Burns

Arun, K A; Chandrasekaran, Venkatesh; Gunasekaran, Dhandapany; Nandhini, Veerappan; Narayanan, Veerappan

doi:10.1097/hjh.0000000000000030

Cited by 2 publications

(2 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Measurements taken during the acute phase of burn injury and later right before patient discharge showed that hypertensive patients presented with hypervolemia and perfused at an abnormally high total peripheral resistance compared with their normotensive counterparts (32). Arun et al (10) found a particular incidence of HTN in a child who experienced a 25% TBSA burn and had elevated blood pressure for 96 h until the therapeutic intervention provided stabilization. Zahidi et al (33) discovered through daily blood pressure monitoring of 24 children who developed postburn HTN that the HTN was limited to the acute phase treatment and BP was shown to normalize after complete skin autograft.…”

Section: Discussionmentioning

confidence: 99%

“…Although burn is considered to be unrelated to causes of essential HTN, the incidence of new-onset HTN after burn injury is 19.8% (8,9). Potential pathophysiology includes an overactive fluid correction by the renin-angiotensin-aldosterone system during active vasoconstriction response to burn injury (10). A hypermetabolic stress response is also commonly noted in patients who sustain burn injury encompassing more than 20% of the total body surface area (TBSA) (11).…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

The Risks of First Onset Primary Hypertension Diagnosis in Thermal-Injured Patients

Efejuku,

Wolf,

Song

et al. 2024

Shock

View full text Add to dashboard Cite

INTRODUCTION Hypertension (HTN) is a prevalent condition in the United States and leads to an increased risk of developing various comorbidities. However, the impact of new-onset hypertension following severe burns on patient outcomes is not known. We posit that hypertension onset after severe burn is associated with increased risk of developing comorbidities and mortality. METHODS Using the TriNetX database, burned patients diagnosed with essential hypertension after injury were compared to those who did not develop hypertension; neither had prior hypertension. Each cohort was grouped by sex, percent total body surface area (TBSA) burned, and age, then propensity-matched for sex, race, ethnicity, and lab values. Outcomes assessed were acute kidney injury (AKI), hyperglycemia, heart failure, myocardial infarction (MI), and death. RESULTS Those diagnosed with hypertension following severe burn were 4.9 times more likely to develop AKI, 3.6 times for hyperglycemia, 5.3 times for heart failure, 4.7 times for acute MI, and 1.5 times for mortality. Sex analysis shows that men were at greater risk for AKI (1.5 times), heart failure (1.1 times), and death (1.4 times). Women were 1.3 times more likely to develop hyperglycemia. Percent TBSA burned grouping showed increased risk for all outcomes with increasing severity. Age grouping indicated an elevated risk of developing AKI, heart failure, acute MI, and death. CONCLUSION New onset hypertension diagnosis in severely burned patients is associated with acute kidney injury, heart failure, acute MI, and death. Overall, males, older patients, and those with a higher % TBSA burned are at a higher risk of developing these comorbidities.

show abstract

Section: Discussionmentioning

confidence: 99%