Cadmium "Food Poisoning"

Frant, Samuel; Kleeman, Irving

doi:10.1001/jama.1941.02820280008002

Cited by 28 publications

(3 citation statements)

References 2 publications

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“…Cases of poisoning have been reported involving ingestion of cadmium from food or beverages prepared or stored in cadimum-plated vessels (5,6). In its physiological effects, cadmium is similar to arsenic and mercury (7).…”

Section: Effects Of Cadmiummentioning

confidence: 99%

Contamination of Ground Water by Cadmium

Lieber¹,

Welsch²

1954

Journal AWWA

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Section: Effects Of Cadmiummentioning

confidence: 99%

Contamination of Ground Water by Cadmium

Lieber¹,

Welsch²

1954

Journal AWWA

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“…Cadmium Oral Toxicity: The major sources of oral exposure to cadmium in humans are typically food and incidental ingestion from contaminated hands [16,17]. Very high concentrations of cadmium in food or drinking water can severely irritate the stomach and cause vomiting, diarrhea, and even death [18,19]. Consuming lower levels over a longer period can result in renal concentrations that can damage the kidneys if sufficiently high.…”

Section: Introductionmentioning

confidence: 99%

Minimal Risk Level Derivation for Cadmium: Acute and Intermediate Duration Exposures

Faroon

Keith

Mumtaz

et al. 2017

JECT

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The Agency for Toxic Substances and Disease Registry (ATSDR) lists cadmium as one of its priority hazardous substances. The agency conducted a comprehensive literature review of cadmium and used the information to develop a toxicological profile that identified the full range of health effects associated with exposure to cadmium. It included an assessment that identified screening levels, termed health guidance values or minimal risk levels (MRLs), below which adverse health effects are not expected. In this paper, we describe how MRLs for cadmium are derived. For the acute inhalation MRL, the traditional no observed adverse effect level or lowest observed adverse effect level (NOAEL/LOAEL) approach is used; for the oral intermediate MRL, the benchmark dose (BMD) approach is used. MRLs were developed for the most sensitive route-specific end points, other than mortality and cancer that were sufficiently supported and justified by the data. These included an acute duration (1–14 day exposure) inhalation MRL of 0.03 µg Cd/m3 for alveolar histiocytic infiltration and focal inflammation in alveolar septa and an intermediate duration (15–365 day exposure) oral MRL of 0.5 µg Cd/kg/day for decreased bone mineral density

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“…Absorption of large amounts of cadmium from foods causes nausea, vomiting, stomachache, stomach cramps, and diarrhea [2]. Moreover, long-term intake of cadmium leads to reabsorption disorder in the renal proximal tubules, excretion of low molecular weight proteins, aminoaciduria, dextrosuria, phosphaturia, and even glomerular damage in severe cases [3], which sometimes results in osteomalacia, osteoporosis, fracture, and reduced bone density.…”

Section: Introductionmentioning

confidence: 99%

The association between blood cadmium level, frequency and amount of gejang (marinated crab) intake

Choi

Park

Byun

et al. 2016

Ann of Occup and Environ Med

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BackgroundGejang (marinated crab) is a favorite traditional food and a main source of crab intake among Koreans. The present study aimed to identify the possibility of cadmium inflow to the body through gejang; accordingly, the relationship between gejang intake frequency and amount, and blood cadmium concentrations was investigated.MethodsUsing data from the first Korea National Health and Nutrition Examination Survey in the sixth period in 2013, means and standard errors of blood cadmium concentrations in relation to gejang intake frequency and amount, as well as the monthly intake of gejang, were obtained from 1381 participants for whom data regarding blood cadmium concentration measurements was available.ResultsAfter adjustment for confounding factors, a gejang intake frequency of four or fewer times per week and a monthly intake of 200 cm3 or less had no significant effect on blood cadmium concentrations. However, participants with gejang intake of at least five times per week had a weighted mean cadmium concentration of 2.12 μg/L (p < 0.001), and participants who had a gejang monthly intake of more than 200 cm3 had a weighted mean cadmium concentration of 1.76 μg/L (p < 0.001).ConclusionThese results suggest that to minimize the effect of gejang consumption on blood cadmium level, gejang intake should be limited to four or less times per week and 200 cm3 or less per month. Weekly intake of at least five times and monthly intake of more than 200 cm3 may increase blood cadmium levels.

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Cadmium "Food Poisoning"

Cited by 28 publications

References 2 publications

Contamination of Ground Water by Cadmium

Contamination of Ground Water by Cadmium

Minimal Risk Level Derivation for Cadmium: Acute and Intermediate Duration Exposures

The association between blood cadmium level, frequency and amount of gejang (marinated crab) intake

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