C1 metabolism plays an important role during formaldehyde metabolism and detoxification in petunia under liquid HCHO stress

Zhang, Wei; Tang, Lijuan; Sun, Hao; Han, Shuang; Wang, Xinjia; Zhou, Shengen; Li, Kunzhi; Chen, Limei

doi:10.1016/j.plaphy.2014.08.017

Cited by 16 publications

(6 citation statements)

References 31 publications

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“…Studies on sycamore reveal that serine is the most common source of C1 units and it typically donates one C1 group [16]. A study in Petunia appeared to support the assertion that methionine is the top destination for the C1 group: moderate levels of exogenous labeled formaldehyde mostly ended up in methionine [17]. Formate is another possible source of C1 units (Hourton-Cabassa et al, 1998), although it can be oxidized to yield carbon dioxide and NADH [18], or two molecules of formate can combine to form glyoxylate [19].…”

Section: Methionine Biosynthesismentioning

confidence: 99%

Discovery of Key Molecular Pathways of C1 Metabolism and Formaldehyde Detoxification in Maize through a Systematic Bioinformatics Literature Review

Deonikar¹,

Kothandaram²,

Mohan³

et al. 2015

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Computational systems biology approaches provide insights to understand complex molecular phenomena in living systems. Such understanding demands the need to systematically interrogate and review existing literature to refine and distil key molecular pathways. This paper explores a methodological process to identify key molecular pathways from systematic bioinformatics literature review. This process is used to identify molecular pathways for a ubiquitous molecular process in all plant biological systems: C1 metabolism and formaldehyde detoxification, specific to maize. The C1 metabolism is essential for all organisms to provide one-carbon units for methylation and other types of modifications, as well as for nucleic acid, amino acid, and other biomolecule syntheses. Formaldehyde is a toxic one-carbon molecule which is produced endogenously and found in the environment, and whose detoxification is an important part of C1 metabolism. This systematic review involves a five-part process: 1) framing of the research question; 2) literature collection based on a parallel search strategy; 3) relevant study selection based on search refinement; 4) molecular pathway identification; and 5) integration of key molecular pathway mechanisms to yield a well-defined set molecular systems associated with a particular biochemical function. Findings from this systematic review produced three main molecular systems: a) methionine biosynthesis; b) the methylation cycle; and c) formaldehyde detoxification. Specific insights from the resulting molecular pathways indicate that normal C1 metabolism involves the transfer of a * Corresponding author. P. Deonikar et al.572 carbon group from serine through a folate-mediated pathway to methionine, and eventually the methylation of a biomolecule. In photosynthetic tissues, C1 metabolism often proceeds in reverse towards serine biosynthesis and formate oxidation. C1 metabolism, in maize, appears to be present in the developing embryo and endosperm indicating that these cells are vulnerable to perturbations in formaldehyde detoxification. These insights demonstrate the value of a systematic bioinformatics literature review process from a broad spectrum of domain literature to specific and relevant molecular pathways.

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Section: Methionine Biosynthesismentioning

confidence: 99%

Discovery of Key Molecular Pathways of C1 Metabolism and Formaldehyde Detoxification in Maize through a Systematic Bioinformatics Literature Review

Deonikar¹,

Kothandaram²,

Mohan³

et al. 2015

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“…Even though amino acids are the large group of metabolites in which HCHO-derived carbon is incorporated, little is known about the enzymatic regulation of this process [25,26,28]. Plants contain multiple aminotransferase isoenzymes involved in amino acid synthesis and transformations, localized in various subcellular compartments including peroxisomes, mitochondria, and cytosol, expressed constitutively or in specific conditions [30,65,66].…”

Section: Discussionmentioning

confidence: 99%

“…Amino acids are the large group of metabolites in which HCHO-derived carbon is incorporated. In different plants, HCHO was metabolized and converted to glutamate (Glu), glutamine (Gln), arginine (Arg), asparagine (Asn), serine (Ser), alanine (Ala), methionine (Met), and glycine (Gly) [25,26,28]. Even though there is considerable knowledge regarding the type of amino acids containing carbon derived from HCHO, the knowledge about their synthesis and transformations, as well as the enzymes involved in these pathways in plants treated with HCHO exogenously, is limited.…”

Section: Introductionmentioning

confidence: 99%

New Insight into Short Time Exogenous Formaldehyde Application Mediated Changes in Chlorophytum comosum L. (Spider Plant) Cellular Metabolism

Skłodowska

Świercz-Pietrasiak

Krasoń

et al. 2023

Cells

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Chlorophytum comosum L. plants are known to effectively absorb air pollutants, including formaldehyde (HCHO). Since the metabolic and defense responses of C. comosum to HCHO are poorly understood, in the present study, biochemical changes in C. comosum leaves induced by 48 h exposure to exogenous HCHO, applied as 20 mg m−3, were analyzed. The observed changes showed that HCHO treatment caused no visible harmful effects on C. comosum leaves and seemed to be effectively metabolized by this plant. HCHO application caused no changes in total chlorophyll (Chl) and Chl a content, increased Chl a/b ratio, and decreased Chl b and carotenoid content. HCHO treatment affected sugar metabolism, towards the utilization of sucrose and synthesis or accumulation of glucose, and decreased activities of aspartate and alanine aminotransferases, suggesting that these enzymes do not play any pivotal role in amino acid transformations during HCHO assimilation. The total phenolic content in leaf tissues did not change in comparison to the untreated plants. The obtained results suggest that HCHO affects nitrogen and carbohydrate metabolism, effectively influencing photosynthesis, shortly after plant exposure to this volatile compound. It may be suggested that the observed changes are related to early HCHO stress symptoms or an early step of the adaptation of cells to HCHO treatment. The presented results confirm for the first time the direct influence of short time HCHO exposure on the studied parameters in the C. comosum plant leaf tissues.

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“…Microorganisms present in the plant pot soil and plant root also can remove VOC from indoor air [41]. These plant pollutant removal and degradation strategies have been confirmed using several plant species using radiolabeling [42,43]. Several studies on plants with 14 C labeled aromatic hydrocarbons revealed that aromatic rings of those hydrocarbons were cleaved during their metabolic transformations and utilization of aromatic hydrocarbons under sterile conditions [44].…”

Section: Indoor Pollutant Removal Capability Of Plantsmentioning

confidence: 99%

Plant and Plant Associated Microflora: Potential Bioremediation Option of Indoor Air Pollutants

2021

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Indoor air pollution is a significant problem today because the release of various contaminants into the indoor air has created a major health threat for humans occupying indoors. Volatile Organic Compounds (VOCs) are pollutants released into the environment and persist in the atmosphere due to its low boiling point values. Various types of indoor activities, sources, and exposure to outdoor environments enhance indoor VOCs. This poor indoor air quality leads to adverse negative impacts on the people in the indoor environment. Many physical and chemical methods have been developed to remove or decompose these compounds from indoors. However, those methods are interrupted by many environmental and other factors in the indoor atmosphere, thus limit the applications. Therefore, there is a global need to develop an effective, promising, economical, and environmentally friendly alternatives to the problem. The use of the plant and associated microflora significantly impact reducing the environmental VOC gases, inorganic gases, particulate matter, and other pollutants contained in the air. Placing potted plants in indoor environments not only helps to remove indoor air pollutants but also to boost the mood, productivity, concentration, and creativity of the occupants and reduces stress, fatigue, sore throat, and cold. Plants normally uptake air pollutants through the roots and leaves, then metabolize, sequestrate, and excrete them. Plant-associated microorganisms help to degrade, detoxify, or sequestrate the pollutants, the air remediation, and promote plant growth. Further studies on the plant varieties and microorganisms help develop eco-friendly and environmentally friendly indoor air purifying sources.

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C1 metabolism plays an important role during formaldehyde metabolism and detoxification in petunia under liquid HCHO stress

Cited by 16 publications

References 31 publications

Discovery of Key Molecular Pathways of C1 Metabolism and Formaldehyde Detoxification in Maize through a Systematic Bioinformatics Literature Review

Discovery of Key Molecular Pathways of C1 Metabolism and Formaldehyde Detoxification in Maize through a Systematic Bioinformatics Literature Review

New Insight into Short Time Exogenous Formaldehyde Application Mediated Changes in Chlorophytum comosum L. (Spider Plant) Cellular Metabolism

Plant and Plant Associated Microflora: Potential Bioremediation Option of Indoor Air Pollutants

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