in DBE design. Teams led by Piozzi 148 and Song 149 focused on designing tissue repair scaffolds around sodium alginate. The grafting designs of dihydrocinnamic acid and caffeic acid effectively promoted scaffold functionalization, while the incorporation of drugs like PySO 3 and curcumin enhanced the material's therapeutic potential for tissue defects.…”

Novel rod‐like carbon nanomaterials as near infrared‐responsive drug delivery system for potential anticancer applications

“…Among them, carbon nanomaterials have attracted extensive attention due to excellent water solubility, high biocompatibility, and low toxicity. In recent years, many carbon nanomaterials such as carbon dots [17], single‐walled carbon nanotubes [18], and graphene oxide [19] have been developed to load anti‐cancer drugs for efficient treatment of tumours. And it is worth mentioning that nanoparticles below 200 nm could cause endocytosis more easily, which made them more suitable in cancer therapy applications [20, 21].…”