Burning Mouth Syndrome Induced by Angiotensin-Converting Enzyme Inhibitors

Abstract

Burning mouth syndrome (BMS) is characterized as the sensation of burning in the tongue or any other area of the oral mucosa without a medical or dental cause. BMS's pathophysiology is poorly understood and may be caused by its association with various factors, particularly with antihypertensive or psychotropic medicines. Although BMS is a relatively common intraoral disorder in the dental field, emergency physicians rarely recognize it. We report a 53-year-old Japanese woman who presented to our ED with a three-week history of a strange taste and burning tongue. The patient had poor control of hypertension, captopril, an angiotensin-converting enzyme (ACE) inhibitor, was added three weeks before presentation. We discontinued her ACE inhibitor and changed her medication to a beta-blocker. After two weeks, her symptoms improved. Emergency physicians must be aware that ACE inhibitors play some roles in the pathogenesis of BMS. The correct diagnosis of the condition depends on recognizing the disease and improving the quality of life.

The Surprising Connections between Oral Health & Well Being! Routine Oral Checks- A missed Opportunity for Dental, Oral & Overall, Health!

“…A few case reports of scalded mouth syndrome have been reported with ACE Inhibitors, our case number 4 is one of them. A scalded sensation of the oral mucosa during the treatment with captopril or enalapril was initially reported [8].…”

Non-Communicable Diseases and Associated Risk Factors in Burning Mouth Syndrome Patients

“…(2) positivity at an oral fungal test and remission of the symptoms after treatment; and (3) dental, occlusal, and temporomandibular joint disorders inducing pain mimicking BMS symptomatology. As some authors have reported an association between BMS and the use of angiotensin-converting enzyme inhibitors (ACE inhibitors) [25,26], we referred the patients using ACE inhibitors to the cardiologists to replace this therapy. In 3 patients, the BMS symptoms remitted after 1 month of the replacement medication, and the patients were excluded from our study.…”

Degančios Burnos Sindromas

“…Arminas Zizas 1 , Austėja Judickaitė 1 , Rūta Pribuišienė 2 1 Lietuvos sveikatos mokslų universiteto Medicinos akademijos Medicinos fakultetas, 2 Lietuvos sveikatos mokslų universitetas, Ausų, nosies ir gerklės ligų klinika 214 nergine reguliacija [7]. Prie etiologinių priskiriamas cirkadinio ritmo sutrikimas, galintis sukelti arba pabloginti esamą būklę [9]. Dėl mažo atliktų tyrimų kiekio, sudėtingos diagnostikos, etiologija ir patogenezė lieka neaiški, manoma, kad priežastis yra daugiaveiksnė [9].…”

“…Prie etiologinių priskiriamas cirkadinio ritmo sutrikimas, galintis sukelti arba pabloginti esamą būklę [9]. Dėl mažo atliktų tyrimų kiekio, sudėtingos diagnostikos, etiologija ir patogenezė lieka neaiški, manoma, kad priežastis yra daugiaveiksnė [9]. Klinika.…”