“…Metallothioneins (MT) have a crucial role in the intracellular sequestration of copper. In basidiomycetes, such proteins have been functionally characterized in Hebeloma cylindrosporum [ 62 ], Cystoderma carcharias [ 63 ] or Laccaria bicolor [ 64 ], and sequences have been detected in other Basidiomycete species such as Pisolithus arhizus , Paxillus involutus , or Agaricus bisporus [ 62 ]. Surprisingly, these sequences, which were identified in mycorrhizal species, were not found in the R. placenta and P. chrysosporium genomes, suggesting that either such proteins are absent in these wood decay fungi or, alternatively, are too divergent to be detected by our approach.…”