“…Studies carried out by our research group with cattle and sheep demonstrated the benefits of butaphosphane in modulating energy and lipid status. Individuals treated with butaphosphan during periods of intense immunological challenge, as the days around the parturition, demonstrated improved lipid and energy metabolism, resulting in a lower incidence of metabolic disorders and ameliorating productive and reproductive indexes, reflecting a general enhanced health status , Lima, 2014, Tabeleão et al, 2016, Pizoni et al, 2022. However, in this studies, as in others (Rollin et al, 2010, Furll et al, 2010, Temizel et al, 2015, the butaphosphan was used in association with cyanocobalamin (vitamin B12), an enzymatic co-factor of metylmalonyl -CoA mutase, that convert propionate to succinil CoA, an essential step to take part into acid citric cycle, to be used on gluconeogenesis (Kennedy et al, 1990).…”