Burkholderia vietnamiensis Causing a Non-lactational Breast Abscess in a Non-cystic Fibrosis Patient in Tamil Nadu, India

Rohit, Anusha; Rani, Mridula; Anand, N.; Chellappa, Cynthia; Karunasagar, Indrani; Deekshit, Vijaya Kumar

doi:10.4103/ijmm.ijmm_20_329

Cited by 6 publications

(12 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Our patients also had no immunosuppressant factor. We could nd only one documented report of BA due to Bcc (Burkholderia vietnamiensis) in the literature [10]. Rarely, Burkholderia pseudomalai has been isolated in BA or cutaneous melioidosis of skin overlying breast.…”

Section: Discussionmentioning

confidence: 98%

“…However, up to 40% of BAs are polymicrobial, with aerobic (Staphylococcus, Streptococcus, Enterobacteriaceae, Corynebacterium, Escherichia coli, and Pseudomonas) and anaerobic infection (Peptostreptococcus, Propionibacterium, Bacteroides, Lactobacillus, Eubacterium, Clostridium, Fusobacterium, and Veillonella) [2]. Rarely uncommon organisms like Salmonella paratyphi A, Burkholderia pseudomallei, Burkholderia vietnamiensis, Trueperella bernardiae, Actinotignum sanguinis may cause BA [7][8][9][10][11].…”

Section: Discussionmentioning

confidence: 99%

“…Burkholderia contaminans, a nonfermenting Gram-negative aerobic bacillus, previously known as taxon K or group K, was recognized as novel species MLST-1 in 2009 using multilocus sequence typing [15]. Among Bcc, most human cases are associated with Burkholderia cenocepacia and Burkholderia multivorans, while Burkholderia contaminans is less frequently encountered in human infections [10,16]. Burkholderia contaminans is an opportunistic pathogen with low virulence but extensive virulence factors.…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Non-lactational Breast Abscess due to Burkholderia Contaminans – Case Report of a Rare Organism with Rare Presentation

Pal

Dutta

Jain

et al. 2022

Preprint

View full text Add to dashboard Cite

Introduction: A breast abscess (BA) is a localized collection of purulent materials within breast tissues. BA are most frequently present during the lactational period, but they can rarely manifest in the non-lactational period. Staphylococcus aureus is the most common causative organism, mostly methicillin-resistant S. aureus, followed by coagulase-negative Staphylococci. Burkholderia contaminans is an uncommon opportunistic infection commonly associated with cystic fibrosis. BA due to a Burkholderia contaminans infection has never been reported previously. Case Presentation: We are reporting a 25-year-old immunocompetent woman with a non-lactational left BA caused by Burkholderia contaminans. She complaints of gradually progressive lump in her left breast for one year. Local examination revealed a tender swelling with induration and soft central region in the lower inner and outer quadrant suggestive of BA with palpable left axillary lymph node. She was successfully treated with ultrasound-guided needle aspiration followed by a course of culture-based antibiotics. Conclusions: Burkholderia contaminans is one of the 24 species in the Burkholderia cepacia complex (Bcc). Burkholderia contaminans is an extremely rare opportunistic pathogen with low virulence but extensive virulence factors. Bcc infection can vary from an asymptomatic carrier, chronic infection ranging from pulmonary involvement to invasive Bcc, and life-threatening presentation like cepacia syndrome, especially in CF and chronic granulomatous disease patients. In our patient symptoms of BA was chronic with recent aggravation. BA should be managed by incision and drainage or image guided needle aspiration, undercover of enteral or parenteral antibiotics depending upon severity of the disease.

show abstract

Section: Discussionmentioning

confidence: 98%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Non-lactational Breast Abscess due to Burkholderia Contaminans – Case Report of a Rare Organism with Rare Presentation

Pal

Dutta

Jain

et al. 2022

Preprint

View full text Add to dashboard Cite

show abstract

“…We further found that the drug-resistant genes of this strain were mphL, satA_Ba, BcII, and bla1 via the second-generation sequencing of the whole genome. 3 The cerebrospinal fluid examination (CSF) was performed to rule out intracranial infection, and no positive results were seen in the CSF, including CSF routine, culture, Cryptococcus neoformans, Mycobacterium tuberculosis and NGS. She was…”

Section: Case Reportmentioning

confidence: 99%

“…1 Several cases report that B. cepacia could induce extrapulmonary-tissue abscesses, such as brain, bilateral psoas, chest intra-abdominal, and deep neck. [2][3][4][5][6][7][8] However, soft tissue infections with fractures caused by B. cepacia are extremely rare with no instances reported. We report a middle-aged female with a medical history of 3-year brain dead who developed a subcutaneous abscess with a bone fracture in her right occipital region.…”

Section: Introductionmentioning

confidence: 99%

Burkholderia cepacia Induced Occipital Subcutaneous Abscess and Fracture in a Brain-Dead Woman

Wu¹,

Liu²,

Chen³

et al. 2023

IDR

View full text Add to dashboard Cite

Burkholderia cepacia is an aerobic opportunistic Gram-negative pathogen that mainly infects immunodeficiency patients. However, soft tissue infections with fractures due to Burkholderia cepacia are rare with no cases reported. Here, we report a rare case of 3 years of brain death in a 43-year-old woman with Burkholderia cepacia resulting in an occipital subcutaneous abscess and fracture. Through the second-generation sequencing of the whole genome of this strain, it was found that there were no high virulence genes and virulence factors. The patient received targeted antibiotic therapy and showed improvement in clinical symptoms and radiological signs. Bone destruction because of Burkholderia cepacia is easily overlooked due to the lack of characteristic symptoms and limited clinical examination. This case reminds us that Burkholderia cepacia without major virulence factors could damage the bone in immune-compromised patients.

show abstract

Comparative analysis of different methods used for molecular characterization of Burkholderia cepacia complex isolated from noncystic fibrosis conditions

Modapathi

Rohit

Aditya

et al. 2022

Indian Journal of Medical Microbiology

View full text Add to dashboard Cite

Burkholderia vietnamiensis Causing a Non-lactational Breast Abscess in a Non-cystic Fibrosis Patient in Tamil Nadu, India

Cited by 6 publications

References 19 publications

Non-lactational Breast Abscess due to Burkholderia Contaminans – Case Report of a Rare Organism with Rare Presentation

Non-lactational Breast Abscess due to Burkholderia Contaminans – Case Report of a Rare Organism with Rare Presentation

Burkholderia cepacia Induced Occipital Subcutaneous Abscess and Fracture in a Brain-Dead Woman

Comparative analysis of different methods used for molecular characterization of Burkholderia cepacia complex isolated from noncystic fibrosis conditions

Contact Info

Product

Resources

About